摘要:

Immunoglobulin E was determined in 13 patients with cutaneous lymphoma and in 30 patients with parapsoriasis en plaques. 11 out of the patients with cutaneous lymphomas showed mycosis fungoides. In 8 patients with parapsoriasis en plaques serum IgE was elevated. These patients revealed signs of the premalignant form of parapsoriasis en plaques. In mycosis fungoides elevated IgE is common, but normal levels are found, too.

ISSN:1018-8665    

DOI:10.1159/000250323

出版商:S. Karger AG    

年代:1980

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250405

出版商:S. Karger AG    

年代:1980

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250406

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Contact sensitization was achieved with dinitrophenylated autologous lymph node cells killed by hypotonic lysis or sonication as well as live cells. The sensitizing ability of the sonicated cells disappeared after freeze-thawing or heating. The significance of these findings is discussed.

ISSN:1018-8665    

DOI:10.1159/000250324

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

This study was performed in 6 healthy young men under analogous experimental conditions to investigate whether or not the epidermal proliferative activity is influenced by the physiological circadian rhythmicity of cortisol concentration in blood. Every 6 h of total duration of the experiments, blood samples were taken for radioimmunoassay of serum cortisol and skin punch biopsies (upper arm inside) were labelled in vitro by 3H-thymidine. In 4 out of 6 individuals, an inverse and time-shifted correlation between the combined serum cortisol levels and the epidermal 3H-LI could be found, i.e., a rise or decline of serum cortisol were followed by a lowered or elevated rate of epidermal LI 6 h later. In particular, a steep increase of serum cortisol from midnight to 6 a.m. correlated to a decrease of 3H-LI from 6 a.m. to noon. This indicates that in man the rate of the epidermal proliferative activity inversely depends, apart from other mechanisms of regulation, on the concentration and circadian periodicity of endogenous cortisol in blood. However, we failed to demonstrate a clear circadian rhythm of the epidermal proliferation, possibly due to the short duration of the experiments extended in each individual to 48 h only.

ISSN:1018-8665    

DOI:10.1159/000250325

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

In a double-blind trial on 44 patients having lichen planus, 500 mg griseofulvin-FP daily for 8 weeks produced significantly better results compared to a placebo. The clinical improvement was accompanied by corresponding histological changes.

ISSN:1018-8665    

DOI:10.1159/000250326

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Calcification of the skin could not be demonstrated in 60 skin biopsy specimens, selectively obtained from 30 chronic hemodialysis patients; 21 of these patients had metastatic calcification at other sites. These results support the proposed rarity of metastatic skin calcification in patients with chronic renal failure. The cause of this phenomenon is not precisely known.

ISSN:1018-8665    

DOI:10.1159/000250327

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

A new occupational disorder characterized by skin sclerosis is described. This disease developed acutely in workmen exposed to the vapor of epoxy resins. Based on animal experiments, an amine [bis(4-amino-3-methyl-cyclohexyl) methane] is suspected of being the causative agent of the skin sclerosis.

ISSN:1018-8665    

DOI:10.1159/000250328

出版商:S. Karger AG    

年代:1980

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250409

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

A case of local hyperhidrosis at the ulnar aspect of the left forearm-carpal region with exacerbation, especially during summer, is presented. The sweat function is normal on the remainder of the body. This case is rare, and few similar cases are known in the literature. The possible pathogenetic mechanisms are discussed.

ISSN:1018-8665    

DOI:10.1159/000250329

出版商:S. Karger AG    

年代:1980

数据来源: Karger