摘要:

ABSTRACTFifty‐one dogs bearing a variety of naturally occurring tumours were treated with combined radiation and hyperthermia. The treatment regime consisted of four, weekly fractions of radiation to a total dose of 3600–4000 cGys and one or two treatments with local microwave hyperthermia, heating the tumour to 44°C for 30 minutes on each occasion.Twenty‐six (51 per cent) of the tumours showed a complete response to this treatment and a further eighteen (35 per cent) tumours underwent significant regression giving a total response rate of 86 per cent. Sixteen tumours later recurred at intervals of 11–50 weeks post treatment. The majority of tumours were in the oral cavity (35 cases) and in this group the survival rate compares favourably with figures for surgical treatment and radiotherapy alone.These findings support published results from other centres, indicating that hyperthermia combined with radiotherapy is a potentially useful technique for the management of certain canine malignant

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01440.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTFour cases of Labrador Retriever myopathy are described. These examples have been chosen to illustrate the variation in clinical signs which may be seen in this condition, and include the first example of a confirmed case of Labrador Retriever myopathy in which mega‐oesophagus has been reported as a complicating feature. The implications of the clinical variations in diagnosis, management and control of the condition are discusse

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01441.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTPrimary hyperplastic gastropathy is an uncommon human disease characterized by giant gastric mucosal folds and is associated with a spectrum of histopathological changes. Diagnosis is usually made on radiological and gastroscopic findings followed by full‐thickness biopsy of the stomach wall. The aetiology is unknown and symptomatic treatment is usually disappointing. A similar condition has been described in a small number of dogs.A case of hyperplastic gastropathy is reported in a cat and compared with the findings in man and dogs. The cat presented with chronic vomiting and weight loss. Radiological and gastroscopic examinations revealed enlarged gastric rugae. Medical and surgical treatment was unsuccessful and the cat was destroyed. The pathological findings were similar to those described in ma

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01442.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTThe clinical, radiological and histopathological features of 30 thyroid tumours in the dog are described. Ten tumours were considered suitable for surgical removal and in a follow‐up period of between 14 and 36 months five dogs were still aliv

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01443.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTA five‐year‐old female English Springer Spaniel was evaluated for chronic episodic anaemia, pigmenturia and icterus. There was increased erythrocyte pyruvate kinase activity, increased in vitro erythrocyte alkaline fragility, decreased erythrocyte 2,3‐diphosphoglycerate activity and severely decreased erythrocyte phosphofructokinase activity. The clinical features and haematological values were identical with erythrocyte phosphofructokinase deficiency and resulting nonspherocytic haemolytic anaemia recently described in this

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01444.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTA case of Harada's disease (uveodermatological syndrome) in a 14‐month old female Japanese Akita is reported, the first record of this syndrome in the United Kingdom. This case was characterized by uveitis, dermatitis and some CNS involvement. The neurological component in this syndrome has not previously been reported in the dog. The Japanese Akita is a breed only recently introduced into the United Kingdom and in view of the small gene pool available the recognition of a syndrome with an apparently hereditary basis is of particular importanc

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01445.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTThe resistance of canine parvovirus (CPV) to inactivation by chemical and thermal means was investigated. CPV with and without extraneous protein was tested against 15 commonly used disinfectants at room temperature. The titres of CPV remaining after 5 minutes disinfection time were greater than or equal to those remaining after 30 minutes regardless of the presence or absence of protein. Disinfection of CPV was accomplished more quickly and at lower concentrations of disinfectants when extraneous protein was absent. Halogen compounds, aldehydes and sodium hydroxide were the most acceptable CPV disinfectants. The presence of protein interfered with the two most frequently recommended CPV disinfectants—sodium hypo‐chlorite and formaldehyde. The resistance of CPV to inactivation by heat depended on the temperature and the duration of heating. Boiling (100°C) rapidly inactivated CPV. The virus was more resistant to lower temperatures. Detectable infectivity remained after 7 hours at 80°C and 72 hours at 56°C. At both 37°C and room temperature there was no significant change in infectivity titres over 7

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01446.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTThree important criteria which the clinician should consider when selecting an antibiotic are its antibacterial spectrum, pharmacokinetic properties, and potential toxicity. Pharmacokinetics is a study of how the body handles drugs: that is, their absorption, distribution in the tissues (an antibiotic must reach the site of infection in effective concentration), metabolism and excretion.This article reviews these criteria with respect to chloramphenicol in dogs and cats.

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01447.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

ABSTRACTThe indications and contraindications for the use of chloramphenicol are reviewed and some suggestions made regarding the use of this drug in small animal practice.

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01448.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

ISSN:0022-4510    

DOI:10.1111/j.1748-5827.1987.tb01449.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY