摘要:

The HL-A typing of 90 psoriasic patients did not show any real correlation between histocompatibility antigens and psoriasic arthropathy. The study of families of 60 psoriasic patients has shown that the disease was twice as frequent among the close relatives of patients with W17 antigen. However, the HL-A typing of 4 families where several members were found to have the disease has shown that psoriasis may be transmitted independently of W17.

ISSN:1018-8665    

DOI:10.1159/000251613

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Report of 2 patients with brownish, ill-defined macules on their fingers, in one case also on elbows and knees. Light microscopy revealed identical changes in both cases: scattered, swollen, vacuolated, clear keratinocytes in the suprabasal epidermis and horny layer. Electron microscopy showed alterations which were interpreted as hydropic degeneration of keratinocytes.

ISSN:1018-8665    

DOI:10.1159/000251614

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Electron microscopic investigations on biopsies, taken from one patient with malignant melanoma and two with keratoma palmoplantare, have revealed that many keratinocytes contain numerous intracytoplasmic desmosomes, especially in melanoma. Most of them are interconnected by membrane structures for building large complexes. These intracytoplasmic desmosomes, which are 250–500 nm long and about 80 nm wide, partly show granular contact layer. The attachment plaques are surrounded by either filamentous or granular structures, which possibly induce the formation of the desmosomes. We suppose that these desmosomes partly come into the cytoplasm by invaginations of certain areas of the cell membrane, however, another part may be formed intracytoplasmically after invaginating of such sites of the cell membran

ISSN:1018-8665    

DOI:10.1159/000251615

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Dequalinium chloride is a quaternary ammonium compound used for the treatment of infected skin and mucosal lesions. Its influence on the healing of incisional wounds in rat skin has been studied by a tensiometric technique. The breaking load was significantly lower in wounds that had been exposed to an aqueous solution of dequalinium chloride than those exposed to distilled water. The concentrations of dequalinium chloride were well below those used in clinical practice. The results obtained from incisional wounds are probably valid also for open wounds. The results are correlated with the microcirculatory disturbances demonstrated in previous studies. This suggests that the use of dequalinium chloride in treating human wounds should be re-evaluated.

ISSN:1018-8665    

DOI:10.1159/000251616

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

The fact that many modifications of the technique originally elaborated by Mckenzie and Stoughton for skin vasoconstriction assay have been introduced considerably complicates the task of making a comparative appraisal of the methods used and the results obtained. Despite the large sources of variance, the rank orders of most topical corticoids obtained in tests carried out according to widely varying techniques by many different investigators are relatively consistent. An effort should be made to achieve a higher degree of concordance between different investigators – which applies also to the rank intervals and absolute potency values – by devising and adhering to a standardized proced

ISSN:1018-8665    

DOI:10.1159/000251617

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Our own experience with the treatment of smallpox scars on the face is described. Note is taken of the fact that results are esthetically superior when treatment has been applied later after illness. The pathologic finding of epidermal adnexal organs at certain stages of the cicatrization process, which is incompatible with regenerative capabilities of the skin-forming organ, was unexpected.

ISSN:1018-8665    

DOI:10.1159/000251618

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

A case of peculiar eruption in a 43-year-old man is reported. The eruption was papular, polymorphic, hyperkeratotic, and lichenoid appearing on 4dry skin with patches, linear striation and Sverrucous hyperkeratosis. The histological picture showed a lichenoid lymphohistiocytic infiltrate with hyperkeratosis, hypergranulosis and parakeratosis ‘in cutem penetrans’. The general examination and laboratory findings were normal. Only seven cases have been previously reported. The first one was described by Kaposi, and in four of them there were also mucosal lesions. The differential diagnosis is made with the hypertrophic lichen planus and with the lichen of toxic ori

ISSN:1018-8665    

DOI:10.1159/000251619

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

The inflammatory linear verrucose epidermal nevus is a recently individualized special type of linear nevus. The particular features of this nevus are represented clinically by the pruritus and the erythematous, scaly, at times psoriasiform and frequently lichenifled aspect of the papulokeratotic lesions. Histologically, this disease is characterized by a psoriasiform picture or that of chronic eczema with, in some instances, the alternation of areas of agranulosis and hypergranulosis accompanied, respectively, by overlying parakeratosis and orthokeratosis. These areas are very sharply separated. The authors report a case and discuss the clinical and histologic criteria which justify the autonomy of this nevus, as well as the differential diagnosis, the etiopathogenesis, its relation to the ‘epidermal nevus syndrome’ of Solomon et al. and its treatm

ISSN:1018-8665    

DOI:10.1159/000251620

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000251621

出版商:S. Karger AG    

年代:1974

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000251622

出版商:S. Karger AG    

年代:1974

数据来源: Karger