ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Heat shock proteins are chaperones to construct protein molecules and are widely distributed in prokaryotic and eukaryotic cells. They are also induced by environmental stress to protect cells. Human heat shock proteins cross-react with bacterial heat shock proteins to modulate immune responses to induce autoimmunity. They are involved in the differentiation and growth of neoplastic cells as well as normal cells. They are also involved in various inflammatory skin diseases and in fibrotic process. Heat shock proteins play important roles in the pathogenesis of many skin diseases.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Only recently have attempts been made to develop techniques for the early identification of scabies infections and to identify the genome of the mites. Most work with scabies employs rudimentary technology and requires skill for accurate diagnosis. Many countries still have no widely available dermatology service to deal with this infection and its sequelae

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Mycobacterium marinumis a saprophytic mycobacteria capable of causing soft tissue infection in humans, usually acquired by inoculation. As with other mycobacterial infections, diagnosis may be difficult and recent developments in molecular biology are also being applied to atypical mycobacteria such asMycobacterium marinum

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Renewed interest in molluscum contagiosum virus has been stimulated by the availability of the entire genomic sequence and the identification of more than 160 putative genes, some of whose functions are now under analysis. Important findings have been generated by the recognition that certain viral proteins have anti-chemotactic and anti-apoptotic properties. Other advances include the characterization of two recombinant immunoreactive proteins, and the publication of the first seroepidemiological survey of the general population. Recent clinical studies indicate that some of the newer antiviral agents and physical treatment modalities offer significant benefits for the treatment of recalcitrant infections in the immunosuppressed.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The majority of recent publications on the immunology ofPropionibacterium acnesrelate to the potential use of the bacterium as an adjuvant or its use in rodent models of human inflammatory disease. These studies have increased the understanding of the potential effects ofPropionibacterium acneson cells of the mononuclear phagocyte system. Research into the immunology of acne and the role thatPropionibacterium acnesplays in inflammatory acne has been limited, with efforts being focussed on the problems ofPropionibacterium acnesresistance to antibiotics. Recent studies have indicated that inflammatory acne is a T cell-mediated disease, but whetherPropionibacterium acnesis the initial stimulus for either the specific or non-specific recruitment of T cells in acne lesions is still a matter for conjecture.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Gram-positive cocci account for the large majority of cases of infective endocarditis. Pathogenesis investigations of endocarditis have therefore focused on purported virulence factors in staphylococci, viridans group streptococci and enterococci. In addition to novel molecular techniques that have been adapted for use in the examination of gram-positive cocci, animal models of experimental endocarditis have been employed to support or discount the role of specific bacterial components in production of infective endocarditis. This review details recent work that addresses endocarditis pathogenesis and highlights pertinent findings from these investigations.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

Acute otitis media is one of the most common causes of medical consultation worldwide, and has a high economic impact. In this review, a clear definition between acute otitis media and otitis media with effusion is presented. The microbiology and characterization of the main bacterial isolates in acute otitis media and the susceptibility patterns are reviewed, and the latest concepts in antimicrobial treatment are discussed. The need for courses that improve the capability of primary care physicians to diagnose acute otitis media using pneumatic otoscopy, and for parental education is also discussed.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

In over 10 years since the definition of superantigens, much has been learned about host cell-superantigen interactions. The initial simple set of rules used to define these interactions has given way to a more complex system, in which the activation of multiple cell types can occur as a consequence of superantigen-cell interactions or as a result of bystander effects based on the induction of a specific cytokine milieu. As a consequence, our ideas concerning the ways in which superantigens might be involved in disease are also expanding rapidly. This review highlights some of the many different pathways of superantigen-associated pathogenesis currently under investigation.

ISSN:0951-7375    

出版商:OVID    

年代:1999

数据来源: OVID