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1. |
Fibroblasts of an Acrogeria Patient Produce Normal Amounts of Type I and III Collagen |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 157-165
L. Bruckner-Tuderman,
A. Vogel,
U.W. Schnyder,
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摘要:
An 11-year-old patient with clinically typical acrogeria is presented. She had wrinkled ‘old-appearing’ acral skin, thin skin on the whole integument, grooved tip of nose, mottled hyperpigmentation of fold regions and thickened dystrophic toe nails. Histologically, the epidermis was flattened, dermis thinned and the connective tissue densely packed with very few cellular elements. Electron microscopic examination revealed partially abnormal collagen fibers with varying caliber, degenerated elastic fibers and dystrophic fibroblasts. The patient’s fibroblasts produced normal amounts of apparently normal type I and III collagen as analyzed after radioactive labeling. Also, the levels of cytoplasmic mRNA for both of these collagens were similar in acrogeria and control
ISSN:1018-8665
DOI:10.1159/000249166
出版商:S. Karger AG
年代:1987
数据来源: Karger
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2. |
Significant Increase of Urinary Low-Sulfated Heparan-Sulfate-Related Protein in Patients with Severe Systemic Scleroderma |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 166-172
M. Kitabatake,
H. Ishikawa,
Y. Uchiyama,
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摘要:
Radioimmunoassay with an antibody produced against urinary low-sulfated heparan-sulfate-related protein was devised and used to screen the heparan sulfate level in the urine of patients with systemic scleroderma. Patients with diffuse scleroderma, and patients also showing polymyositis/dermatomyositis had elevated values, whereas the value in patients with acrosclerotic scleroderma did not differ from that of the control population. In addition, an increase in this protein was associated with the positivity of anti-Scl-70 antibody. These findings suggest an important role for low-sulfated heparan sulfate in the pathobiology of severe systemic scleroderma.
ISSN:1018-8665
DOI:10.1159/000249167
出版商:S. Karger AG
年代:1987
数据来源: Karger
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3. |
Langerhans Cells in Epidermodysplasia verruciformis |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 173-179
Marek Haftek,
Stefania Jabłońska,
Jacek Szymańczyk,
Maria Jarzą;ek-Chorzelska,
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摘要:
T cell defect and anergy to contact sensitizers are characteristic of the depressed cell-mediated immunity in epidermodysplasia verruciformis (EV). In this disease the generalized infection with human papilloma viruses is associated with a high risk of skin cancers. Langerhans cell density was studied quantitatively in lesions and noninvolved epidermis of EV using OKT6 and anti-HLA-DR monoclonal antibodies with indirect immunofluorescence technique. No significant changes were found in apparently normal skin suggesting no primary defect of Langerhans cells in EV. A marked decrease in Langerhans cell number per unit of epidermal volume could be observed in EV lesions. This additional reduction of immunological surveillance at sites of potentially oncogenic human papilloma virus infection may contribute to the increased risk of malignant transformation in EV lesions.
ISSN:1018-8665
DOI:10.1159/000249168
出版商:S. Karger AG
年代:1987
数据来源: Karger
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4. |
Skin Tags: Localization and Frequencies According to Sex and Age |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 180-183
R. Banik,
D. Lubach,
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摘要:
The relevant literature does not contain detailed numerical data about skin tags. We found 46% skin tag carriers in 750 unselected persons (25% males and 21% females). The risk of getting skin tags increases with age. The age of 50, however, seems to be a turning point, at which a stagnation of the increase is observed. The majority of the carriers had no more than 3 tags per localization; the most frequent localization was the axilla, followed by the neck. This study supplies objective data for the evaluation of skin tags as markers for colonic polyps and may provide standard values for future studies.
ISSN:1018-8665
DOI:10.1159/000249169
出版商:S. Karger AG
年代:1987
数据来源: Karger
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5. |
Fixed Drug Eruption Due to Naproxen |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 184-185
L. Habbema,
D.P. Bruynzeel,
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摘要:
A fixed drug eruption due to reported.
ISSN:1018-8665
DOI:10.1159/000249170
出版商:S. Karger AG
年代:1987
数据来源: Karger
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6. |
Paget’s Disease in an Epidermal Cyst |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 186-190
T.J. Stephenson,
D.W.K. Cotton,
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摘要:
A case of Paget’s disease involving both the epidermis of the nipple and an adjacent epidermal cyst is reported. Immunohistochemistry showed similarity between the infiltrating cells in both sites and those of the underlying mammary adenocarcinoma. Epidermal cysts may be involved in a variety of disease processes which affect the epidermis in general and, unless they are subjected to careful histopathological examination, these diseases may be overlooke
ISSN:1018-8665
DOI:10.1159/000249171
出版商:S. Karger AG
年代:1987
数据来源: Karger
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7. |
Société Beige de Dermatologie et de Syphiligraphie Belgische Vereniging voor Dermatologie en Syfiligrafie |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 191-192
P. Geeraerts,
M. Lowy,
G. Achten,
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ISSN:1018-8665
DOI:10.1159/000249172
出版商:S. Karger AG
年代:1987
数据来源: Karger
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8. |
Sclérœdème de Buschke |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 192-193
P. Gheeraert,
J. André,
G. Achten,
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ISSN:1018-8665
DOI:10.1159/000249173
出版商:S. Karger AG
年代:1987
数据来源: Karger
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9. |
Deux cas de chancre mou |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 193-195
M. Platteau,
J. De Maubeuge,
J. André,
G. Achten,
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ISSN:1018-8665
DOI:10.1159/000249174
出版商:S. Karger AG
年代:1987
数据来源: Karger
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10. |
Réticulose de Crosti |
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Dermatology,
Volume 174,
Issue 4,
1987,
Page 195-195
J. Wanet,
R. Regnier,
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ISSN:1018-8665
DOI:10.1159/000249175
出版商:S. Karger AG
年代:1987
数据来源: Karger
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