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1. |
Childhood Condyloma Acuminatum: Association with Genital and Cutaneous Human Papillomaviruses |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 101-106
Slavomir Obalek,
Joanna Misiewicz,
Stefania Jablonska,
Michel Favre,
Gerard Orth,
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摘要:
Abstract:We studied 25 children, age 7 months to 12 years 6 months, with anogenltal warts, and their parents. In most children the warts were localized in the anal area, In 3 of 18 girls perianally and on the vulva, and in 4 girls exclusively on the vulva. Southern blot hybridization studies disclosed an association of condylomata with human papllormavlruses (HPV) 6 and 11 in 74% and HPV 2 In 17.4% ol patients. The clinlcal features were similar in warts Induced by genital and cutaneous HPVs. Even the HPV 2‐associated warts in the vulva of two girls were typical of condyloma acuminatum.In all children with HPV 2‐induced condytomata, cutaneous common warts coexisted, also induced by HPV 2. However, three mothers had cutaneous warts, and the children's condylomata were associated with HPV 6. Thus, the mere presence of skin warts in family members does not rule out other sources of infection. Sexual abuse was suspected in four girls and two boys, but was not confirmed in any. Nonsexual transmission could occur by persons with the lesions taking care of children. Perinatal transmission also appears to be an important route of infection In small babies. Infection In utero was probable In one girl in whom anal warts appeared in the first week of life and whose mother had cervical condylomata during pregnancy. This study provides further confirmation of possible nonsexual transmission of genital HPVs and the not infrequent association of childhood condylomata with HP
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00031.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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2. |
Urticaria in Children |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 107-110
Srabani Ghosh,
Amrinder J. Kanwar,
Sorrinder Kaur,
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摘要:
Abstract:The etiologic factors responsible for urticaria were analyzed in 44 children seen In the Urticaria Clinic, a referral center of the Dermatology Department. Of these, 23 were girls and 21 boys. Nine (20.5%) had acute urticaria and 25 (79.5%) were diagnosed as having chronic urticaria. A definitive etiology factor was identified in 1B (40%) patients. Of these, 15 had physical urticarias; in 2 foods and in 1 drug was incriminated. Probable ettologlc factors were identified in 19 (43%) patients, in 5 (11.3%) of whom more than one factor was Identified. In 11 (25%) children, it was not possible to establish the cause. Our study suggests that etiologic factors of urticaria are more readily identifiable in children than in adults.
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00032.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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3. |
Trichothiodystrophy: Ultrastructural Studies of Two Patients |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 111-116
S. Calvieri,
A. Rossi,
B. Amorosi,
S. Giustini,
D. Innocenzi,
G. Micali,
R. Rizzo,
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摘要:
Abstract:An 18‐month‐old and an 8‐year‐old girl had trlchothlodystro‐phy (TTD). Microscopic observation of the hair under polarized light showed typical alternation of bright and dark bands; amlno add analysis of the hair demonstrated a marked reduction of cystine levels. Both patients had skin lesions consisting In the older child of diffuse follicular keratosis since birth, and in the younger of an ichthyosiform darmatitls on the lower legs that appeared at age 4 months. Ultrastructural studies of the skin showed striking similarities in both cases: perinuclear vscuoles with a unit membrane in the keratinocytes, and dispersed, irregularty arranged bundles of tonofilaments particularly at the desmosome junction. The origin of the vacuoles is unknown; the abnormalities of the tonofilaments could be explained on the basis of a generalized abnormality in sulfur‐containing proteins, reflecting a disturbance In the synthesis of keratins. These electron microscopy findings could be considered as a peculiar feature of ichthyotic skin in patien
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00033.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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4. |
Trichothiodystrophy and Associated Anomalies: A Variant of SIBIDS or New Symptom Complex? |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 117-122
Joseph H. Hersh,
Laura R. Klein,
Margie R. Joyce,
Maria K. Hordinsky,
Michael Y. Tsai,
Amy Pafler,
Resa Hyzer,
Robert H. Zax,
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摘要:
Abstract:Trichothiodystrophy is characterized by sparse, short, sulfur‐deflclent hair. Numerous symptom complexes have been described in which the hair abnormaiity represents a constant feature. We report a boy with trichothiodystrophy, ichthyotic skin changes, onychodystrophy, chronic neutropenia, osteoscierosis, hypothyroidism, nystagmus, growth and mentai retardation, and microcephaiy, who developed a progressive encephalopathy with ataxia and optic atrophy at 2.5 years of age. in addition to a deficient cystine ievei identified on a hair sampie, a disturbance in the composition of other amino acids was present. Ai‐though features were reminiscent of osteoscierosis, ichthyosis, brittie hair due to trichothiodystrophy, impaired inteliigence, decreased fertiiity, and short stature (SIBIDS) and couid represent a variant of this disorder, findings in our patient may refiect a new trichothiodystrophy symptom compiex that carries a poor prognosis for survivai beyond chiidh
