摘要:

Abstract.More than 70 spontaneous chimeric propositi in man are known. This review attempts to summarize the information given by 32 twin chimeras, 32 dispermic chimeras and 11 chimeras of unestablished type.

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03657.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Abstract.α‐2‐L‐Fucosyltransferase activity was found in the sera of 4 H‐deficient secretor individuals (Hz). This activity represented about 5–10% of the activity present in the serum of normal H

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03658.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Abstract.Red blood cell (RBC) and platelet (PLT) transfusion requirements during the first 13 weeks after HLA‐identical marrow transplantation were studied in 82 patients with aplastic anemia. On the average, patients were given 9 units of RBCs (1–82) and 44 units of PLTS (6–468). The greatest need for support was during the first 4 weeks postgrafting. A multivariate statistical analysis of 22 variables showed that RBC and PLT requirements increased with age. In addition, RBC requirements increased if the patient had isohemagglutinins against the marrow donor's RBC, i.e., if the marrow transplant was across a major ABO ba

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03659.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Abstract.Red blood cells (RBC) stored without plasma in a neomycin, low ionic strength medium at 4°C in excess of 24 h show alterations in antigen reactivity. There is a loss of protease‐sensitive RBC antigens and a protease‐type increased IgG saline agglutinability of Rh antigens that is associated with increased binding of125I anti‐D. Both the serological findings and the alteration in RBC membrane polypeptides are consistent with protease modification of the membrane due to contamination of the RBC by leukocytes. Neomycin, low ionic strength or leukocytes alone or in dual combination do not produce the observed changes in antigen reactivity. The role of neomycin and low ionic strength in this phenomenon and implication for quality control of reagent RBC used for antibody detection and identification are dis

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03660.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

摘要:

Abstract.The occurrence of three major markers of hepatitis B viral (HBV) infection—the surface antigen (HbsAg), its specific antibody (HBsAb), and antibody to the core antigen (HBcAb)—is reported on 101 Kenyan volunteer blood donors which are tested by highly sensitive techniques.The surface antigen carrier rate was 14% by radioimmunoassay as opposed to 0.1–1% in Northern Europe and in the USA. The prevalence of the core aad surface antibodies is 53 and 57%, respectively. The core antibody as the only indicator of HBV infection occurred in 3% of Kenyan donors as compared to 0.4 in Caucasian volunteers. The overall infectious pool of HBV in Kenyan donors is 17%. Another application of the core and surface antibody screening of the blood donors has been reported recently in relation to the control of non‐A, non‐B posttransfusion hepatitis. The coexistence of the two antibodies is observed in 41% of the Kenyan donors after excluding the infectious pool. Exclusion of such a large proportion of donors to control non‐A, non‐B posttransfusion hepatitis is impractical in Kenya though it can be considered in Europe and in the USA where their prevalence rate is 1–4%. It is relevant to observe, however, that in spite of such high transmission rate of the virus in the community in Kenya, 25% of the adult population have been spared. As the immune status in relation to the HBV of the adult recipients of the blood is likely to be similar to that of the donors, a quarter are susceptible to the virus infection. The susceptible group is of course larger still amongst the paedia

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03661.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03662.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03663.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03664.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03665.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1983.tb03666.x

出版商:Blackwell Publishing Ltd    

年代:1983

数据来源: WILEY