摘要:

Skin biopsies from three cases of clinically typical ichthyosis linearis circumflexa Comèl with trichorrhexis invaginata and manifestations of atopy revealed characteristic, previously undescribed histological alterations at the active border of figurate lesions: formation of an eosinophilic, PAS-positive material replacing the lamellar stratum corneum

ISSN:1018-8665    

DOI:10.1159/000251520

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

A clinico-statistical analysis of cases with ichthyosis linearis circumflexa and Netherton’s syndrome is presented. It is suggested that ichthyosis linearis circumflexa with trichorrhexis invaginata, Netherton’s syndrome, and ichthyosis linearis circumflexa without hair changes should be regarded as close variants of the same disease proc

ISSN:1018-8665    

DOI:10.1159/000251521

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

In 17 patients with atopic dermatitis and in 17 healthy control persons, rosette-forming T cells from peripheral blood were investigated. The percentage of rosette-forming T cells in atopies was significantly lower (p < 0.0025) than in the control group. In patients with atopic dermatitis there was a significant correlation between IgE serum levels and the number of rosette-forming T cells. Increase in IgE level is correlated to a decrease in the number of rosette-forming T cells. It is suggested that the primary defect in the immunological system in atopies may be found in the thymus- or T-cell-mediated immunological system, and that this defect be characterized by a decrease or lack of T cells with suppressor function for IgE formation.

ISSN:1018-8665    

DOI:10.1159/000251522

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

55 psoriatic patients (including 15 with psoriatic arthritis) and 50 healthy individuals ‘seronegative’ according to standard procedures were investigated employing an immunoadsorption technique. Antiglobulins were only found in psoriatic sera (18.5%). Clinical correlations and current etiopathogenetic hypotheses are discus

ISSN:1018-8665    

DOI:10.1159/000251523

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

A non-dialysable substance capable of increasing the permeability of cutaneous capillaries was detected in 25 out of 29 blister fluids, all the 28 plasma samples of patients with vesiculobullous disorders and 19 out of 20 plasma samples of normal controls. This substance was stable at ––10°C for at least 11 days, but was inactivated by heating at 100°C for 1 h. It had no effect on the isolated guinea pig ileum. The activity in the plasma of contact dermatitis patients was statistically higher than the normal con

ISSN:1018-8665    

DOI:10.1159/000251524

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Eight cases of contact allergy to virginiamycin are reported. In all patients patch tests with fractions of both virginiamycin (factor M and S) and pristinamycin (fraction IA and IIA) were performed. All patients allergic to virginiamycin, reacted also to pristinamycin, factor M and fraction IIA. Chemically, factor M and fraction IIA appeared to be completely identical, implicating that we are dealing with false cross-sensitivity.

ISSN:1018-8665    

DOI:10.1159/000251525

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

25 female patients with shoe dermatitis were studied. The most frequent cause of the sensitization appeared to be chromic salts, which are mainly used in the tanning process in Greece. Rubber sensitivity is the second cause of shoe dermatitis, tending to assume the first position because of the continuous increase in the use of rubber shoes in Greece.

ISSN:1018-8665    

DOI:10.1159/000251526

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Three cases of eosinophilic pustular folliculitis (Ofuji) are reported. The condition is characterized by follicular, tiny red papules with formation of pustules on fairly well-defined, slightly indurated erythematous plaques. The lesions have a tendency to central healing and peripheral extension, and are asymmetrically distributed on the face, the back, the arms, and sometimes the palms and/or soles. The condition proceeds with remissions and exacerbations. Histological features are pustular folliculitis from the ostium to the sebaceous gland, chiefly composed of polymorphs and eosinophiles.

ISSN:1018-8665    

DOI:10.1159/000251527

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

During a 1-year epidemiological investigation of the mucocutaneous leishmaniasis in the endemic area round the Rio Pachitea (Peruvian virgin forest, catchment area of the upper Rio Ucayali), we diagnosed 120 cases of leishmaniasis tegumentaria sudamericana (Espundia). Of these cases 27 were treated at the local tropical medicine clinic at Puerto Inca: 6 of them received stibophen, and 21 of them stibophen, and 21 of them amphotericin B. The treatment of leishmaniasis tegumentaria sudamericana with amphotericin B is discussed in detail. The use of stibophen is confined to fresh skin ulcers, while amphotericin B is the only drug known to date that holds out hope of success in all mucocutaneous and chronic forms of the disease.

ISSN:1018-8665    

DOI:10.1159/000251528

出版商:S. Karger AG    

年代:1974

数据来源: Karger

摘要:

Twenty-three patients with recurrent Herpes simplex have been treated over a period of 4 years (1969–1972) with poliomyelitis vaccine (Sabin’s), given perorally in the dose of 4 drops once a month for 3 months only. In 74% of cases, this treatment resulted in full recovery with no relapse over a follow-up period of 1–4 years. No harmful side-effects whatsoever were noticed in any of the patients. On the basis of these results, it is concluded that the peroral administration of Sabin’s vaccine is a simple, safe and extremely effective method of treating recurrent Herpes simplex in

ISSN:1018-8665    

DOI:10.1159/000251529

出版商:S. Karger AG    

年代:1974

数据来源: Karger