ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01501.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The influence of red cell age on their agglutin‐obility by bloodgroup isoagglutinins was investigated in various ways. No definite differences between young and old red cells could be established although some experiments suggested a somewhat lesser agglutinability of the young cells in comparasion to the total cell populatio

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01502.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.New variants of the ABOH blood group system are described which are similar to the ‘Bombay’ phenotype, but differ from it by Le(a‐b+) erythrocytes and secretion of ABH and Leaand Lebantigens. The erythrocytes of the proposita and members of her family are group O, negative with anti‐H; agglutinins if the ‘Bombay’ type, active also at 37°C, but weakened owing to interference by the secreted antigens, were found in the sera. The genetic background of the observed phenotypes is discussed. It appears likely that the atypical blood groups are due to a pair of recessive genes at a locus designated as Z/z and responsible for biosynthesis of H antigen in erythrocytes. The Z/z locus very probably belongs to the operator/regulator gene complex for the structural geneH, and has a position similar that of theY/ypair in relation toAgene. The homozygous combination zz causes suppression (modification) of the H phenotype in erythrocytes. As a result, the expression of the blood groups, as determined by the structural geneAorB, is also suppressed. It is suggested that these variants (phenotypes) be given the symbols OHm, OAHm, OBHmand OABHmif the genetic information O, A, B or AB can be demonstrated only indirectly, and symbols AHmand BHmif the phenotype can be demonstrated by specific agglutinati

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01503.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A study of 146 antenatal patients having anti‐E strongly suggests that most anti‐E's, particularly those of the papain reactive type, are initially due to a ‘natural’ stimulus, and are further stimulated by pregnancy and tran

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01504.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.A good anti‐H was found inCerastium tomentosumseeds. It was studied and compared with other seed anti‐H agglutinins. A spectrum of activity appears to exist which ranges from thel‐fucose specific agglutinin ofLotus tetragonolobusto those agglutinins which react more strongly with normal than with Ohcells. The reactions of theLotusagglutinin provided further evidence of a close steric association between the ABH and Ii rece

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01505.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.The absorption of blood group A‐decomposing enzyme fromClostridium tertiumon the red cell surface was examined. The enzyme was thoroughly absorbed on the surface of red cells of blood group A. Cells which were treated for a few minutes and separated from the enzyme solution lost their A‐activity more rapidly than those which were maintained in enzyme solution. Enzyme absorption occurs with biochemical and biophysical specificity; i.e. A‐enzyme is absorbed solely on A‐cells and it competes with anti‐A agglutinin fromEuphadra periomphalafor their reactive sites. N‐acetyl‐D‐galactosamine and D‐galactosamine are considered to release cell‐fixed A‐enzyme

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01506.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.Material with high Sdablood group activity can be prepared from urine by precipitation with ethanol. Partial separation of substances with Sdaand A activity can be effected by gel‐filtration, ultracentrifugation or precipitation with anti‐A serum. Substances with Sdaactivity are inactivated by acid, alkali and periodate and are partly soluble in phe

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01507.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

摘要:

Abstract.30 D‐negative subjects immunised by pregnancy or transfusion all had anti‐D concentrations of less than 4 μg/ml. Following re‐stimulation with D‐positive cells 14 of the 30 achieved anti‐D concentrations of over 40 μg/ml. The rise in antibody concentration was accompanied by a small rise in the average equilibri

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01508.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01509.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY

ISSN:0042-9007    

DOI:10.1111/j.1423-0410.1970.tb01510.x

出版商:Blackwell Publishing Ltd    

年代:1970

数据来源: WILEY