摘要:

Abstract:The nails have numerous functions ranging from cosmetic adornment to tools. Their most important function is to splint the soft pulp of the terminal phalanx to aid fine grasp and manipulation, which may be impaired by a deformed or damaged nail. This review of nail diseases begins with an account of the embryology, anatomy, and physiology of the nail. The presentation of the sections of diseases is somewhat arbitrary as there is at present no satisfactory classification of nail disease.

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00795.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:Sarcoidosis is a multisystem disease of unknown etiology that is rerely diagnosed in children. When mass screening is performed, the incidence of the disease in children approaches that of adults with similar demographics. Most childhood cases occur around ages 9 to 15 years, with small clusters of cases occuring in children under age 4 years. The disease in these two age groups has very different clinical features. Children under age 4 have a clinical triad of rash, arthritis, and uvcitis. The classic syndrome in older children involves primarily lungs, lymph nodes and eyes. In older children, constitutional symptoms (fatigue, lethargy, malaise) and pulmonary symptoms (cough, dyspnea) predominate. Mortality in childhood sarcoidosis is about 5%, with long‐term sequelae in 10% to 20%. Early recognition may prevent complications such as blindness, pulmonary insufficiency, and renal impairmen

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00796.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:The Sturge‐Weber syndrome is characterized by angiomas of the leptomeninges overlying the cerebral cortex in association with a facial nevus flammeus. Although frequently included with other neurocutaneous genodermatoses, the syndrome is almost always sporadic in occurrence. The most common associated neurologic abnormality is seizures, which are controlled in more than 50% of patients by the administration of anticonvulsants. Laser therapy is the most promising therapeutic option for cosmetic management of the facial nevus flammeu

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00797.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:The initial features of acute myeloid leukemia in a previously well 10‐year‐old girl consisted of cellulitic lesions on the face and limbs. These lesions subsequently progressed. with superimnosed blistering and pustulation. They were painful and lender. The condition did not respond to systemic broad‐spectrum antibiotic therapy. Skin biopsy showed an intense, dermal neutrophilic infiltrate without additional evidence of infection or leukemic deposits. The culaneous lesions responded promptly to high‐dose systemic corticosteroids, and the leukemia to chemo

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00798.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:Sarcoidosis is rare in young children. and is characterized by skin. joint. and eye changes. Differentiated clinically from juvenile rheumatoid ar‐ thritis (JRA) by milder constitutional symptoms and characteristic joint abnor‐ malities. sareoidosis is confirmed by demonstrating noncaseating granulomas in skin. conjunctival, or synovial biopsies. Recent reports have shown children with features of both sarcoidosis and juvenile rheumatoid arthritis. some with similarly affected family members. We cared for four children with sarcoidosis and severe joint manifestations. Two had a personal or family history of JRA. Three of the four children had ichthyosiform cutaneous manifestations. which may suggest an association between severe joint disease and ichthyosiform changes. Because of the difficulty in making a diagnosis on clinical grounds alone. biopsy of cutaneouslesions is recommended in children with these sympt

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00799.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:A 6‐year‐old boy had numerous episodes of hydroa vacciniforme. Several of these episodes were accompanied by an anterior aveitis with corneal clouding and stellate keratic precipirates. Wearing sunglasses prevented new eye lesions from developing despite recurrences of skin lesions. Phototesting on facial skin revealed reproductin of skin lesions with uhraviolet B but not ultraviolet A. One should be aware of eye involvement inhydroa vacciniforme, and children who experience this form of photodermatitis should have a careful eye examination and be advised to wear protective sunglas

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00800.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:A child with previous lichenoid lesions had bullae refractory to antistaphylococcal antibiotics. Biopsy of a bulla showed histologic changes of bullous lichen planus. Indirect immunofluorescence using the patient's serum on a perilestional bulla biopsy showed positive staining for IgA and IgG in the stratum granulosum and stratum corneum, confirming the diagnosis. The lesions resolved with dapsone treatment.

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00801.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:Follicular atrophoderma has been associated with a variety of findings. In our patient's family the disease was present in the mother and all of her living children. Serotal tongue was also found in all but one child. We think that follicular atrophoderma is probably inherited as an autosomal dominant trait.

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00802.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:A 15‐year‐old boy had a tumor in his right thigh of two years'duration. A diagnosis of endovascular papillary angioendothelioma of childhood was made. This condition was first categorized as a low‐grade malignancy in 1969, and was called malignant endovascular papillary angioendothelioma of the skin in childhood. Microscopically, the neoplasm is characterized by intravascular proliferation with glomerularlike appearance. the cells are small and regular, with avoid or round nuclei, some of them show hyperchromasia and pyknosis. For the superficial form we prefer to avoid the use of the word “malignant” due to the usually good prognosis after surgical

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00803.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY

摘要:

Abstract:We treated a newborn who had congenital herpes simplex virus (HSV) type 1 infection in which extensive skin lesions occurred with no evidence of involvement of other ograns. The correct diagnosis was not made until the fifth day of life, but after effective treatment with intravenous acyclovir this child has remained in perfect health. At his last evaluation at age 18 months, he had no neurologic or ophthalmologic abnormalities. This report should alert pediatricians and dermatologists to the occasinal occurrence of herpes simplex virus infection in apparently healthy neonates and the importance of making an early diagnosis so that death and severe handicap can be avoided.

ISSN:0736-8046    

DOI:10.1111/j.1525-1470.1987.tb00804.x

出版商:Blackwell Publishing Ltd    

年代:1987

数据来源: WILEY