摘要:

The prognosis for malignant melanoma is dependent on the stage of the disease, sex, size respectively depth of penetration, structure (lentigo maligna melanoma, superficial spreading melanoma, nodular melanoma), location and age of the patient when the disease begins. The method of conventional treatment (X-ray then excision, excision then X-ray, X-ray alone, excision alone) is not important. The decisive factor is early diagnosis (histology) and early treatment (total excision of the tumor). The value of additional immunotherapy and chemotherapy in cases diagnosed early cannot yet be judged. Melanoma is rarer among colored races than among whites, and the frequency of the disease among Caucasians increases as one approaches the equator. Morbidity and mortality are rising throughout the world. The influence of factors such as trauma and sunlight is disputed.

ISSN:1018-8665    

DOI:10.1159/000250969

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

The results obtained with low-dosage treatment with 2 mg cyproterone acetate and 0.05 mg ethinyl estradiol in 10 women with moderate to severe acne are reported. Eight of these patients showed a very good response, one a moderate response, and one showed no improvement after 3 months. In four patients the administration of antibiotics could be discontinued, and in most of the other patients the dose could be reduced. Three patients discontinued this treatment, two because of side effects and one because of lack of improvement.

ISSN:1018-8665    

DOI:10.1159/000250970

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Two groups of patients with subtotal to universal areate type alopecia were serially treated, 6 with intralesional triamcinolone acetonide suspension and 6 with contact irradiation by ultraviolet light from a high-pressure mercury-arc source with a quartz envelope (Kromayer lamp®). The treatment was limited to one half of the scalp while the untreated half served as a control. Triamcinolone acetonide suspension gave in 2 of the 6 treated patients a temporary stimulating effect on hair growth; later, however, hair growth inhibition was noted in 3 patients. Contact irradiation with ultraviolet light from a Kromayer lamp gave in 4 of the 6 treated patients a stimulatory effect upon hair growth, but did not seem to initiate it

ISSN:1018-8665    

DOI:10.1159/000250971

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

This paper describes the cutaneous side-effects which appeared in 5 patients under Lithium medication for manic-depressive disease: 2 cases with facial and dorsal acne, 1 case with generalized pruritus with burning sensations on the tongue and tumefaction of the lips, 1 case with endogenous generalized psoriasis and 1 case with palmo-plantar hyperkeratosis, ichthyosis and associated with euthyroid goitre. The lithium content of the tissues was assayed by flame spectrophotometry of calcinated biopsy material taken from the epidermis, the dermis and the subcutaneous adipose tissue from 4 of our 5 cases. An experimental investigation was carried out in guinea pigs fed with lithium salts during 6 months. The cation was assayed in samples of epidermis, dermis and perirenal adipose tissue. A study of the accumulation of lithium in epidermal, dermal and adipose tissue is thus added to the studies already published regarding the accumulation of this ion in other tissues.

ISSN:1018-8665    

DOI:10.1159/000250972

出版商:S. Karger AG    

年代:1977

数据来源: Karger

摘要:

Allergic contact dermatitis to N-isopropyl-N′-phenylparaphenylenediamine (IPPD) from rubber is far from being exceptional. Out of a total of 56 cases of allergic contact dermatitis to IPPD, 42 were considered as caused by occupational contacts: 17 cases were found in tyre manufacturers, 9 in car-mechanics, 9 in drivers, and 7 in various industrial branches. Out of the 56 cases, 23 also reacted allergically to mercaptobenzothiazole or to tetramethylthiuramdisulphide, or to both of these substances. In a chromatographic analysis of samples of 9 different tyre brands, IPPD was found in 8 case

ISSN:1018-8665    

DOI:10.1159/000250973

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250974

出版商:S. Karger AG    

年代:1977

数据来源: Karger

ISSN:1018-8665    

DOI:10.1159/000250975

出版商:S. Karger AG    

年代:1977

数据来源: Karger