摘要:

The presence of sclerosis-inducing glycosaminoglycan in the skin was confirmed in an experimental skin sclerosis induced by a chemical compound. An experimental skin sclerosis was first produced in the mouse with bis(4-amino-3-methylcyclohexyl)methane. Out of glycosaminoglycans isolated from the slightly changed skin of this experimental skin sclerosis, the one having a heparan sulfate-like structure was able to again induce sclerotic skin changes in another mouse. The chemical composition of this sclerosis-inducing glycosaminoglycan was somewhat similar to that of the scleroderma-inducing glycosaminoglycan isolated previously from the urine of patients with systemic scleroderma.

ISSN:1018-8665    

DOI:10.1159/000250350

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

The number of Langerhans’ cells (LHC) in the prickle cell layer was increased after prick test in patients with Behçet’s disease. LHC came into contact with lymphocytes in the prickle cell layer. Lattice-shaped granules were seen in the mitochondria of

ISSN:1018-8665    

DOI:10.1159/000250351

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Ultrastructural investigation of a case of papular (dermal) lymphoid hyperplasia with eosinophilia revealed in the proliferating tissue rounded inclusion bodies made up of smaller particles which formed within the lysosomal vacuoles and sometimes occupied a large proportion of the cytoplasm. The bodies also occur in the extracellular spaces. Apart from this, groups of mosaic-like particles and concentric bodies with a central core suggesting viral provenance were demonstrated.

ISSN:1018-8665    

DOI:10.1159/000250352

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

A new method of thin-layer chromatography was used for the study of urinary porphyrins in 42 porphyric patients (27 cases of porphyria cutanea tarda (PCT), 5 cases of porphyria variegata, 4 cases of acute intermittent porphyria, 2 cases of hereditary coproporphyria and 4 cases of erythropoietic protoporphyria), 21 of their clinically normal relatives and 5 controls. The results are compared to previously published data and discussed for the diagnosis of the porphyrias. If urinary porphyrin pattern seems sufficiently pathognomonic for PCT, it appears often unable to allow exact diagnosis of the acute porphyrias; faecal studies and sometimes enzymatic determinations are necessary.

ISSN:1018-8665    

DOI:10.1159/000250353

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

In 4 patients with pustular psoriasis plasma zinc determinations were performed during exacerbations and remissions. Very low values were detected with a normalizing tendency during periods of remission.

ISSN:1018-8665    

DOI:10.1159/000250354

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

The sign of Leser-Trélat was observed in a patient with multiple seborrheic keratoses and hemangiomata. The increase in these lesions of the skin preceded the development of a poorly differentiated lymphocytic lymphoma, a type of malignancy which has not yet been reported in association with this sign

ISSN:1018-8665    

DOI:10.1159/000250355

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

A cirrhotic patient with ascites was apparently well managed with diuretics and salt and water restriction for 9 months. A spontaneous bacterial peritonitis (SBP) developed and the patient finally died following septic shock. There were enough findings indicating that SBP in this case had been existing silently for some time. During this period the only apparent manifestation of this complication was a cutaneous pigmentation on the abdomen. It is suggested that pigmentation may be included among other presentations of this frequently silent process.

ISSN:1018-8665    

DOI:10.1159/000250356

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

The cutaneous calculus of 11 patients were examined. Histologically they were classified into three types: the first type, seen in an early lesion, consisted of a basophilic mass; the second type consisted of a mass and various-sized granules; and the third type consisted entirely of granules. Histochemically, the mass contained acid mucopolysaccharides. In the granules neutral mucopolysaccharides were found. There were numerous, vacuolated mast cells and various-sized, calcified amorphous areas evident with electron microscopic examination of an early lesion.

ISSN:1018-8665    

DOI:10.1159/000250357

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

Clinical and histological features of three examples of degenerative collagenous plaques of the hands in Indian housewives have been described in detail in order to focus attention on a hitherto uncommon entity. Household trauma has been incriminated as the precipitating or a triggering factor in these cases.

ISSN:1018-8665    

DOI:10.1159/000250358

出版商:S. Karger AG    

年代:1980

数据来源: Karger

摘要:

In 2 children, both 7 years old, and with an obvious presence of clinical symptoms, the diagnosis of porphyria cutanea tarda was corroborated by the characteristic patterns of urinary and fecal porphyrin excretion. Familial studies allowed us to consider both cases as hereditary.

ISSN:1018-8665    

DOI:10.1159/000250359

出版商:S. Karger AG    

年代:1980

数据来源: Karger