摘要:

Hodgkin’s disease and mycosis fungoides are malignancies in which there is abnormal T lymphocyte proliferation. The authors report the occurrence of Hodgkin’s disease and mycosis fungoides in a husband and wife, respectively. This represents another instance of clustering of cases of T lymphocyte malignanc

ISSN:1018-8665    

DOI:10.1159/000251078

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The retinoic acid derivative Ro 10-9359, given orally in maximum daily doses of 100 mg to 15 patients with psoriasis vulgaris, led to clearing of the lesions in 8 patients. The average period of treatment was 9 weeks. In 14 patients side-effects were observed, the most important being palmo-plantar desquamation, shivering, thirst and diffuse hair loss. In 2 patients scaling led to withdrawal. In 6 patients abnormal alkaline phosphatase and glutamic-aspartatic transaminase values, partly transient, developed (glutamic-aspartatic transaminase, p < 0.01).

ISSN:1018-8665    

DOI:10.1159/000251079

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Of 5,033 patients who were seen between 1968 and 1975, 407 suffered from psoriasis (Ps) and 245 from candidosis (Cn). Of these, 38 patients (p < 0.001) had both diseases. In 24 additional families, Ps was found in one member and Cn in another. The relationship of the two diseases is discussed.

ISSN:1018-8665    

DOI:10.1159/000251080

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

An easy and cheap method for culturing Neisseria is developed. The medium for gonococci is prepared as proposed by the producer (BBL, Oxoid, Hoechst). About 8 ml of the medium are poured in sterile air-tight stool tubes of 25 ml volume. Materials to be examined for gonococci are taken from the cervix, ureter or anus and are inoculated on the medium. A small piece (20–30 mg) of the GasPak tablet (BBL) is then deposited in the tube and closed immediately. The GasPak tablet consists of sodium bicarbonate and citric acid which, if they come in contact with humidity, produce Co2 gas. The inoculated tube is then put in an incubator at 37°C for 14–24 h. This method gives a good microbiological result. With the aid of the oxidase reaction the colonies take a brown-black color. For further differentiation of the species the sugar fermentation method is neces

ISSN:1018-8665    

DOI:10.1159/000251081

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Based on an ultramicroscopic investigation of the psoralen plus black light-induced photodynamic reaction in the psoriatic cell, there is evidence that the primary reaction takes place in the nuclei, which possess abundant nucleic acid. This initial reaction is manifested by a large vacuole situated in the nucleus. As the vacuole gradually enlarges, the nucleus becomes an annex to the vacuole, while the cytoplasm of the cell succumbs to the necrobiotic process.

ISSN:1018-8665    

DOI:10.1159/000251082

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The effect of ethanol, phenobarbitone, griseofulvin or chloroquine on 3,4-diethoxycarbonyl-1,4-dihydrocollidine (DDC)-induced porphyria in rats has been studied in experiments lasting up to 40 days. Ethanol, phenobarbitone or griseofulvin given later, in addition to DDC, resulted in a clearly greater porphyrin excretion and liver porphyrin concentration than with DDC alone. Chloroquine at first increased, then decreased porphyrin excretion and liver porphyrin was lowered. No drug without DDC was porphyrogenic.

ISSN:1018-8665    

DOI:10.1159/000251083

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The nickel (Ni) concentrations of blood plasma, urine and scalp hair do not differ between hypersensitive and non-hypersensitive subjects. Those who are occupationally exposed have about ten times the control content of nickel in the plasma, urine and hair, whether hypersensitive or not. During vacations the Ni contents of their plasmas and urines decrease sharply. Oral administration of only 5 mg Ni (as the sulphate) increases the Ni concentration of plasma and urine to ten times the normal for more than the subsequent 24 h.

ISSN:1018-8665    

DOI:10.1159/000251084

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Two patients in whom transient paralysis complicated cutaneous herpes zoster infection are described. The major features of this condition are reviewed.

ISSN:1018-8665    

DOI:10.1159/000251085

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000251086

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000251087

出版商:S. Karger AG    

年代:1977

数据来源: Karger