11. |
THE LYMPHATIC DRAINAGE OF THE RAT PROSTATE AND ITS STATUS AS AN IMMUNOLOGICALLY PRIVILEGED SITE |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 127-132
WILLIAM NEAVES,
RUPERT BILLINGHAM,
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摘要:
SUMMARYRecent suggestions that the rat prostate is an alymphatic, immunologically privileged site stimulated further investigation of its status using a variety of techniques. Fixation of certain organs by vascular perfusion of glutaraldehyde followed by plastic embedding avoids the distortion and stromal reorganization that often obscures evidence of lymphatic vessels in conventional histological preparations. When applied to the rat prostate, this technique revealed small lymphatic vessels at irregular intervals throughout the sparse stroma. Ink injected into the prostate drained from the organ into iliac lymph nodes within 3 to 4 hr. Enlargement of iliac lymph nodes within 1 week after injection of parental strain lymphoid cells into the prostate of F1rats confirmed the drainage pattern. Ink and lymphoid cell injections into the bladder wall yielded comparable results, although ink reached iliac nodes sooner than it did in prostate injections. Immunological privilege was investigated by determining survival of skin allografts implanted in the prostate. Skin-into-prostate grafts bearing either major or minor histocompatibility antigens were rejected within a few days of similar orthotopic grafts. The inability of the rat prostate to allow significantly prolonged allograft survival as well as its demonstrated lymphatic drainage argues against an immunologically privileged status.
ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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12. |
TRANSPLANTATION OF AUTOIMMUNE POTENTIAL IV. REVERSAL OF THE NZB AUTOIMMUNE SYNDROME BY BONE MARROW TRANSPLANTATION |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 133-135
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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13. |
ACTIVATED LYMPHOID CELLS INDUCE VASCULARIZATION |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 136-138
&NA;,
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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14. |
TRANSPLANTATION OF BONE MARROW IN OUTBRED DOGS WITHOUT GRAFT‐VERSUS-HOST DISEASE USING TOTAL LYMPHOID IRRADIATION |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 139-141
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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15. |
SUCCESSFUL ENGRAFTMENT OF CRYOPRESERVED AUTOLOGOUS BONE MARROW STEM CELLS IN MAN |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 142-144
&NA;,
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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16. |
AZATHIOPRINE IS NECESSARY IN KIDNEY TRANSPLANTATION |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 145-145
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PDF (307KB)
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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17. |
DETERMINING FACTORS IN THE PROLONGATION OF KIDNEY ALLOGRAFT SURVIVAL BY PRETREATMENT WITH CONCANAVALIN A |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 146-148
&NA;,
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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18. |
DARY OF FORTHCOMING EVENTS |
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Transplantation,
Volume 27,
Issue 2,
1979,
Page 149-149
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PDF (79KB)
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ISSN:0041-1337
出版商:OVID
年代:1979
数据来源: OVID
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