摘要:

The effects of laser irradiations have been estimated both from the clinical point of view (rate of reduction of the ulcerated area) and in ultrastructural terms. The modification produced by laser in human fibroblasts in culture have also been investigated. Under our clinical and experimental conditions, laser stimulates the secretion of fibroblasts, both in vivo and in vitro, for reasons that are still the object of research. After irradiation the formation of periodic collagen fibrils is not observed, so that complete ‘restitutio ad integrum’ of the dermal matrix does not oc

ISSN:1018-8665    

DOI:10.1159/000249691

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Histopathological studies were conducted on skin biopsies of 4 patients with the reticular erythematous mucinosis (REM) syndrome. The diagnosis was made on the basis of the clinical picture in 3 of the cases and from histological characteristics in the 4th. These morphological studies were done parallel with a study of skin biopsies with quite a similar histological picture but in which the clinical picture clearly indicated differing entities. The nosologic place of REM syndrome is questioned and the impression arises that there is a clear-cut histogenetical connection with several inflammatory skin diseases.

ISSN:1018-8665    

DOI:10.1159/000249692

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

We report the case of a patient suffering from mycosis fungoides and plasma cell myeloma. It is postulated that this is not a fortuitous association, but that the B cell neoplasm evolved under the sustained inducer stimulus of the malignant T lymphocytes. This hypothesis is suggested by the demonstration of the helper phenotype of the cutaneous lymphocytes associated with a predominance of helper lymphocytes in blood.

ISSN:1018-8665    

DOI:10.1159/000249693

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

A case of acute cutaneous leishmaniasis is reported in which skin biopsy of the lesion revealed deposits of IgM, fibrinogen and C3 in the blood vessel wall and granular deposits of IgG and C3 at the dermoepidermal junction. No immune complexes were detected in the healthy unaffected skin in the same patient and no circulating immune complexes were found in the blood. This case demonstrates tissue-bound immune complexes in cutaneous leishmaniasis.

ISSN:1018-8665    

DOI:10.1159/000249694

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

52 patients with a clinical diagnosis of verruca plantaris were entered into a randomised study of acyclovir cream versus placebo cream versus liquid nitrogen. 47 completed the initial 8-week assessment period. At first, liquid nitrogen was used as a positive control but after the entry of 33 patients it was discontinued as an initial therapy in order to obtain maximal numbers of patients on the cream treatments. At the end of the 8-week assessment period 5 of 18 (placebo cream), 7 of 18 (acyclovir cream) and 1 of 11 (liquid nitrogen) patients were completely cleared of their plantar warts. Patients who failed to clear on cream or liquid nitrogen treatments after the initial assessment period but who wished to continue therapy were subsequently treated with liquid nitrogen. Of a total of 27 patients treated vigorously with liquid nitrogen, for periods of time ranging from 2 to 34 weeks, only 11 were completely cleared of their warts at the end of the study. It is concluded that liquid nitrogen should not be considered as a routine treatment for plantar warts and that acyclovir cream is no better than placebo in the treatment of this condition.

ISSN:1018-8665    

DOI:10.1159/000249695

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Thalidomide alone (200–300 mg daily) or associated with colchicine (2–3 mg daily) was given orally to 25 patients with aphthosis: 8 patients with recurrent oral aphthae; 4 patients with recurrent mucocutaneous aphthosis, without visceral involvement, and 13 patients with Behçet’s disease (Touraine’s aphthosis). A major improvement was noted in all groups, with a rapid healing of mucous lesions and a rapid reduction of pain and burning as compared to prior spontaneous regressions. No new outbreaks were noted at a dose of 50–100 mg thalidomide and 1 mg colchicine daily. Under oral administration of the drugs, thrombophlebitis was noted in 1 case (third group) only. In the other patients with Behçet’s disease, skin aphthae, ocular symptoms, arthritis, superficial nodular phlebitis quickly disappeared with treatment. The efficiency of the drugs is only temporary, since new lesions usually appeared a few weeks after the end of treatment. Due to the relatively small number of cases studied in each group, no conclusions can be drawn concerning the efficiency of thalidomide alone compared to the association of the two drugs. However, this open trial does support the usefulness of thalidomide, or thalidomide and colchicine, in recurrent mucocutaneous aphthae, aphthosis and Beh

ISSN:1018-8665    

DOI:10.1159/000249696

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

We describe a pruritic rash that appears to be associated with pediculosis capitis. We suggest calling it ‘pediculid’ since it appears to be an -id reaction to pediculosis capi

ISSN:1018-8665    

DOI:10.1159/000249697

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

An otherwise healthy 6-year-old girl, with lesions which clinically and histopathologically corresponded to the rare inherited disorder ichthyosis hystrix, is described. The classification of this disorder is briefly discussed.

ISSN:1018-8665    

DOI:10.1159/000249698

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

An ulcerous, infiltrating, mostly solid, partly cystic and keratotic type of basal cell carcinoma of the left palm, of about 5-years duration, in a 60-year-old woman is described. Light and electron microscopical findings are presented with some histogenetical considerations of the tumor.

ISSN:1018-8665    

DOI:10.1159/000249699

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

30 patients with acne vulgaris were treated topically with motretinide 0.1% vanishing cream or benzoyl peroxide 5% gel in an open study. Good results were obtained in both groups. Benzoyl peroxide caused local irritation in 73% of the patients, whereas motretinide was well tolerated except in 1 case. Motretinide is considered an alternative in the treatment of papulopustular acne in young adults.

ISSN:1018-8665    

DOI:10.1159/000249700

出版商:S. Karger AG    

年代:1984

数据来源: Karger