摘要:

ABSTRACTOne hundred and twenty‐seven cases of histiocytosis in Bernese mountain dogs (BMD) were evaluated to determine if the tumour is inherited. Family data ruled out autosomal recessive, autosomal dominant and sex‐linked modes of inheritance. The trait was determined to be inherited with a polygenic mode of inheritance. The salient points permitting this conclusion are: pedigrees developed from independently selected propositi link up allowing the tracing of all cases through several generations; multiple cases occur in the same litter; multiple cases have been produced by given dams and sires; there is a higher frequency of the disease among offspring of affected parents when compared to offspring of normal parents that produced histiocytosis and all offspring in the general population of BMDs; the fact that histiocytosis is common in BMDs and rare in eight other breeds and accounts for 25·4 per cent of the 500 tumours studied in this breed. The heritability of this trait was calculated to be 0

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02838.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02839.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTA randomised double‐blind parallel study compared the clinical and antimicrobial efficacies of a miconazole‐chlorhexidine shampoo with a selenium sulphide shampoo for the treatment of seborrhoeic dermatitis associated withMalassezia pachydermatisin 33 basset hounds. All 16 miconazole‐chlorhexidine treated hounds and 11 of 17 selenium sulphide treated hounds improved when shampooed at three‐day intervals for three weeks. The miconazole‐chlorhexidine treated hounds showed significantly greater reductions in pruritus (P<0·01), erythema (P<0·001), exudation (P<0·01) and overall severity (P<0·001), and in counts ofM pachydermatis(P<0·001), total bacteria (P<0·001) and coagulase‐positive staphylococci (P<0·001), when compared to the selenium sulphide treated group. Improvements in scaling and coat condition did not vary significantly between the two groups. These results indicate that seborrhoeic dermatitis in basset hounds is often assoc

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02840.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02842.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTPercutaneous sampling of one or more abdominal organs was performed under ultrasound guidance in 89 dogs and 16 cats. Tissue core samples were considered to be of diagnostic quality in 92 per cent of hepatic and 100 per cent of renal biopsies. Core biopsies were collected from the prostate in only three cases but each was adjudged of diagnostic quality. The technique allowed a definitive diagnosis or normal tissue to be confirmed in 65 per cent of animals undergoing hepatic biopsy, 83 per cent undergoing renal biopsy and 82 per cent undergoing prostatic biopsy or aspiration. Few complications occurred which could be ascribed with certainty to the procedure. One dog with extensive hepatic necrosis died one week after the biopsy, but necropsy examination was denied. One severely debilitated cat did not recover from general anaesthesia. One dog underwent aspiration of a sterile intraprostatic cyst, and developed prostatic abscessation one week later; prostatic carcinoma was subsequently found. Careful selection and preparation of patients for biopsy are essential. With this caveat, ultrasound‐guided sampling of abdominal organs is a useful technique allowing a definitive diagnosis in a high proportion of cases. The technique is minimally invasive and the complication rate lo

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02843.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02845.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02847.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTDeficiencies of the vitamin K‐dependent coagulation factors were identified in a Devon rex cat which had bled after castration. Haemorrhage was controlled by plasma transfusion. Clotting times were normalised by oral administration of vitamin K. This report confirms the existence of this bleeding disorder in a Devon rex cat in the United Kingdo

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02848.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02849.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY

摘要:

ABSTRACTThe historical, clinical and histopathological features of three dogs with eosinophilic folliculitis and furunculosis are described. The disease was characterised by the rapid development of pruritic, papular, pustular and ulcerative lesions on the dorsum of the muzzle. Skin lesions were confined to the face in two cases. The third dog had more generalised pustular lesions. Skin biopsy specimens showed marked eosinophil infiltration particularly centred on pilosebaceous units. Dermal collagen necrosis was evident in two cases. Similar facial lesions have previously been described as ‘nasal pyoderma’. The three dogs failed to respond to initial antibacterial therapy but showed a rapid clinical response when prednisolone was given orally at doses ranging from 1 to 2‐2 mg/kg, in addition to the antibacterial therapy, suggesting that glucocorticoids are indicated for the treatment of eosinophilic folliculitis and furunculosis. The aetiology of the disease was not deter

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1995.tb02850.x

出版商:Blackwell Publishing Ltd    

年代:1995

数据来源: WILEY