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11. |
Characterization of Mutants of the Vitamin‐D‐Binding Protein/Group Specific Component: GC Aborigine (1A1) from Australian Aborigines and South African Blacks, and 2A9 from South Germany |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 50-54
Andrea Kofler,
Andreas Braun,
Trefor Jenkins,
Sue W. Serjeantson,
Hartwig Cleve,
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摘要:
AbstractThe structure and organization of the human vitamin‐D‐binding protein gene (DBP, group‐specific component, GC) have recently been determined. Each ex‐on may now be amplified by the PCR method using oligonucleotide primers deduced from the intron sequences near their 5′ ends and 3′ ends. In this study we examined the anodal GC variants 1A1 and 2A9. Genomic DNA of the variant 1A1 was obtained from Australian Aborigines and from South African Bantu‐speaking Blacks. Amplification and sequencing of exon 11 of 1A1 revealed a point mutation in codon 429 at the second position. It is remarkable that this mutation was found in the Australian 1A1 variant and in the African 1A1 variant, and raises the question whether the mutation in these two ethnic groups has a common origin. Genomic DNA of the 2A variant called 2A9 was obtained from South Germany and a point mutation also concerning position 429 in exon 11 was found. The nucleotide exchange in this case, however, was at the first position of the codon. The widely distributed genetic polymorphism of DBP/GC is located in exon 11 and is characterized by substitution at amino acid positions 416 and 420. Variant 1A1 is due to a second site mutation of the allele GC*1F; variant 2A9 is due to a mutation in th
ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02545.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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12. |
Transmission of Hepatitis C Virus by Anti‐HCV‐Negative Blood Transfusion: Case Report |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 55-56
H. Vrielink,
C.L. Poel,
H.W. Reesink,
H.L. Zaaijer,
P.N. Lelie,
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摘要:
AbstractAcute posttransfusion hepatitis C was reported in a recipient of 3 units of red cells. The recipient became acutely icteric 6 weeks after transfusion, and HCV infection was diagnosed. Stored serum samples of the 3 implicated donations, which were negative with ELISA‐2, were retested by PCR and 3rd‐generation antibody tests. One implicated donation was PCR positive, but anti‐HCV negative. Both other donations were negative in all tests. The donor was recalled to the Blood Bank 13 weeks after the implicated donation and was found to be ELISA‐3 plus RIBA‐3 positive. Eight months after the implicated donation, the donor is still PCR and RIBA‐3 positive, whereas the recipient became PCR negative but remained anti‐HCV RIBA‐3 positive. The case shows that blood products from donors collected during the open window period of an HCV infection can transmit HC
ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02546.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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13. |
HCV Core IgM and IgG Antibodies in Blood Donors |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 57-58
H.P. Kapprell,
A. Majnak,
G.A. Medgyesi,
J.E. Szabó,
G. Michel,
M. Albrecht,
H. Heyermann,
H. Hampl,
H. Troonen,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02547.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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14. |
Toxic Shock Syndrome after Staphylococcal Pneumonia Treated with Intravenous Immunoglobulin |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 59-60
Makoto Ogawa,
Shiro Ueda,
Naohiko Anzai,
Kazushige Ito,
Masao Ohto,
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PDF (136KB)
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02548.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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15. |
Severe Heat Treatment of Freeze‐Dried Coagulation Factor Concentrates: Is Hotter Necessarily Better? |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 61-62
P.L Roberts,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02549.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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16. |
Prevalence of Antibodies to HTLV‐I/II in High‐Risk Patients and Blood Donors in Denmark |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 63-64
Claus Bohn Christiansen,
Per Wantzin,
Ebbe Dickmeiss,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02550.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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17. |
Anti‐HCV Antibodies and HCV RNA in Libyan Blood Donors |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 65-65
A.‐N. Y. Elzouki,
N.J. Beeching,
K.J. Mutton,
J.A. Garson,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02551.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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18. |
Clinically Significant Anti‐LWabby Monocyte Monolayer Assay |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 66-67
R. Villalba,
P. Ceballos,
G. Fornés,
M. Eisman,
J.L. Gómez Villagrán,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02552.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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19. |
Concerning the Paper of Wang et al.: Lewis Phenotypes in Orientals |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 68-68
M. Lin,
R. E. Broadberry,
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02553.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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20. |
Reply |
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Vox Sanguinis,
Volume 68,
Issue 1,
1995,
Page 69-69
Baojie Wang,
Kazuko Akiyama,
Hiroshi Kimura,
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PDF (80KB)
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ISSN:0042-9007
DOI:10.1111/j.1423-0410.1995.tb02554.x
出版商:Blackwell Publishing Ltd
年代:1995
数据来源: WILEY
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