摘要:

Abstract.15 blood coagulation and fibrinolysis variables were determined in 80 healthy blood donors. Males were shown to have significantly higher levels of factor VII and factor X, and in subjects with blood group O significantly lower levels of VIIIR:AG were observed. In individuals with blood group O a skewed distribution of VIIIR:AG suggested a mixed population of this antigenic determinant. No significant correlation (r<0.36) was found between age and any of the laboratory variables.

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02966.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.The American Red Cross collects blood from a number of defined subsets of the donor population and the proportion of blood collected from each subset varies widely from center to center. A large part of the variation in prevalence of HBsAg may be related to variations in the proportion of blood collected from plants and factories, military units and schools or colleges. We have derived a regression equation, significant at the p<0.001 level, which links HBsAg prevalence with these collection parameters. Using this equation, we were able to predict the prevalence of HBsAg among first‐time donors in 6 of the 9 geographic divisions of the United States with an accuracy exceeding 10%. The predictions for the remaining divisions were within 35% of the actual value. Correlation studies were supported by measurements of true donor prevalence in three blood center

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02967.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Serum erythropoietin has been measured before and after transfusion of blood stored in acid citrate dextrose for varying periods of time. A greater fall in erythropoietin was found following the transfusion of fresh blood than after an equal amount of stored blood in which 2,3‐diphosphoglycerate concentrations were depleted. This confirms the expectations that in vivo tissue oxygenation is influenced by the oxygen affinity of transfused bloo

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02968.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Two female newborns were suspected of having been exchanged. Each baby was tested for blood groups ABO, Rh and MN; for isoenzymes ADA, AcP1, GLO, PGM1, AK1and for Hp; and for HLA‐A and B phenotypes. In family 1 the baby girl was excluded on the basis of ADA, GLO, PGM1, AK1, Hp and HLA phenotypes. In family 2 the baby girl was excluded on the basis of Rh, PGM1, Hp and HLA phenotypes. Yet the phenotypes of each girl did fit with the parents of the other family. The odds for the babies to belong to the other families were 6.9 × 106:1 and 2.5 × 106: 1. It could be seen that the odds obtained by HLA testing were much higher, usually by two or more orders of magnitude than those of each of the other marker systems. This makes the HLA an excellent single test for the resolution of disputed parentage. The odds of the simultaneous occurrence of 2 children each assigned to the other family was calculated to be 1.7 × 101

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02969.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Lewis antisera produced in goats was used to test the red blood cells of 1,818 unrelated American adults and 758 unrelated children. All lived in northeastern states of the USA. Among 935 Caucasian adults, the frequency of Le(a‐b‐), Le(a+b‐), and Le(a‐b+), red cell phenotypes was 9.7, 20.1 and 70.2%, respectively. Among 883 Negro adults, the frequency of these phenotypes was 28.5, 19.6 and 51.9%, respectively. Among 469 infants aged 1–24 months, the red cell phenotype Le(a+b+) was found in 37.4% of 265 Caucasians and 13.2% of 20

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02970.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.A new low incidence blood group antigen ‘Mit’, immunization to which may cause hemolytic disease of the newborn, is described. It is not part of the ABO, Duffy, Kidd, Rh or Yt blood group systems. Positive lods of +2.41 at Θ = 0.00 indicate that the odds are 256 to 1 that ‘Mit’ is either part of the MNSs system or governed by a locus closely linked t

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02971.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.As a method of increasing supplies of varicella‐zoster immunoglobulin, semi‐automated screening of blood donors for high titre complement‐fixing antibody was initiated. This was compared with the previously used method of donor selection based on a history of varicella or zoster in the past 6 months. About one‐third of the ‘history’ donors had titres of?1 in 64 and generally these levels declined rapidly. In contrast, although only 1.1% of donors in random screening had antibody titres ? 1 in 64, these levels usually remained high during repeated donations, enabling the production of pools entirely composed of high titre p

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02972.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

摘要:

Abstract.Sera from 2,829 participants in a population health survey were tested for the presence of a heterophile antibody, detectable by immunofluorescence. The antibody was found in 9.8% of the sera from women and in 12.4% of the sera from men. The age‐specific prevalence of the antibody was relatively constant in women but rose steeply in men. The antibody occurred more frequently in individuals with a history of blood transfusion and in multiparous females. It is suggested that the antibody may result from immunization by a ubiquitous agent which can be transmitted by blood transfusio

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02973.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02974.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1980.tb02975.x

出版商:Blackwell Publishing Ltd    

年代:1980

数据来源: WILEY