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1. |
Pompholyx: A Still Unresolved Kind of Eczema |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 241-242
C. Crosti,
A. Lodi,
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ISSN:1018-8665
DOI:10.1159/000247360
出版商:S. Karger AG
年代:1993
数据来源: Karger
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2. |
Unstable Phenotypes and Unstable DNA: A Relationship? |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 243-244
H. Traupe,
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PDF (866KB)
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ISSN:1018-8665
DOI:10.1159/000247361
出版商:S. Karger AG
年代:1993
数据来源: Karger
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3. |
Regression and Disappearance of Clinical Symptoms in Some Cases of Genodermatoses |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 245-247
T. Salamon,
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摘要:
Genetic skin diseases are usually thought of as stable phenotypes caused by a mutant gene. However, a review of the literature on genodermatoses and my personal experience with a number of these disorders show that the concept of a stable phenotype is not always true. A number of genodermatoses actually show a regression of symptoms. Among these are monilethrix, several types of erythrokeratoderma, several forms of palmoplantar keratoderma such as the varians Wachters type and the Richner-Hanhart syndrome, and some forms of epidermolysis bullosa, for example the Dowling-Meara type. Three different reasons possibly underlying the regression of symptoms in genetic diseases are briefly discussed: (1) environmental factors, (2) hormonal influences and (3) movable, transposable elements causing instability of the genome.
ISSN:1018-8665
DOI:10.1159/000247362
出版商:S. Karger AG
年代:1993
数据来源: Karger
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4. |
Generalized Eczematous Skin Rash Possibly due to HMG-CoA Reductase Inhibitors |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 248-252
M. Krasovec,
P. Elsner,
G. Burg,
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摘要:
We report on 3 patients who developed a generalized eczematous skin rash under treatment with simvastatin and pravastatin for hypercholesterolemia. These drugs are 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors and suppress cholesterol synthesis in the liver. Based on experimental data from the literature that showed eczematous changes in mice treated topically with the HMG-CoA reductase inhibitor lovastatin, we suspect that the rash observed in our patients may be a consequence of skin barrier dysfunction following inhibition of cholesterol biosynthesis.
ISSN:1018-8665
DOI:10.1159/000247363
出版商:S. Karger AG
年代:1993
数据来源: Karger
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5. |
Treatment of Closed Comedones – Comparisons of Fulguration with Topical Tretinoin and Electrocautery with Fulguration |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 253-257
W.W. Bottomley,
J. Yip,
H. Knaggs,
W.J. Cunliffe,
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摘要:
Two consecutive studies were performed with the aim of clearly defining the optimal physical treatment for closed comedones. The first 10 patients with clinically significant numbers of facial comedones were treated with fulguration under EMLA® anaesthesia on one side of the face and topical tretinoin on the opposite side. At the end of the study fulguration was shown to be significantly (p = 0.005) superior to topical tretinoin. A direct comparison of light electrocautery using EMLA anaesthetic with fulguration without anaesthesia was then performed on 12 patients. The comedones were subdivided by size into those that were approximately 1 mm or less in diameter and those of greater dimensions. In the treatment of larger comedones electrocautery was shown to be significantly superior to fulguration (p = 0.025), but there was no significant difference in the efficacy of the treatments for the smaller lesions
ISSN:1018-8665
DOI:10.1159/000247364
出版商:S. Karger AG
年代:1993
数据来源: Karger
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6. |
General Practitioners’ Workload after Skin Cancer/Melanoma Screening Clinics in the Netherlands |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 258-260
F.H.J. Rampen,
P.J.M. Berretty,
B.E.W.L. van Huystee,
L.A.L.M. Kiemeney,
C.H.H.M. Nijs,
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摘要:
We studied the workload of the general practitioner after two skin cancer screening clinics in the Netherlands. Thirty-one physicians participated in the project. The numbers of patients presenting with benign and malignant skin lesions were recorded 2 weeks before and 6 weeks after the public campaigns. In the week immediately after the screenings there was a small increase in the number of consultations for suspected skin cancer. Thereafter, the weekly number of malignant lesions decreased to precampaign levels. Subsequently to the campaigns the numbers of referrals for benign skin lesions decreased slightly. We conclude that the extra workload for the general practitioner generated by the screening campaigns has been negligible.
ISSN:1018-8665
DOI:10.1159/000247365
出版商:S. Karger AG
年代:1993
数据来源: Karger
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7. |
Acquired C1 Inhibitor Deficiency Revealing Systemic Lupus erythematosus |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 261-263
S. Ochonisky,
L. Intrator,
J. Wechsler,
J. Revuz,
M. Bagot,
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摘要:
We report the case of a previously healthy 54-year-old woman, without any family history, who developed an angioneurotic edema with acquired C1 inhibitor deficiency and systemic lupus erythematosus. The search for a lymphoproliferative disorder was negative. Hydroxychloroquine therapy induced simultaneous resolution of lupus and angioedema. The pathophysiology of this association is discussed.
ISSN:1018-8665
DOI:10.1159/000247366
出版商:S. Karger AG
年代:1993
数据来源: Karger
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8. |
Subcutaneous Emphysema and Pneumomediastinum following Dental Extraction |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 264-265
N. Ouahes,
A. Petit,
F. Poirier,
M. Sigal-Nahum,
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摘要:
A case of acute subcutaneous emphysema of the lateral region of the neck is described. The patient, a 26-year-old woman, also had radiologic evidence of pneumomediastinum. She completely recovered in a few days under prophylactic antibiotherapy. In this case, subcutaneous and mediastinal emphysema was most probably due to the introduction of air into the soft tissue during dental surgery using compressed air equipment.
ISSN:1018-8665
DOI:10.1159/000247367
出版商:S. Karger AG
年代:1993
数据来源: Karger
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9. |
Chordoma with Multiple Skin Metastases |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 266-268
C. Peramezza,
A. Cellini,
P. Berardi,
S. Benvenuti,
A. Offidani,
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摘要:
We report a case of sacral chordoma with numerous skin metastases. Histologically they show the typical ‘physaliform cells’ expressing simultaneously cytokeratin, S-100 protein, epithelial membrane antigen and vimentin immuno-reactiv
ISSN:1018-8665
DOI:10.1159/000247368
出版商:S. Karger AG
年代:1993
数据来源: Karger
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10. |
Cutaneous Manifestations in Kartagener’s Syndrome: Folliculitis, Nummular Eczema and Pyoderma gangraenosum |
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Dermatology,
Volume 186,
Issue 4,
1993,
Page 269-271
J. Vázquez,
V. Fernández-Redondo,
D. Sánchez-Aguilar,
J. Toribio,
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摘要:
We report the case of a 47-year-old male with Kartagener’s syndrome (KS; situs inversus, bronchitis and sinusitis) who showed three types of cutaneous lesions: recurrent outbreaks of nummular eczema, recurrent deep folliculitis and two episodes of pyoderma gangraenosum. The patient had also IgA gammopathy of undetermined significance. This is the second case of KS associated with cutaneous lesions published so far and suggests that primary ciliary dyskinesia syndromes may have skin symptom
ISSN:1018-8665
DOI:10.1159/000247369
出版商:S. Karger AG
年代:1993
数据来源: Karger
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