1. |
The Sézary Syndrome |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 397-403
W. Goor,
C. Maier,
W. Fierz,
F. Ott,
G. Pedio,
J.R. Rüttner,
W. Schmid,
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摘要:
Symptoms of the Sézary syndrome are described in a case history. Sézary’s syndrome is a lymphoproliferative process of the skin, which eventually develops into an erythrodermia. Strange lymphocytes with a cerebriform chromatin structure, often with T-cell characteristics, circulate in the blood stream. In few instances they are also found in lymphnodes and bone marrow. This primarily benign disease can become malignant, possibly due to an overaggressive cytostatic therapy. Besides the hitherto unknown endogenous causes, exogenous factors cannot be exclu
ISSN:1018-8665
DOI:10.1159/000250789
出版商:S. Karger AG
年代:1979
数据来源: Karger
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2. |
Ichthyosis linearis circumflexa Comèl and Netherton’s Syndrome; an Ultrastructural Study |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 404-412
Alberto M. Zina,
Silvana Bundino,
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摘要:
An electron microscopic study of 3 cases of ichthyosis linearis circumflexa Comèl (ILC) reveals the presence of round bodies in the prickle cells: a characteristic feature of ILC. The horny and the granular layers are absent and are replaced by parakeratotic cells with condensed cytoplasm, which an amorphous material dissociates. The early formation of a vesiculopustule is detected. The importance of the dermal inflammation is considered and it is stated that ILC is not a purely epidermal disorder of keratinization
ISSN:1018-8665
DOI:10.1159/000250790
出版商:S. Karger AG
年代:1979
数据来源: Karger
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3. |
Intranuclear Particles in Keratoacanthoma: Possible Association with Malignant Degeneration |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 413-416
W.J.B.M. van de Staak,
A.M.G. Bergers,
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摘要:
Electron microscopic investigation of 12 patients with keratoacanthoma is reported. Intranuclear virus-like particles, as described by Zelickson and Lynch, were seen in 3 cases; 2 of these subsequently underwent malignant degeneration. These findings suggest that it is particularly important to exclude the possibility of malignant change in those tumours when intranuclear particles are found.
ISSN:1018-8665
DOI:10.1159/000250791
出版商:S. Karger AG
年代:1979
数据来源: Karger
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4. |
Immune Complex Disease Associated with Peroben® Intake |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 417-426
D. van Neste,
G.E. Piérard,
J.F. Hermanns,
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摘要:
The clinical history and biological investigations of a patient presenting an immune complex disease induced by Peroben® are reported. Biological signs were those of a drug-induced lupus syndrome. A provocation test allowed disclosure of its pathomechanism, since during Peroben intake a high Clq binding activity occurred and later regressed, while deposits of IgM and C3 were evidenced in the vessel walls. Complete or partial thrombosis succeeded accompanying a leukocytoclastic vasculitis
ISSN:1018-8665
DOI:10.1159/000250792
出版商:S. Karger AG
年代:1979
数据来源: Karger
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5. |
Direct Immunofluorescence Studies in Granuloma annulare, Necrobiosis lipoidica and Granulomatosis disciformis Miescher |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 427-432
C. Nieboer,
G.L. Kalsbeek,
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摘要:
Direct immunofluorescence studies in granuloma annulare, necrobiosis lipoidica and granulomatosis disciformis Miescher are reported. In all 29 cases fibrillar deposits of fibrin in the necrobiotic areas have been found. Complement, mainly C3, was present in the region of the dermo-epidermal junction in 83% of the cases. Although the walls of the vessels in the superficial layers of the dermis showed a positive staining with antifibrinogen and complement, those around the necrobiotic areas were negative in most of the cases. The possible significance of these findings for the pathogenesis has been discussed.
ISSN:1018-8665
DOI:10.1159/000250793
出版商:S. Karger AG
年代:1979
数据来源: Karger
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6. |
Diffuse Biphasic Cutaneous Amyloidosis |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 433-437
T.R. Bedi,
B.N. Datta,
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摘要:
2 patients with primary localized cutaneous amyloidosis were seen to have widespread macular and lichenoid types of lesions. Diffuse areas of pigmentation appeared to transform gradually over years into lichen amyloidosus as a result of chronic irritation of the skin from scratching. There was no evidence of systemic amyloidosis.
ISSN:1018-8665
DOI:10.1159/000250794
出版商:S. Karger AG
年代:1979
数据来源: Karger
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7. |
Morphaea-like Cutaneous Changes in a Patient with Systemic Scleroderma |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 438-442
Kouichi Ikai,
Hachiro Tagami,
Sadao Imamura,
Minoru Hayakawa,
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摘要:
A case of systemic scleroderma with peculiar morphaea-like lesions is reported. The patient at first started with typical acrosclerosis, some parts of which later became softened and apparently resumed the appearance of normal skin, so that morphaea-like cutaneous plaques which remained hard, were soft. These changes were surrounded by erythema resembling the ‘lilac ring’ as noted in characteristic active lesions of morph
ISSN:1018-8665
DOI:10.1159/000250795
出版商:S. Karger AG
年代:1979
数据来源: Karger
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8. |
Low-Dose Chlorambucil in the Treatment of Generalized Granuloma annulare |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 443-450
Steven Kossard,
R.K. Winkelmann,
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摘要:
5 of 6 adults with generalized granuloma annulare responded favorably to therapy with low-dose chlorambucil. 5 of the patients had lesions that were recurrent and long-standing and that resisted conventional modalities of therapy. Low-dose chlorambucil may be effective in a short-term therapy program but should be used only in patients with persistent, widespread, or unusual forms of generalized granuloma annulare. The program requires close patient and hematologic supervision.
ISSN:1018-8665
DOI:10.1159/000250796
出版商:S. Karger AG
年代:1979
数据来源: Karger
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9. |
Skin Petechiae and Ecchymoses (Vasculitis) Due to Anticoagulant Therapy |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 451-461
M. Stavorovsky,
D. Lichtenstein,
F. Nissim,
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摘要:
The appearance of petechiae and ecchymoses following anticoagulant and fibrinolytic therapy is an unusual and rare complication. The mechanism of the vasculitis is obscure but may be related to a chemical vasotoxic reaction. During anticoagulant and fibrinolytic therapy, 6 patients developed petechiae and ecchymoses which was accompanied by pain and fever. There were no disturbances of blood clotting factors. In spite of the varied action of the different anticoagulants and fibrinolytic drugs, the clinical course and the histological examination demonstrated a similar identical vasculitis.
ISSN:1018-8665
DOI:10.1159/000250797
出版商:S. Karger AG
年代:1979
数据来源: Karger
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10. |
PUVA Treatment in Mycosis Fungoides |
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Dermatology,
Volume 158,
Issue 6,
1979,
Page 462-467
K.-M. Niemi,
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摘要:
2 patients with mycosis fungoides at the plaque stage were treated with oral methoxalen and UVA irradiation. 3 months later both developed the skin tumours with highly malignant histological picture. In 1 patient at the tumour stage the skin tumours were spreading during the PUVA treatment. 3 patients at the first or eczematoid stage cleared completely or partially by PUVA treatment.
ISSN:1018-8665
DOI:10.1159/000250798
出版商:S. Karger AG
年代:1979
数据来源: Karger
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