ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04038.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:Three young men are described in whom a severe, subacute, predominantly motor peripheral neuropathy resulted from the deliberate inhalation of glue vapour. Weakness began after several years of daily glue sniffing and was marked in proximal as well as distal muscles. Muscle wasting was prominent at the time of presentation. Deterioration continued for several weeks after glue sniffing ceased. Peripheral nerve conduction was markedly slow and there was extensive denervation in the muscles. Characteristic changes were seen on sural nerve biopsy. The habit of glue sniffing is now widespread amongst Australian adolescents and this factor should be considered when any young person presents with a peripheral neuropathy. (Aust NZ J Med 1985; 15: 293–299

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04039.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:Five patients developed neurological symptoms during treatment with amiodarone for intervals ranging between five and 40 months. In each case the daily maintenance dose did not exceed 600 mg. The neurological manifestations included gait ataxia, tremor, polyneuropathy, and myopathy. In all five patients, the neurological symptoms were severe and disabling. In one patient with a myopathy, there was no improvement after amiodarone was withdrawn. The neurological side effects of amiodarone may be disabling and are not always reversible with drug withdrawal. Neurological complications may arise during treatment with usual maintenance doses. (Aust NZ J Med 1985; 15: 300–304

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04040.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04041.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:Two patients with persistent myalgia characterised by onset after an ill‐defined systemic illness, marked fluctuations in the severity of the symptoms, and normal neuromuscular examination with the exception of variable muscle tenderness on deep palpation, may have aforme frusteof myalgic encephalomyelitis. Differentiation from psychogenic muscle pain is important in management. Muscle histology revealed non‐specific Type II fibre atrophy. Mitochondrial respiration was assayed polarographically in intact organellesin vitroand revealed a mild depression of State 3 respiration rates with Site I and Site II substrates. (Aust NZ J Med 1985; 15: 305

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04042.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:The use of fibreoptic bronchoscopy with sterile catheter sampling of pulmonary secretions was evaluated in 70 patients with a provisional diagnosis of pneumonia. In 37 patients quantitative analysis of the sterile catheter isolates was performed (colony forming units (CFU) per ml). Potential bacterial pathogens were isolated in 37 patients and in the quantitative analysis, 14 of 22 isolates were grown in counts ≤ 103CFU/ml. Sterile catheter increased the bacterial isolation rate as in only 19 patients blood (2) or sputum (18) cultures yielded the same organisms. Sputum cultures showed a 25% false‐positive rate in patients with no growth from sterile catheter. Quantitative analysis did not yield any further information in patients receiving antibiotics. Atypical or fungal pneumonia was diagnosed in 22 patients, while ten patients had other pathology simulating pneumonia. Sterile catheter sampling of pulmonary secretions at fibreoptic bronchoscopy proved to be a valuable tool in the diagnosis of bacterial pneumonia. (Aust NZ J Med 1985; 15: 309

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04043.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:During the 13 year period 1971 to 1984 there were 38 pregnancies in 21 renal transplant patients at the Johannesburg Hospital. Twenty‐two ended with live births and included two sets of twins; there were nine spontaneous abortions, six therapeutic abortions, and one stillbirth. Maternal complications were mild in the majority but five patients suffered deterioration in renal function, two undergoing transplant nephrectomy as a result of this. There were seven neonatal deaths, including both sets of twins; death was due to prematurity in six and congenital malformation (diaphragmatic hernia) in one. A further infant had congenital pyloric stenosis which was corrected surgically.Pregnancies were analysed according to whether or not their outcome was successful. Those with a successful outcome had less exposure to warfarin during pregnancy (p = 0.0025) and showed a tendency towards lower immunosuppressive doses of prednisone and azathioprine although these did not reach significance.Although these results indicate an unhappy prognosis for both the mother and fetus, two redeeming features are to be noted. Pregnancy outcome improved markedly in the latter years, possibly owing to non‐exposure to warfarin, less immunosuppression, and improvement in neonatal care, and four of the five mothers who suffered deterioration in renal function were notoriously unco‐operative in their medical care.Pregnancy can only be recommended in the transplanted patient who has stable renal function, is compliant in taking of medications, and whose graft is of such age that the immunosuppressive drug dose is minimal. Warfarin should be avoided. (Aust NZ J Med 1985; 15: 320

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04044.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04045.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:We investigated the hypothesis that patients with idiopathic mitral valve prolapse (MVP) have distinctive anthropometric characteristics as part of an ill‐defined connective tissue abnormality. In 100 consecutive patients with MVP identified at echocardiography, 56 women and 44 men (age range 28–78 years), we compared measurements of height, weight, arm span, upper and lower body segments, anteroposterior chest diameter, anteroposterior chest diameter/height index, body mass index, and metacarpal index with those from an age and sex matched control group. We also compared the frequency of thoracic asymmetry in MVP patients and controls. Both male and female MVP patients had lower body mass indices than their controls (p<0.01 and p<0.001, respectively). Women with MVP were lighter than their controls (p<0.001) and the same trend was seen in men (p = 0.14). There were no significant differences with any of the other measurements or in the frequency of thoracic asymmetry. We conclude that patients of both sexes with idiopathic MVP are leaner than control subjects but do not otherwise have a specific bodily habitus or an increased frequency of thoracic cage abnormalities. The findings do not support the hypothesis of an underlying generalised connective tissue abnormality but raise the interesting question of why MVP patients should be lean. (Aust NZ J Med 1985; 15: 326

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04046.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

Abstract:Three cases of reactive arthritis associated withYersinia enterocoliticabowel infection are reported. In one caseY. enterocoliticawas cultured from stools while all three exhibited a significant increase in serum antibody titres toY. enterocolitica.These are believed to be the first reports ofYersiniareactive arthritis in Australia. Synovial membrane biopsy in one case revealed a mixed inflammatory cell infiltrate the appearance of which was quite dissimilar to that of rheumatoid arthritis (RA). Mononuclear cells of the peripheral blood, but not the synovial fluid from another patient had reduced functional activity compared to RA patients as determined by response to phytohemagglutinin stimulation and allogeneic responses. Large numbers of HLA‐DR and acid phosphatase positive macrophages were also found in the synovial fluid of this patient. The reason for joint involvement inY. enterocoliticareactive arthritis is unknown and further work is necessary. (Aust NZ J Med 1985; 15: 331–3

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1985.tb04047.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY