摘要:

Patch test results from 163 patients with leg ulcers and/or chronic venous insufficiency, tested with a modified ICDRG standard test battery and a pharmaceutical test series, are analyzed and compared with the results obtained from a randomly selected control group of patients with eczematous conditions. A sensitization index for the most common contact allergens present in this test series is calculated, and the relevancy of hypersensitivity to specific topical agents is determined.

ISSN:1018-8665    

DOI:10.1159/000250570

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

A 46-year-old female, otherwise healthy, developed erythematous, pseudotumoral nodules, mainly on the hands; biopsies led to the diagnosis of Woringer-Kolopp disease. Anti-anergic chemotherapy with levamisole proved hazardous but, possibly, beneficial. Classification into benign localized, fatal generalized and intermediate disease is briefly commented upon. Differential diagnosis and tumor origin are discussed; while the Merkel cell hypothesis has been recently advanced strong analogies and slight discrepancies with mycosis fungoides advocate the T cell lymphoma theory.

ISSN:1018-8665    

DOI:10.1159/000250571

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Using the ultrasound technique of visualization (grey-scale technique) and a method of ‘water bath’, the authors obtained echograms of plastic indurations of the penis. The echograms can be immediately photographed and interpreted. By their quick, painless and simple performance, without contrast medium and hazardous irradiation, the authors gain an advantage over some other diagnostic meth

ISSN:1018-8665    

DOI:10.1159/000250572

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

Report on a patient with mycosis fungoides, in whom after a long course the disease developed rapidly into a malignant lymphoma of high grade malignancy. The diagnosis was confirmed by cytomorphological and enzyme-cytochemical methods (demonstration of hydrolytic enzymes in cryostat sections, cutaneous smears and cell suspensions extracted from skin lesions), as well as by immunocytological methods (differentiation of lymphocyte sub-populations). In the tumour stage of mycosis fungoides, a polymorphous infiltrate composed of lymphocytoid and monocytoid cells prevailed, while a proliferation of lymphoblastic cells was present in the terminal stage of the disease. These cells showed no longer the properties of mature lymphocytes and differed also in their enzyme-cytochemical pattern.

ISSN:1018-8665    

DOI:10.1159/000250573

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

In a case of pyodermia (pemphigus) vegetans Hallopeau, modern investigations were performed. Direct immunofluorescent (IF) study of specimens taken from verrucous vegetations failed to reveal the presence of IgG deposits in the intercellular spaces as well IgA and IgG deposits at the epidermal-dermal junction. Indirect IF examination of circulating pemphigus antibodies gave a negative result. Histopathological study did not show the presence of acantholysis. The studies which were carried out indicated that pemphigus vegetans Hallopeau should not be associated with the pemphigus group.

ISSN:1018-8665    

DOI:10.1159/000250574

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

An immunohistochemical study has been undertaken on 25 biopsy specimens taken from lichen planus lesions, using antisera against human fibrin, immunoglobulins IgG, IgA, IgM and C3 (BjC/BjA) complement component. The findings of the present research are discussed and evaluated in relation to the problem of the etiopathogenesis of the disease.

ISSN:1018-8665    

DOI:10.1159/000250575

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

The authors made an electron-microscopic observation of intraepidermic vesiculation in pemphigus vulgaris at its early stage, and found that numerous macrophages were invading the cleft located immediately superior to the basal cell layer. They suggest that the formation of cleft, as a preceding stage to the eventual development into intraepidermic vesiculation, is intimately related to the squeezing-in of invasive macrophages among keratinocytes.

ISSN:1018-8665    

DOI:10.1159/000250576

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

A 71-year-old male had a clinically atypical pemphigus (pemphigus herpetiformis), associated with histopathologic eosinophilic spongiosis. This case is discussed and was frequently found reported in iatrogenic pemphigus.

ISSN:1018-8665    

DOI:10.1159/000250577

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

A report on granular cells found in biopsy material is presented. Morphologically identical patterns were seen in a pigmentated granular ‘rankenneuroma’ and in a patient with a morphea of the tongue. The independent development of granular cells in tumorous and nontumorous tissue supports the idea that the so-called granular cell myoblastoma originates from degenerative alterations of Schwann ce

ISSN:1018-8665    

DOI:10.1159/000250578

出版商:S. Karger AG    

年代:1979

数据来源: Karger

摘要:

2 women, 62 and 69 years old, both suffering from rheumatoid arthritis, were treated for 1 and 1½ years, respectively, with penicillamine. Both developed a bullous eruption which according to clinical and histological picture, immunofluorescence studies and to light provocation, as well as in 1 case to antinuclear antibody findings corresponded to pemphigus erythematosus. In spite of treatment with prednisone and azathioprine, they still keep developing bullae

ISSN:1018-8665    

DOI:10.1159/000250579

出版商:S. Karger AG    

年代:1979

数据来源: Karger