摘要:

A transient dermatologic abnormality which gave a histologic picture compatible with malignant lymphoma is described. The clinical manifestations included diarrhea, hepatosplenomegaly, moderate lymph node enlargement without histopathological changes and evidence of involvement of the reticulo-endothelial system. Both the dermatologic and gastrointestinal disorders appeared approximately 1 year after discontinuation of treatment with diphenylhydantoin, which the patient had taken for 2 years. The possible association between the transient abnormality and the previous diphenylhydantoin therapy justifies the classification of this case as ‘pseudolymphoma syndrome

ISSN:1018-8665    

DOI:10.1159/000250987

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Five contact antiphlogistics were evaluated and compared to hydrocortisone by the human skin vasoconstriction assay in 20 volunteers. The test concentrations ranged from 10––2 to 10––6 w/w; the duration of occlusive application was 16 h. The substances could be ranked as follows in ascending order of a

ISSN:1018-8665    

DOI:10.1159/000250988

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Samples of normal human dermis of different ages are reduced with tritiated sodium borohydride and changes of major reducible cross-links are compared as a function of chronological age. While lysinonorleucine practically remains constant, reduced desmosine changes slightly, hydroxylysinonorleucine and dihydroxylysinonorleucine display a marked decrease with age. An unknown compound is shown to increase with aging. The data suggest a correlation between the change of aldimine cross-links and the structural and/or biochemical changes occurring with increase in age.

ISSN:1018-8665    

DOI:10.1159/000250989

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

A case with a hyperkeratotic form of porokeratosis Mibelli is reported. The clinical characteristics were a nonfamilial occurrence, hyperkeratotic verrucous plaques with an erythema and a segmental distribution. The histopathology showed cornoid lamellae and additional atypical findings. By electron microscopic study Civatte bodies and other degenerated epidermal cells were clarified.

ISSN:1018-8665    

DOI:10.1159/000250990

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

A male patient with unusual clinical features of dermatitis herpetiformis is reported. The eruption consisting mainly of erythematous papules developed symmetrically around the mouth and later around the eyes, and has been circumscribed within these areas for 4 years. The dermatitis herpetiformis nature of the lesion was confirmed by direct immunofluorescent testing.

ISSN:1018-8665    

DOI:10.1159/000250991

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Our procedure for treating psoriatic variants – psoriasis pustulosa generalisata (PPG) and psoriasis erythrodermica (PE) – was based on the following points: (a) to quickly obtain a good tolerance level to photochemotherapy (PUVA) by applying corticosteroids and/or methotrexate (MX); (b) to discontinue the application of systemic drugs with the help of photochemotherapy, and (c) to maintain the improved condition by applying radiation in gradually prolonged intervals, thus enabling the biologic forces of the organism to participate, undisturbed by drugs, in the healing process. In some PE cases, sole PUVA therapy was sufficient, while in others small doses of MX were added to maintain the improved condition. In PPG, skin manifestations completely disappeared and general symptoms were calmed in the first application of this combined therapeutic procedure. However, in the later relapses PUVA had little share in such a combined treatm

ISSN:1018-8665    

DOI:10.1159/000250992

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The author presents a case of early haemachromatosis with skin changes, endocrinological disturbances, circulatory symptom and upsets of the alimentary tract treated by blood letting with good results.

ISSN:1018-8665    

DOI:10.1159/000250993

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250994

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250995

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250996

出版商:S. Karger AG    

年代:1977

数据来源: Karger