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00034.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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5. |
Benign Pigmented Apocrine Vulvar Hamartomas |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 123-124
Susan M. Stephens‐Groff,
Ronald C. Hansen,
Jerry Bangert,
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摘要:
Abstract:Pigmented vulvar lesions were observed In a child during a sexual abuse evaluation. Gross examination of the lesions appeared most consistent with bowenoid papulosis; however, biopsy confirmed the le‐sions to be pigmented apocrine hamartomas. To our knowledge, these rare and benign tumors have never been described as pigmented, but should be added to the differential diagnosis of pigmented vulvar lesion
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00035.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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6. |
Erythema Elevatum Diutinum Associated with Celiac Disease: Response to a Gluten‐Free Diet |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 125-128
Mercedes Rodriguez‐Serna,
Jose‐Miguel Fortea,
Amparo Perez,
Isabel Febrer,
Carmen Ribes,
Adolfo Aliaga,
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摘要:
Abstract:An 11‐year‐old girl with a history of Insulin‐dependent diabe‐tes melitus had erythema elevatum diutinum (EED) associated with a ce‐liac disease related to a possible kidney disease. Dapsone did not im‐prove the skin manifestations. However, the tesions disappeared after a gluten‐free diet was begun. To our knowledge, this report describes the first case of EED In a patient with c
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00036.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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7. |
Penile Purpura as a Manifestation of Lichen Sclerosus et Atrophicus |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 129-131
Philip G. Barton,
Michael J. Ford,
Betsy B. Beers,
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摘要:
Abstract:Heightened public and professional awareness of the sexual abuse of children demands that physicians be able to distinguish lesions associated wtth sexual abuse from those caused by primary skin disor‐ders. Purpura to an occasional manifestation of pediatric lichen aderosus et atrophicus (LSA), especially when the vulva is affected. We report a 12‐year‐old boy with penile purpura that occasioned a consideration of sexual abuse but proved to be due t
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00037.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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8. |
Lichen Planus in Children: A Case Report |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 132-135
F. Cottoni,
P. Ena,
G. Tedde,
M. A. Montesu,
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摘要:
Abstract:Lichen planus (LP) Is rare in children. A review of the literature reveals that it has some peculiarities with respect to sex, localization, clinical aspect, race, and family history. We present an Indian child with the documented peculiarities of infantile LP. A comparison of LP and graft‐versus‐host disease points to the Importance of thymic Involution in the pathogenesis of the former, which could explain the rarity of this disorder In infa
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00038.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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9. |
Scabies of the Scalp Mimicking Seborrheic Dermatitis in Immunocompromised Patients |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 136-138
Carols Duran,
Lourdes Tamayo,
Ma. de la Luz Orozco,
Ramon Ruiz‐Maldonado,
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摘要:
Abstract:Two children with acute tymphoblastic leukemia undergoing chemotherapy had a special form of scabies characterized by fine scaling of the scalp simulating seborrheic dermatitis. Pruritus was mild or absent, immunocompromised children and adults should receive whole‐body and scalp antiscabietic treatmen
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00039.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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10. |
Papular Xanthoma in Children: Report and Immunohistochemical Study |
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Pediatric Dermatology,
Volume 10,
Issue 2,
1993,
Page 139-141
E. Fonseca,
F. Contreras,
J. Cuevas,
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摘要:
Abstract:Papular xanthoma was diagnosed in a 14‐month‐old boy. The eruption cleared spontaneously within four years, immunohistopathologic study revealed that the predominant foamy histiocytic cells had the phenotypic features of the dermal dendrocyte. Giant multinucleated cells, which showed characteristics of monocyte‐derived macrophages, were also present. We suggest classifying diseases derived from dermal dendrocytes into a separate group of histiocy
ISSN:0736-8046
DOI:10.1111/j.1525-1470.1993.tb00040.x
出版商:Blackwell Publishing Ltd
年代:1993
数据来源: WILEY
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