摘要:

Vaginal bacterial flora have recently become the focus of intense research attention. Factors contributing to the renewed interest include the role of non-ulcerative sexually transmitted diseases and potentially other forms of vaginitis in heterosexual HIV transmission, vaginal flora of bacterial vaginosis directly leading to obstetric complications and upper genital tract disease, and newly described antibiotic responsive vaginal infections.

ISSN:0951-7375    

出版商:OVID    

年代:1996

数据来源: OVID

摘要:

Increasing awareness of the range of viral pathogens infecting or being transmitted via the genital tract has been accompanied by greater knowledge of the prevalence and natural histories of the most common of these, namely herpes simplex virus and human papilloma virus. Unfortunately, the absence of effective vaccines and the evidence emerging that therapy of herpes simplex virus and human papilloma virus does not completely prevent viral replication causes clinicians much uncertainty in their practical management of patients. Emerging data on the relationship between viral detection in the laboratory, subclinical lesions and the risk of sexual transmission of these viruses is urgently required to unravel this problem.

ISSN:0951-7375    

出版商:OVID    

年代:1996

数据来源: OVID

ISSN:0951-7375    

出版商:OVID    

年代:1996

数据来源: OVID

摘要:

Some progress has been made in understanding the pathogenesis of a number of sexually transmitted diseases. The unique evasion strategies which this group of pathogens utilize make vaccine development particularly difficult. There are considerable efforts now being directed at the possibility of human immunogenicity testing of a gonococcal porin vaccine. While considerable work needs to be done, it appears reasonable thatChlamydia trachomatismajor outer membrane protein may be a future vaccine antigen. The identification of aHaemophilus ducreyitoxin which may play a role in ulcer formation enhances the possibility that an antitoxin type vaccine might be feasible to prevent ulcers. The gD2 herpes simplex vaccine trials have shown promise that recurrent viral infections may be controlled.

ISSN:0951-7375    

出版商:OVID    

年代:1996

数据来源: OVID