摘要:

Comparative in vivo examinations of skin (cutaneous pathergy test, skin window technique over 24 h according to Rebuck) were carried out in 12 patients with Behçet’s disease (BD) and in 13 healthy volunteers serving as controls. 10 out of 12 patients at active phases of BD showed a positive papular (-pustular) skin reactivity to needle prick or vene puncture. These 10 patients simultaneously revealed an increased chemotactic activity of polymorphonuclear leukocytes (PMNL) in vitro. In the controls all pathergy tests were negative and chemotaxis of PMNL was within normal range. The proportion of PMNL initially coming up to 100% in the skin window preparations, very rapidly decreased in patients with BD as compared to a distinctly slower drop in the controls. Conversely to the number of PMNL, the skin window cellular pattern was built up by monophagocytic cells replacing the PMNL. The phenomenon of ‘rapid depletion of PMNL’, from skin window can be considered an additional hint on the functional disturbance of the PMNL involved in the pathogenesis

ISSN:1018-8665    

DOI:10.1159/000249548

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Cultures on Sabouraud medium from the leg ulcers of 50 patients were obtained: 24% of the lesions were infected by Candida species. The risk factors are analyzed. The disappearance of the yeasts after topical treatment does not consistently speed up the healing.

ISSN:1018-8665    

DOI:10.1159/000249549

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Two similar cases of disseminated infection by Neisseria gonorrhoeae were observed at the same time. The patients presented with fever, arthralgy, tenosynovitis, cutaneous pustules of the extremities. In one case, N. gonorrhoeae has been recovered from vaginal discharge; in the other, bacteriological investigations failed. From a review of the literature, it appears that: (1) acral vesiculo-pustular lesions and tenosynovitis represent the most suggestive signs of the disease; (2) it is obviously important to repeat the bacteriological investigations; (3) biological data, included serology, are useless. However, immunofluorescence techniques might detect altered germs in the skin.

ISSN:1018-8665    

DOI:10.1159/000249550

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

Atypical measles with high fever, pneumonitis, erythemato-papular and pustular rash occurred in a 16-year-old girl who had been vaccinated with the inactivated (killed) virus 15 years ago.

ISSN:1018-8665    

DOI:10.1159/000249551

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

A Stewart-Treves angiosarcoma (Stewart-Treves syndrome) developed 14 years after mammectomy (Halsted) and radiotherapy for breast cancer in a woman now 56 years old. Limited excision, graft and complementary radiotherapy have controlled the disease for 20 months. The microscopical and ultrastructural features of this angiosarcoma are presented and the last advances in immunopathology briefly commented.

ISSN:1018-8665    

DOI:10.1159/000249552

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

A 90-year-old female presented with multiple nevoid basal cell epitheliomas, skeletal defects and jaw cysts. The syndrome is briefly revisited.

ISSN:1018-8665    

DOI:10.1159/000249553

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The authors report a new case of induced pemphigus: a 64-year-old man has had rheumatoid arthritis for 10 years. When he developed his pemphigus, he had been taking D-penicillamine and piroxicam for about 8 months. He needed high doses of prednisolone associated with azathioprine to clear his eruption. The case had a fatal outcome.

ISSN:1018-8665    

DOI:10.1159/000249554

出版商:S. Karger AG    

年代:1985

数据来源: Karger

摘要:

The case of a 70-year-old man with squamous cell carcinoma on the glabella which markedly responded to intralesional injections of oil bleomycin (to a total dose of 115 mg) is reported. Adverse reactions to oil bleomycin comprised fever of 37–38°C immediately after injection, local redness, and swelling and induration of 1–2 months’ duration in the marginal area of the injection site. Biopsy of the induration revealed oleogranuloma. The advantages of oil bleomycin are that this dosage form of bleomycin is not accompanied by severe systemic toxicities such as pulmonary fibrosis and that the effective dose is smaller than that of aqueous ble

ISSN:1018-8665    

DOI:10.1159/000249555

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000249556

出版商:S. Karger AG    

年代:1985

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000249557

出版商:S. Karger AG    

年代:1985

数据来源: Karger