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1. |
Pathogenetic Factors in Urticaria in Children |
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Dermatology,
Volume 154,
Issue 2,
1977,
Page 65-72
E. Bonifazi,
C.L. Meneghini,
A. Ceci,
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摘要:
Results of a study in 62 patients with urticaria and 30 controls, all under 12 years of age, are reported. The study involved history taking and assays of immunoglobulins A, G, M, D, E, of complement fractions C3c and C4 and estimation of Cl esterase inactivator activity in the plasma. Acute urticaria is more frequent than chronic urticaria in children, especially in subjects with atopic diathesis; papular urticaria (or strophulus infantum) is particularly frequent in children under 6 years of age and in the male. Assays of plasma immunoglobulins demonstrated selective deficiency of IgA in two and significant reduction of this immunoglobulin in a further three cases. The mean levels of IgE proved normal in chronic urticaria, raised in acute urticaria, and very high in papular urticaria. Complement assays demonstrated, in one case, a reduction of C3c below 60 mg/100 ml, persisting after the disappearance of urticaria.
ISSN:1018-8665
DOI:10.1159/000251034
出版商:S. Karger AG
年代:1977
数据来源: Karger
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2. |
HL-A Antigens in Pustular Psoriasis |
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Dermatology,
Volume 154,
Issue 2,
1977,
Page 73-77
H. Zachariae,
Overgaard Petersen,
Kissmeyer Nielsen,
L. Lamm,
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摘要:
HL-A typing was performed on 97 patients with pustular psoriasis. HLA-B27 was found increased for the combined three subgroups: localized psoriasis of palms and soles, acrodermatitis continua and generalized pustular psoriasis, who were associated with a high incidence of arthritis. These subgroups have this in common with Reiter’s disease indicating a link between the entities. In persistent palmo-plantar pustulosis an increased incidence of HLA-Bw35 was found. HLA-B13, HLA-B17 and HLA-Bw37 which are found markedly increased in psoriasis vulgaris were in acrodermatitis continua, generalized pustular psoriasis and persistent palmo-plantar pustulosis either absent or not increased as compared with the control population. 7 of 30 patients with localized psoriasis of palms and soles had one of these antigens. Our findings confirm that psoriasis vulgaris and pustular psoriasis as such, seem to be different aetiological entities. Some patients with localized psoriasis of palms and soles may be true psoriatics which besides their psoriasis have a tendency to develop a pustular reaction in their palms and soles similar to persistent palmo-plantar pustulosi
ISSN:1018-8665
DOI:10.1159/000251035
出版商:S. Karger AG
年代:1977
数据来源: Karger
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3. |
Studies on Human Semen in Topical Corticosteroid-Treated and in Methotrexate-Treated Psoriatics |
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Dermatology,
Volume 154,
Issue 2,
1977,
Page 78-84
E. Grunnet,
A. Nyfors,
Brogaard Hansen,
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摘要:
Ejaculates were studied from ten men with severe psoriasis treated with topical corticosteroids and from ten similar patients who had received methotrexate therapy from 1 to 9 years. It was not possible to demonstrate any unfavorable effect on the semen quality during the methotrexate therapy. The semen analysis was more frequently found normal (p = 0.04) in the methotrexate treated group, and no specific abnormality was found in spermatozoa of methotrexate-treated patients. Methotrexate therapy to male psoriatics seems safe and in agreement with this no congenital abnormalities have been reported. A remarkable number of the ejaculates had reduced sperm qualities, and it is proposed that this might be due to psoriatic lesions in the genital tract.
ISSN:1018-8665
DOI:10.1159/000251036
出版商:S. Karger AG
年代:1977
数据来源: Karger
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4. |
A Study on Leukocytes Phospholipid Composition in Mycosis fungoides |
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Dermatology,
Volume 154,
Issue 2,
1977,
Page 85-89
J. Capetanakis,
D. Tsambaos,
A. Kalofoutis,
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PDF (1159KB)
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摘要:
Leucocyte phospholipids composition was determined in 16 patients with mycosis fungoides and 20 healthy controls. Statistically significant differences namely, an increase in phosphatidylcholine and diphosphatidylglycerol and a decrease in phosphatidylserine and phosphatidylinositol concentrations between patients and healthy subjects were observed.
ISSN:1018-8665
DOI:10.1159/000251037
出版商:S. Karger AG
年代:1977
数据来源: Karger
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