ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00338.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

The identification of malignant mesothelial cells in cytological smears prepared from serous effusions is still hampered by the lack of features specific for mesothelial differentiation. We examined the diagnostic value of collagen cores within clusters of tumour cells in cytological smears prepared from effusions from 43 patients with malignant mesothelioma and of 62 cases of metastatic adenocarcinoma. In Giemsa‐stained smears collagen cores were detected in 51% of the cases of malignant mesothelioma and in none of the smears with metastatic adenocarcinoma. Using the Azan stain, collagen cores were detected in 64% of the malignant mesotheliomas and 4% of the adenocarcinomas. Immunoelectron microscopy demonstrated that the collagen cores are largely composed of collagen type III fibrils and some elastin embedded in a homogenous extracellular matrix. It can be concluded that the presence of collagen cores within clusters of tumour cells is highly suggestive of mesothelial differentiation and a common finding in malignant mesotheliom

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00339.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

Routine cytological examination and HPV‐DNA probing were performed on cervical cells obtained from 215 pregnant Chinese females. The procedure utilized the specific binding of a mixture of complementary [32P]‐labelled RNA probes to membrane‐bound target HPV DNA types 6, 11, 16, 18, 31, 33 and 35. Positive results for HPV‐DNA were obtained in 11/215 (5%) of the cases. The cervical smears were routinely processed and in 3/215 (1.5%) cases a cytological diagnosis of wart virus infection was made. All three were included in the 11 probe‐positive cases. Using similar molecular biological techniques, pregnant Western females have an incidence of HPV infection of the cervix which is up to five times that of the present series. This is an unexpected finding in view of the fact that the incidence of cervical cancer is higher in Chinese women than Ameri

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00340.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

The slides of fine needle aspiration cytology specimens from 99 cases of cold thyroid nodules with known histology were reviewed and the number of nucleoli per nucleus counted and correlated with the different histopathological groups. Significant differences were observed between benign and malignant thyroid lesions in the number of nucleoli in the cytological material. Lower values were present in nodular goitres and follicular adenomas compared to carcinomas. In benign lesions the majority of nuclei contained one nucleolus and nuclei with two, three or more nucleoli were less frequent than in follicular, papillary, medullary and anaplastic carcinomas. Only one case of follicular adenoma had cells containing three or more nucleoli compared to more than half the cases of follicular carcinoma.

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00341.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

This is a description of some helminths and protozoa found incidentally in routine cytology specimens submitted to this laboratory. Eight different organisms are described together with the case history for each patient. All the specimens were stained with Papanicolaou technique.

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00342.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

The performance of a new ectocervical brush sampler—the Cervex—was compared with the Ayre spatula in 280 paired cervical smears. The Cervex smears were superior in quality of spread, transformation zone sampling in all degrees of cervical patency and in detection of histologically proven epithelial abnormalities, with a false negative rate of 10.9% compared with 20% for the Ayre. Improvement in predictive value was noted in atrophic samples, with increased cellularity and transformation zone representation. Difficulty has been encountered in obtaining adequate samples from the older woman and from those with iatrogenic scarring of the cervix. Although two‐sampler techniques may be used, submission of high quality pancervical material from a single sampler onto one slide is economically and organizationally attractive. The Cervex seems capable of producing such samples and deserves further evaluation for routine scre

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00343.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

A case of monostotic Paget's osteogenic sarcoma initially diagnosed by fine needle aspiration cytology is reported. The value of electron microscopy in this case is emphasized.

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00344.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

We describe a case of peripheral neuroectodermal tumour of the thoracopulmonary region diagnosed by fine needle aspiration cytology. Light microscope examination revealed numerous small tumour cells arranged in large irregular aggregates occasionally delimiting empty vascular‐type spaces or forming rosette‐like structures. Cytologically the tumour cells showed a marked degree of nuclear anaplasia, scanty cytoplasm and long thin cytoplasmic processes. Electron microscopy revealed cells with characteristics of neuroectodermal differentiat

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00345.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0956-5507    

DOI:10.1111/j.1365-2303.1990.tb00346.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY