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1. |
Atrial Natriuretic Factor in Patients with Liver Disease |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 89-100
Murray Epstein,
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ISSN:0250-8095
DOI:10.1159/000167944
出版商:S. Karger AG
年代:1989
数据来源: Karger
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2. |
Fatal Hepatic Necrosis Caused by Disseminated Type 5 Adenovirus Infection in a Renal Transplant Recipient |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 101-105
Stephen H. Norris,
Thomas C. Butler,
Neal Glass,
Rue Tran,
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摘要:
This is an unusual case of fatal hepatic necrosis caused by disseminated type 5 adenovirus in a renal transplant recipient. This adult patient may have been colonized at the time of transplantation with a kidney from a pediatric donor. The adenovirus became invasive when the host’s cellular immune system was suppressed by high doses of corticosteroids given to reverse acute allograft rejectio
ISSN:0250-8095
DOI:10.1159/000167945
出版商:S. Karger AG
年代:1989
数据来源: Karger
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3. |
Acute Renal Failure due to Mannitol Intoxication |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 106-109
Kevin J. Horgan,
Y.L. Ottaviano,
Alan J. Watson,
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摘要:
A case of mannitol-induced renal failure is described and previously reported cases are reviewed. Possible mechanisms of the etiology are discussed.
ISSN:0250-8095
DOI:10.1159/000167946
出版商:S. Karger AG
年代:1989
数据来源: Karger
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4. |
Announcement |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 109-109
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PDF (98KB)
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ISSN:0250-8095
DOI:10.1159/000167947
出版商:S. Karger AG
年代:1989
数据来源: Karger
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5. |
Apolipoprotein B Immunochemical Heterogeneity in Dialysed Patients with Chronic Renal Failure and Patients with Coronary Artery Stenosis |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 110-114
Richard Reade,
Venance Equagoo,
Claude Cachera,
Patrick Duriez,
Michel Dracon,
Jean-Marie Bard,
Catherine Fievet,
Michel Bertrand,
Albert Tacquet,
Jean-Charles Fruchart,
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PDF (1021KB)
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摘要:
Serum cholesterol, triglyceride, apolipoprotein B (apo B) and the cholesterol and phospholipid content of apo-B-containing particles was determined in 41 male patients on dialysis for chronic renal failure, in 41 male patients with coronary artery disease selected on the basis of a total cholesterol level below 6.72 mmol/l and in 41 male control subjects of similar age. Apo B was assessed as total B protein determined using polyclonal antibodies and also by measuring the expression of epitopes recognized by three different monoclonal antibodies (BL3, BL5 and BL7). Triglyceride was increased (p < 0.01) and cholesterol was decreased (p < 0.01) in the dialysed patients with chronic renal failure. Total apo B was similar in the three tested groups while the expression of the BL7 epitope was increased in the group of dialysed patients with chronic renal failure (p < 0.001). The expression of BL3 and BL5 epitopes was increased in patients with coronary artery disease (BL3: p < 0.05; BL5: p < 0.02) but not in dialysed patients with chronic renal failure. These results suggest an abnormal composition and an immunological heterogeneity of apo-B-containing lipoprotein particles in patients with coronary artery stenosis and in dialysed patients with chronic renal failure.
ISSN:0250-8095
DOI:10.1159/000167948
出版商:S. Karger AG
年代:1989
数据来源: Karger
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6. |
Dialysis for Chronic Renal Failure: Comorbidity and Treatment Differences by Disease Etiology |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 115-123
Stephen E. Radecki,
Allen R. Nissenson,
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PDF (1749KB)
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摘要:
A national sample of dialysis physicians was used to obtain data for a comparison of patient characteristics, comorbid conditions and treatment patterns associated with the five leading causes of end-stage renal disease (ESRD). The data are used to assess trends in physician care for ESRD patients and likely changes in program costs. The analysis shows that patients with glomerulonephritis are the youngest. Those with hypertensive nephropathy are the oldest, and include the highest proportion of blacks, while those with polycystic kidney disease include the lowest proportion of blacks. Patients with diabetic nephropathy have the most problems noted at the time of physician contact, the most emergent and severe problems, the highest number of diagnostic tests utilized, the most complex treatments required and the longest physician time spent per encounter. Patients with ‘other interstitial nephritis’ are significantly more likely to have infections, musculoskeletal disorders, chronic obstructive pulmonary disease and neoplasms noted as comorbid conditions. They also have the highest number of therapeutic procedures and the greatest percentage of referrals for consultations. Survey data highlight the evolving nature of Medicare’s ESRD program. With increasing numbers of elderly and diabetic patients, more physician time will be required for the overall care of the dialysis patient, and increasing costs associated with necessary diagnostic tests and referrals can be exp
ISSN:0250-8095
DOI:10.1159/000167949
出版商:S. Karger AG
年代:1989
数据来源: Karger
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7. |
Clinical Follow-Up of 54 Patients with IgM-Nephropathy |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 124-128
Heikki Saha,
Jukka Mustonen,
Amos Pasternack,
Heikki Helin,
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摘要:
The clinical course of mesangial glomerulopathy with IgM deposits (IgM-nephropathy) was studied in 54 patients. The initial manifestations of the disease were nephrotic syndrome in 18, proteinuria in 21, proteinuria together with hematuria in 4 and isolated hematuria in 11 patients. The nephrotic syndrome was steroid-responsive in 60% of cases and of these 80% were steroid-dependent. During a 5-year postbiopsy follow-up 3 patients went into terminal uremia and in 6 more patients a milder renal insufficiency was observed. Three patients were rebiopsied and in 2 of these the second biopsy specimen disclosed typical focal and segmental glomerulosclerosis. Hematuria was a favorable sign, as no patient with hematuria showed progressive impairment of renal function. The prevalence of hypertension in the whole material was 37%. At close of follow-up 35% of all patients were in clinical remission. It is suggested that IgM-nephropathy associated with abundant proteinuria or the nephrotic syndrome represents a distinct disorder from that associated with hematuria. While the nephrotic type often manifested itself with a morphologic change and a tendency to develop renal insufficiency, the hematuric type showed female predominance, a high tendency to spontaneous clinical remission and a favorable clinical course.
ISSN:0250-8095
DOI:10.1159/000167950
出版商:S. Karger AG
年代:1989
数据来源: Karger
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8. |
Acute Non-Dilating Obstructive Renal Failure in a Patient with AIDS |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 129-132
David A. Spector,
Robert S. Katz,
Harold Fuller,
Lynda M. Cristiano,
Susan Vitalis,
John Jarrow,
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摘要:
A 30-year-old male who presented with acute renal failure was found to have acquired immunodeficiency syndrome (AIDS). Although sonography and computerized tomography did not show urinary tract dilatation, obstructive renal failure was demonstrated by retrograde pyelography. Relief of obstruction(s) due to encasement of the renal pelves and ureters with histiocytic lymphoma led to immediate return of normal renal function. Although the etiology of renal failure in this patient is highly unusual, the high incidence of lymphoma in patients with AIDS should make tumor-related renal disease a consideration in all such patients with renal dysfunction.
ISSN:0250-8095
DOI:10.1159/000167951
出版商:S. Karger AG
年代:1989
数据来源: Karger
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9. |
Relationship between Plasma ANF Responsiveness and Renal Sodium Handling in Cirrhotic Humans |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 133-143
Murray Epstein,
Rodger Loutzenhiser,
Peter Norsk,
Steven Atlas,
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摘要:
The responsiveness of atrial natriuretic factor (ANF) to central volume expansion and its role as a determinant of the natriuretic and diuretic responses of cirrhotic patients was evaluated utilizing water immersion (WI). Following equilibration on a 10-mEq sodium diet, 9 seated cirrhotic patients were studied during 3 h of WI. Before WI, plasma ANF levels (10.9 ± 2.4 fmol/ml) were similar to those previously observed in normal sodium-replete subjects (7.7 ± 0.9 fmol/ml). Five of the 9 cirrhotic subjects manifested an exaggerated peak ANF response, whereas the remaining 4 manifested increases similar to those of normals. The concomitant natriuretic response varied widely, ranging from absent to markedly exaggerated responses. The peak urinary sodium excretion varied independently of peak plasma levels of ANF and peak change of ANF from the prestudy hour (r = 0.36, p > 0.20, and r = 0.46, p > 0.20, respectively). Thus, in contrast to normal subjects, in whom the immersion-induced natriuresis correlated closely with the changes in ANF, the natriuretic responses of cirrhotic patients were dissociated from the concomitant increases in ANF. These observations indicate that sodium retention in cirrhosis is not attributable to impaired ANF releas
ISSN:0250-8095
DOI:10.1159/000167952
出版商:S. Karger AG
年代:1989
数据来源: Karger
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10. |
Quiz of the Month, Questions |
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American Journal of Nephrology,
Volume 9,
Issue 2,
1989,
Page 144-144
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PDF (189KB)
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ISSN:0250-8095
DOI:10.1159/000167953
出版商:S. Karger AG
年代:1989
数据来源: Karger
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