ISSN:0250-8095    

DOI:10.1159/000166737

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

The effect of renal transplantation on acquired cystic disease of the kidney in patients who have been on hemodialysis for more than 5 years was examined in 7 cases by computer-assisted tomography (CT scan). Almost all acquired cysts disappeared, and the size of the original kidneys decreased remarkably in 2 cases 8–10 months after transplantation. 3 other patients, in whom CT scans were performed only after transplantation, showed contracted scarred kidneys with few or no cysts. The involution of acquired cysts was incomplete in 1 case, in whom the cysts persisted for 3 years and 2 months, despite normal renal function. The last case, who was off hemodialysis only for 4 months, exhibited enlargement of the original kidneys and an increase in the number of cysts. These results suggest that a significant number of acquired renal cysts in dialyzed patients with end-stage kidney disease regress rapidly after successful renal transplantation, but this is not always s

ISSN:0250-8095    

DOI:10.1159/000166738

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

A study on the specificity of antibodies eluted from renal biopsy specimens from patients with Henoch-Schönlein purpura (HSP) nephritis, IgA nephropathy and other glomerular diseases is described. The specimens were treated with citrate buffer, pH 3.2, and the ‘eluate’ was neutralized by sodium hydroxide. The ‘eluate’ was then applied to the acid-treated sections obtained from the same patients and from other patients with HSP nephritis as well as to the sections from patients with IgA nephropathy and other glomerular diseases. The ‘sections were stained with FITC-labeled heavy-chain specific anti-human IgA antisera and then examined with a fluorescent microscope. It was demonstrated that the antibodies obtained from patients with HSP nephritis specifically recombined with the glomerular mesangial areas in patients with IgA nephropathy and vice versa, whereas they did not combine with renal tissues obtained from patients without IgA nephropathy. These antibodies did not show antimesangial activity since they did not react with normal glomeruli or nephritic glomeruli other than those from cases with HSP nephritis and/or IgA nephropathy. The specificity of IgA antibodies was confirmed by various tests using anti-human IgA antisera, human IgA myeloma protein, whole serum samples, human γ-globulin absorbed with anti-human IgG and/or IgM antisera or clostral IgA. It is suggested that some common antigens may be involved in the development of HSP nephritis and IgA

ISSN:0250-8095    

DOI:10.1159/000166739

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

Pericarditis with or without effusion as a complication of end-stage renal disease responds to the institution of chronic dialytic therapy. The management of pericardial effusion which has its onset after some time of chronic dialytic therapy is less well established. Since a surgical pericardial drainage procedure is often performed on an emergency basis in some patients with pericardial effusion treated with maintenance dialysis, it would be advantageous to be able to predict which patients would subsequently require an operation which then could be performed electively. Thus, we reviewed our experience with pericardial effusion in patients treated with maintenance dialysis in order to ascertain whether one or more factors would predict the ultimate need for a surgical pericardial drainage procedure. Our analysis of 22 patients with pericardial effusion demonstrates that those with a large effusion are best treated by elective pericardial drainage using a subxiphoid approach with instillation of triamcinolone hexacetonide into the pericardial sac. Those patients with a small or moderate effusion can be subjected to a trial of nonsteroid anti-inflammatory drugs and/or intensive dialysis. Evidence of an enlarging effusion should prompt surgical drainage before hypotension or tamponade require the patient to undergo an emergency operation.

ISSN:0250-8095    

DOI:10.1159/000166740

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0250-8095    

DOI:10.1159/000166741

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0250-8095    

DOI:10.1159/000166742

出版商:S. Karger AG    

年代:1983

数据来源: Karger

摘要:

A patient with a single kidney and oliguric renal failure for 47 days experienced dramatic restoration of glomerular filtration and renal function following graft bypass of an occluded renal artery. There was very little evidence of acute tubular necrosis. The case emphasizes the importance of the renal collateral circulation in the maintenance of tissue viability, even when the hydrostatic pressure of collateral flow is inadequate for glomerular ultrafiltrate formation. The differentiation of oliguric renal failure due to renal arterial occlusion from that due to acute tubular necrosis following arterial injection of radiocontrast material is imperative because of the dramatic response to reconstructive vascular surgery.

ISSN:0250-8095    

DOI:10.1159/000166743

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0250-8095    

DOI:10.1159/000166744

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0250-8095    

DOI:10.1159/000166745

出版商:S. Karger AG    

年代:1983

数据来源: Karger

ISSN:0250-8095    

DOI:10.1159/000166746

出版商:S. Karger AG    

年代:1983

数据来源: Karger