ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03552.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Ammonia is quantitatively the major buffer for hydrogen ion in the urine. Further, the excretion of ammonia can be varied by acid base status and is therefore of homeostatic importance. Acid base status exerts its effect on ammonia excretion both directly and also via an effect on renal ammonia production from glutamine. The mechanism of the effect of acid base status on glutamine deamidation and deamination is uncertain.Apart from its homeostatic role in health and disease alterations in renal ammonia production may assume pathological importance in potassium depletion and uric acid urolithiasis.

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03553.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03554.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:In this brief review, an attempt is made to summaries the renal handling of potassium and factors influencing the excretion of this ion and from these concepts develop a series of theoretical mechanisms which might explain most of the clinical situations in which hyperkalaemia has been observed.

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03555.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03556.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:Research over the last fifteen years has led to the identification of several metabolites of vitamin D, elucidation of their mechanism of action, clarification of the pathogenesis of several metabolic bone diseases, and development of new diagnostic tests and more effective and safe treatment. 1, 25(OH)2D, the most active metabolite, can be regarded as a highly potent steroid hormone, with its formation from its precursors tightly coupled to physiological need by a variety of ionic and hormonal regulating mechanisms.

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03557.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

摘要:

Abstract:In advanced chronic renal failure hypo‐calcaemia can be due to a combination of factors. These include decreased delivery of calcium into the plasma and increased renal tubular leakage of calcium. The secondary hyperparathyroidism that follows the hypo‐calcaemia leads to osteosclerosis, probably by movement of cortical mineral into trabecular bone. In the dialysis population, an atypical and readily identifiable form of osteomalacia sometimes occurs and is probably secondary to a water‐borne

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03558.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03559.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03560.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY

ISSN:0004-8291    

DOI:10.1111/j.1445-5994.1981.tb03561.x

出版商:Blackwell Publishing Ltd    

年代:1981

数据来源: WILEY