摘要:

According to their susceptibilities to antihistamines, diethylcarbamazine, and colchicine, 6 types of cutaneous anaphylaxis in the rat were characterized. (1) The ACA reaction was highly sensitive to antihistamines and diethylcarbamazine but almost insensitive to colchicine. (2) The homologous PCA reaction by the ‘early’ antibody was almost completely inhibited by antihistamines but little affected by colchicine. This reaction was also significantly suppressed by diethylcarbamazine. (3) When sensitization was made with the intradermal injection of the homologous hyperimmune antiserum, the PCA reaction was insensitive to any of antihistamines, colchicine, and diethylcarbamazine. (4) When local sensitization was made using the heterologous antiserum, the PCA reaction was depressed by colchicine but not by antihistamines or diethylcarbamazine. (5) When the rats were generally sensitized by the intravenous injection of the homologous hyperimmune antiserum, the PCA reaction was quite sensitive to antihistamines and diethylcarbamazine but not to colchicine. (6) When systemic sensitization was made using the heterologous antiserum, the PCA reaction was highly sensitive to both of antihistamines and colchic

ISSN:1018-8665    

DOI:10.1159/000252390

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

By means of the Slein’s method the serum phosphoglucoseisomerase (PGI) was investigated in 146 cases of various dermatoses. In comparison with the values obtained in 50 healthy subjects, PGI was increased in patients suffering from pemphigus vulgaris, legs angiodermatitis, psoriasis, eczema, urticaria and allergic erythemas. The PGI augmentation was smaller in scleroderma and practically without modifications in chronic lupus erythematosu

ISSN:1018-8665    

DOI:10.1159/000252391

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Contact dermatitis due to gold is a rarity. We saw it on a 28-aged female patient after wearing a golden ring during one and a half year. Patch testing with the ring and sodium aurothiosulfate of very low dilutions and lymphocyte transformationtest gave a positive result. That is the evidence of the allergic character of this case.

ISSN:1018-8665    

DOI:10.1159/000252392

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

A case of a newborn child with extensive congenital absence of epidermis is presented. Following our review of the literature, this appears to be the most extensive case described. Some possible etiological causes of this rare disease are briefly discussed.

ISSN:1018-8665    

DOI:10.1159/000252393

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Excision materials and swabs of skin lesions were microbiologically examined of 178 patients with cutaneous diseases which could be caused by mycobacteria, inclusive of such dermatoses in which you can find a specific granulation tissue in histological examination. Among the clinically as tuberculosis of skin finally diagnosed cases 43 patients showed optimal conditions of investigation. In those cases the proof of mycobacteria succeeded 38 times. Because of the effective profit the microbiological examination must be used for the diagnosis of the tuberculosis of skin in addition to the clinical and histological examination. Possibilities to execute the bacteriological investigation optimally are being described.

ISSN:1018-8665    

DOI:10.1159/000252394

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

To elucidate the sensitization mechanism of allergic contact dermatitis isolation of carrier substances from DNCB-treated epidermis was attempted. The homogenate of the epidermis was found to contain immunogenic substances. One of its subcellular fractions could elicit intense contact hypersensitivity although it contained less amounts of haptenic groups than other fractions. Electron microscopy revealed it to be the microsomal fraction of epidermal cells. Treatment of the fraction with deoxycholic acid caused slight reduction of its immunizing ability.

ISSN:1018-8665    

DOI:10.1159/000252395

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Fourteen patients with sarcoidosis were subjected to intradermal injections of tuberculin, Kveim and lepromin antigen. Lepromin antigen produced a regular, positive, sarcoid reaction. It is postulated that the Kveim reaction represents only a response to the human tissue component and it is possible that sarcoidosis and the sarcoid reaction is an idiosyncratic group reaction.

ISSN:1018-8665    

DOI:10.1159/000252396

出版商:S. Karger AG    

年代:1971

数据来源: Karger

摘要:

Topical application to the guinea pig skin of either ethanol, isopropyl palmitate and n-hexadecane in combination or n-hexadecane and ethanol separately produces characteristic circumscribed hyperplasia of the epidermis. The degree and intraepidermal distribution of these changes can be quantitatively assessed by epidermometric methods. Simultaneous application of topical corticoids leads to an inhibition of epithelial proliferation, the degree of which can likewise be determined epidermometrically. Under appropriate experimental conditions, epidermoplasia inhibition tests furnish quantitative evidence of the antihyperplastic activity of locally applied corticosteroids on the epidermis. This aspect of their overall therapeutic action cannot be evaluated by other test methods.

ISSN:1018-8665    

DOI:10.1159/000252397

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000252398

出版商:S. Karger AG    

年代:1971

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000252399

出版商:S. Karger AG    

年代:1971

数据来源: Karger