摘要:

Abstract.Immunogenetic analysis of a homozygous C2‐deficient individual and family members demonstrated linkage of HLA‐A25, B18 and C2°. HLA‐D typing showed that 5 members typed with homozygous Dw2 typing cells from an individual with C2 deficiency but not with Dw2 typing cells from 2 individuals with normal C2. The homozygous C2‐deficient propositus and brother were HLA‐A and B homozygous but heterozygous at the HLA‐D and glyoxalase I loci. Therefore, in this family, the C2° gene is linked with two distinct haplotypes: HLA‐A25, B18, Dw2, GLO1 and HLA‐A25, B18, D unknown, GL02. These results could be explained by an ancestral recombinant event, which occurred between the C2° locus and HLA‐D locus in which C2° segregated with HLA‐B. This would suggest that the locus for the C2° gene maps between HLA‐B and HLA

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02311.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Non‐human primate sera were investigated for the presence of various human immunoglobulin epitopes including allotypes of ϰ‐, γ1‐, γ2‐, γ3‐ and α2‐chains, isotypes of ϰ‐, γ1‐, γ2‐, γ3‐, γ4‐, α1‐, α2‐ and μ‐chains and iso‐allotypes. The non‐human primate sera comprised representatives of several species of apes, Old World monkeys, New World monkeys and prosimians.It is concluded that non‐human primate immunoglobulins have many structural similarities with those of human IgM, IgA and IgG. The extent of these simil

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02312.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Erythrocytes from human blood stored at 5°C in anticoagulant‐preservative solutions are considered, after a period from 21 to 24 days, unsuitable for transfusion. The nonviability of the cells appears due to metabolic impairment accompanied by a change of the biophysical properties of the cell but surprisingly not to a decrease of sialic acid of the membrane. The absence of proteolysis can be attributed to calcium chelation and to the stable levels of plasma protease inhibitors throughout the storage period. In fact, when erythrocytes are incubated for several days at 5°C in protein‐free media, release of sialopeptides from the membrane increases slowly and steadily, particularly if the medium is without glucose and adenine but contains divalent cations. Moreover, this phenomenon is strikingly amplified when incubation in protein‐free media is carried out at 37°C and once the ATP level has fallen below 5% of its initi

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02313.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Polyethylene glycols 4,000 and 6,000 were determined in different plasma protein preparations by the formation of complexes with barium and iodide ions after precipitation of the proteins with perchloric acid. The method, which is fast and reliable, can be used for the determinations of PEG down to 0.005% (w/w) of the total protein content.

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02314.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Anti‐Jsawas found in a Japanese female who had never received a transfusion and had borne 3 Jsa‐negative children. The antibody agglutinated Jsacells suspended in saline and treated with proteolytic enzymes as well as reacting with those cells by the indirect anti‐globulin test. This example is the first reported ‘naturally occurring’

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02315.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02316.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02317.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02319.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Book reviewed in this article:B. Cinader (ed.)Immunology of ReceptorsA. E. Mourant A. C. Kopeć K. Domaniewska‐SobczakThe Genetics of the JewsA. E. Mourant, A. C. Kopeć, K. Domaniewska‐SobczakBlood Groups and Di

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02320.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1979.tb02321.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY