摘要:

A study of 96 patients with an original diagnosis of mycosis fungoides revealed that 84 did not have circulating Sézary cells. Of the 12 patients with Sézary cells, only 3 had more than 15%. The 12 patients had benign and malignant skin diseases. The Sézary cell does not seem to have any importance in the pathogenesis of mycosis fungoid

ISSN:1018-8665    

DOI:10.1159/000250477

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Carcinoma erysipelatodes (inflammatory metastatic carcinoma) is a rare metastatic carcinoma in the skin. It is usually associated with breast carcinoma, and the prognosis is short-termed. It closely resembles an acute infection, such as erysipelas or cellulitis. 2 patients with this syndrome are presented. One of them had carcinoma of portio uteri. The clinical appearance and the histological pathognomony are described, and a review of the literature is given.

ISSN:1018-8665    

DOI:10.1159/000250478

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Microscopic tissue sections stained for bacteria were studied from autopsy material from a fatal case of scleroderma (progressive systemic sclerosis). Extra- and intracellular, variable-sized, pleomorphic but predominantly coccoid bacteria were observed in some organs such as in heart, lungs, adrenals, kidneys, pancreas, skin, and in the connective tissue. An attempt is made to correlate the ante-mortem skin culture material with the post-mortem histopathologic finding of bacteria. It is hypothesized that these microbes observed in tissue might represent in vivo, cell wall deficient L forms, which may be implicated in the pathogenesis of scleroderma.

ISSN:1018-8665    

DOI:10.1159/000250479

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

77 Vitiligo patients were investigated for their HLA phenotype. Analysis of this material according to age of onset and ethnic origin revealed some significant characteristics. Young Jewish Moroccan patients showed a high frequency of B13 when compared to matching controls. Young patients of Yemenite origin had a strikingly high frequency of BW35. Jewish Yemenites showed a lack of B13 both in patients and in controls. It is suggested that studies be undertaken to clarify this problem further.

ISSN:1018-8665    

DOI:10.1159/000250480

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

2 children with undue susceptibility to skin infections and isolated defective neutrophil bacterial killing are described. Since the NBT-reducing capabilities of granulocytes were normal, a mild form of chronic granulomatous disease was excluded. Ascorbic acid was effective in delaying and eventually suppressing infectious episodes.

ISSN:1018-8665    

DOI:10.1159/000250481

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

A case of dyskeratosis congenita with depressed responsiveness to policlonal mitogens (PHA, Con-A, PKM) and negative skin tests (PPD, SK-SD, Candidin, Trichophytin) is reported. Chromatid breaks and reduction of the capacity of DNA repair were also present. The findings are discussed in relationship to the prognosis of dyskeratosis congenita.

ISSN:1018-8665    

DOI:10.1159/000250482

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

In 20 patients with severe herpes simplex, the combined use of levamisole 150 mg/day for 3 days every 2 weeks, plus indomethacin 25 mg daily for a maximum period of 6 months, gave some 75% favourable results.

ISSN:1018-8665    

DOI:10.1159/000250483

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Levamisole has been used to treat a patient with disseminated neonatal herpes simplex infection. The skin lesions and the convulsions disappeared completely 20 days after therapy. A trial to reduce the dose of levamisole resulted in a new episode of seizures and skin lesions. A similar relapse was observed at the age of 7 months, which resulted in control of symptoms by increasing the dose of levamisole. The patient has received levamisole for 20 months. She is now 29 months old and is doing well without levamisole, except for a slight motor deficit. If further investigations confirm the present findings, levamisole may well become a useful agent in the treatment of disseminated herpes simplex infection.

ISSN:1018-8665    

DOI:10.1159/000250484

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Extensive necrosis of the skin, muscle and bone was produced after prolonged cooling in a case of myeloma with cryoglobulinemia. Skin grafting was beneficial.

ISSN:1018-8665    

DOI:10.1159/000250485

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

The in vitro addition of mite or human unparasited scale extracts to the serum of 8 patients with scabies and 5 healthy controls did not significantly modify the fixation of 125I-C1q as compared to control tubes (serum with physiological saline). These results suggest that antigens or substances derived from the scabies mite are not involved in the immune complexes present in the serum of the parasited patients.

ISSN:1018-8665    

DOI:10.1159/000250486

出版商:S. Karger AG    

年代:1980

数据来源: Karger