ISSN:1018-8665    

DOI:10.1159/000249913

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Electron microscopy revealed accumulation of fibrogranular materials associated with laminated basal lamina around the smooth muscle cells of tunica dartos (most strikingly) and of blood vessels, vascular endothelial cells, pericytes, myofibroblasts (not usual fibroblasts) as well as Schwann cells and perineuria. Around the presumably regressive and slightly shrunken sweat duct, a network of basal lamina containing fibrogranular materials was found in a configuration indicating that it would have surrounded the remnants of cells (involuted cells) of the sweat duct, probably consisting of old, undegradated, residual basal lamina. Consequently, it was suggested that hyalinosis cutis et mucosae might be caused by accumulation and invasion of basal lamina glycoprotein involving the type IV (plusV?) collagen into normal collagen fibers (bundles) due to defective degradation.

ISSN:1018-8665    

DOI:10.1159/000249914

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A case of tricho-rhino-phalangeal syndrome is reported. Abnormally thin hairs were present on the scalp of this patient. Microscopic measurements of scalp hair bulbs disclosed a relative hypoplasia of the dermal papilla which was inserted into a well-developed hair matrix. These findings illustrate that a dermal defect may significantly modulate epithelial differentiation.

ISSN:1018-8665    

DOI:10.1159/000249915

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Comparative results between positive patch tests found during the periods 1968–1974 and 1975–1981 are presented. The number of sensitised patients to nickel, chromate and Peru balsam has significantly increased. On the other hand, the number of turpentine-oil-positive patch tests has strongly decreased. This mirrors the drop in the imported quantities of this product. A schema concerning factors influencing the apparent allergenicity is gi

ISSN:1018-8665    

DOI:10.1159/000249916

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A case of hereditary, circumscribed, palmoplantar keratoderma was reported. Histologically, remarkable orthokeratotic hyperkeratosis was observed, which stained rather basophilic and more translucent than the normal stratum corneum. The stratum granulosum was not present except in the epidermis of the acrosyringium, but the nucleus completely disappeared during the keratinization process and no Feulgen-positive DNA was found. The disappearance of the nucleus did not synchronize with the formation of keratohyalin granules during the keratinization process. Electron microscopically, there were no electron-dense interfilamentous substances, but the marginal band formation occurred normally and the intercellular substances were found.

ISSN:1018-8665    

DOI:10.1159/000249917

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A patient with recessive dystrophic epidermolysis bullosa who developed multiple squamous cell carcinoma involving both hands at the age of 24 is presented. We think this is an interesting case because of its clinical expressiveness and the difficulties in its treatment. The precociousness of development of the tumoral lesions in our patient and the rarity of the complication, were also remarkable and prompted us to report this case.

ISSN:1018-8665    

DOI:10.1159/000249918

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

An instance of perforating granuloma annulare was observed in a 42-year-old female patient in which the necrobiotic material in the dermis was eliminated by a hair follicle. This had previously been described by the author in only 1 other case of perforating granuloma annulare. Transepithelial elimination may occur by the transepidermal and/or transfollicular route. Both pathways are possible in perforating granuloma annulare. Some factors are discussed which may be responsible for the predominance of one route over the other in various disorders of transepithelial elimination.

ISSN:1018-8665    

DOI:10.1159/000249919

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

13 patients with distal subungual onychomycosis in a total of 48 dermatophyte-infected nails were treated with chemomechanical, partial nail avulsion followed by topical miconazole for 8 weeks. On examination, 6 months after cessation of therapy, 42% of the nails were cured by clinical and mycological criteria. The therapeutic response was related to the pretreatment extension of subungual hyperkeratosis. Periungual skin irritation was common during the initial avulsion period. Miconazole solution was well tolerated and this treatment modality proved to be a valuable alternative to other remedies for the treatment of onychomycosis limited to a few number of nails.

ISSN:1018-8665    

DOI:10.1159/000249920

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

In 51 patients with acne vulgaris and 34 patients suffering from occupational oil acne the clinical effect of orally administered tetracycline was evaluated before, during and after a 3-monthly treatment (total dose of antibiotic: 1st month, 28.5 g; 2nd and 3rd months, 15.0 g). Patients treated with placebo were used as controls. Investigations of the skin fluorescence under Wood’s light were performed during the treatment period. In one half of the patients with acne vulgaris and oil acne oral treatment with tetracycline had a very good clinical effect. The purpose of this investigation was the comparison of the results of the treatment of acne vulgaris and occupational oil acne with tetracyclin

ISSN:1018-8665    

DOI:10.1159/000249921

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The case of a patient with mixed-type cryoglobulinemia and cutaneous necrotizing vasculitis, who later suffered from relapsing polychondritis affecting the auricle and the nose, is described. To the best of our knowledge, this combination is unique.

ISSN:1018-8665    

DOI:10.1159/000249922

出版商:S. Karger AG    

年代:1982

数据来源: Karger