摘要:

AbstractFive‐day‐old mouse blastocysts were transferred into the oviducts of recipients on the second day of pregnancy. S35methionine was then injected into the recipients and the blastocysts and native 2‐celled eggs were recovered six hours later. Radioautographs reveal that the blastocysts incorporate S35methionine while exposed to the tubal environment to the same degree that they would in the uterus. However, the 2‐celled eggs in the same oviducal environment incorporate little or no methionine. It is therefore concluded that the difference in the incorporation of S35methionine is due to maturational changes in the blastocyst rather than to a deficiency of the labelled amino acid in the tuba

ISSN:0003-276X    

DOI:10.1002/ar.1091590302

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractMicroradiographs of 100‐300 μ slices of dog lungs which had pulmonary veins injected with barium sulphate showed good filling of brochial veins. Bronchial veins joined pulmonary veins at frequent intervals along the longitudinal axis and around the circumference of bronchi. Frequently, pulmonary veins and pulmonary capillaries entered the bronchial venous system, suggesting venous flow from lung to bronchus. Single veins along the margin of small bronchi (1 mm) received both pulmonary venous and bronchial venous blood. Therefore, there was a particularly intimate relationship between pulmonary and bronchial veins. The submucous venous plexus was prominent and was composed of thin‐walled, 50 μ‐diameter veins which had surprisingly direct connections to pulmonary veins. The proximity of a large venous plexus to the airway lumen suggested that oxygen transport could occur, thereby reducing venous admixture of the arteria

ISSN:0003-276X    

DOI:10.1002/ar.1091590303

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractLongitudinal series of hand x‐rays from healthy white children (116 boys, 118 girls) of Fels growth studies were investigated. Notchings of the nonepiphyseal end of the first, second and fifth metacarpal bones were found in every child. Beginning from infancy or early childhood, the notchings follow a sequence of developmental stages (obtuse‐angle; acute‐angle; cleft: underlying, edge‐to‐edge, overjutting; and fusion) until they disappear one to one and one‐half years before onset of puberty. The notching intensity in the second and the fifth metacarpal bones was rated. A moderate degree of association in notching intensity was demonstrated between brothers

ISSN:0003-276X    

DOI:10.1002/ar.1091590304

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractThe activity of alkaline phosphatase, acid phosphatase, glutamic‐oxalacetic transaminase (GOT), lactic dehydrogenase (LDH), amylase, succinic dehydrogenase (SDH), glucose‐6‐phosphate dehydrogenase (GD) has been determined in the rabbit endometrium at estrus, in pseudopregnancy, and at days 5–10 of pregnancy. Enzyme analyses were also made on the placenta and embryo during early pregnancy.The most striking changes were increases in the SDH and GDH levels of the endometrium and a decrease in amylase when the does became pregnant or pseudopregnant. Amylase did not rise significantly from its lower level between five and ten days of pregnancy; SDH and GDH activity, however, fell away after reaching a maximum prior to implantation. At implantation there was some evidence of an increase in LDH and phosphatase activity. All enzymes had lower activities following implantation (10 days pregnancy). The endometrial enzyme activities of prepubertal does were usually similar to those of adult females in estrus. However, alkaline phosphatase activity of the prepubertal endometrium was particularly low.The activity of enzymes in the placental areas were, in general, similar to those found in the interplacental areas of the endometrium. However, from 7–10 days of pregnancy the activity of SDH was lower in the placental area than in the interplacental areas; whereas, amylase was higher on the eighth and ninth days of pregnancy. Changes in the activities of the phosphatases, GOT and SDH occurred in the blastocyst and trophoblast on eight to ten days of pregnancy. Enzyme activities in blastocoelic fluid were much less than in the trophoblast with the exception of amylase which w

ISSN:0003-276X    

DOI:10.1002/ar.1091590305

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractSystematic experiments have resulted in a method of decalcification which, although specifically developed for cytological study of reptilian aural tissue, should be applicable to other problems involving electron microscopy of organic components of bone or tissues closely associated with bone. Reptilian otic capsules and control specimens of mammalian hepatic tissue were subjected to planned variations of fixatives and decalcifying agents, embedded, sectioned, and evaluated by light and electron microscopy. Additionally, applicability of the more satisfactory agents to other mammalian tissue was checked by limited testing on specimens from Mongolian gerbils. Acceptable results were achieved in tissues fixed in glutaraldehyde, and then decalcified in cold 0.1 M solutions of disodium or tetrasodium EDTA (adjusted to pH 7.2–7.4 with sodium hydroxide or versenic acid, respectively), containing 4.0% glutaraldehyde; following decalcification, specimens were washed in buffer, postfixed in osmium tetroxide, and embedded in epoxy resins with minor modification of standard techniques. Acceptable cytological detail and morphological relationships were retained, and extended treatment with the decalcifying solution did not apparently result in degradation of tissue

ISSN:0003-276X    

DOI:10.1002/ar.1091590306

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

Abstract“Brown degeneration,” a pigmentary process of the adrenal gland of the mouse, was consistently induced by administration of ethinyl estradiol. Mice similarly treated with diethylstilbestrol or peanut oil (control) developed only small amounts of pigment. Histochemically, the pigment was ceroid and had its origin in the inner cells of the cortex in both females and males, with the fully developed pigmentation distributed in the cortex in animals of both sexes, and also in the medulla in males. Ultrastructurally, ceroid formation progressed from small pigment granules morphologically similar to lysosomes, to large composite, pleomorphic pigment bodies composed of unique granular configurations and membranous components. The ceroid deposits were interpreted to represent lipid products resulting from altered fat metabol

ISSN:0003-276X    

DOI:10.1002/ar.1091590307

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractThis report describes lesions observed in excurrent ducts of the testis in 152 of 518 rats, in the course of studies concerned with cadmium‐induced testis injury and the actions of selenium and zinc, separately and combined, in protecting against such damage. All elements were injected subcutaneously, as soluble salts. Necropsy was usually five days (77% of rats) after cadmium injection, but lesions were observed within six hours.Ductuli efferentes showed variable degrees of sperm blockage, epithelial hyperplasia and metaplasia, periductal round cell infiltration, fibrosis and contraction. In 56 of 93 rats showing only ductuli lesions, testes were either normal or exhibited dilation of the rete testis and of variable numbers of seminiferous tubules, with or without “pressure degeneration” of the germinal epithelium. In the other 37 rats, the testes showed cadmium‐induced injury.Lesions involving both ductuli efferentes and proximal segments of the caput epididymis (13 rats), or the latter alone (46 rats), tended to be associated with more severe testis damage. Epididymal lesions were characterized by focal proliferation and desquamation of duct epithelia, and formation of spermatoceles.The lesions observed were attributed primarily to ischemia, secondary to effects of cadmium upon the capillary bed of the tissues involved. However, their possible enhancement or modification by direct chemical action of cadmium, selenium or zinc upon the duct system or perivascular tissues could not be e

ISSN:0003-276X    

DOI:10.1002/ar.1091590308

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

摘要:

AbstractThe time of intrauterine migration and spacing of embryos was determined in 36 gilts with one oviduct occluded, and in 48 gilts with one ovary. Embryos could enter the uterus from one oviduct only. Uteri of seven pregnant gilts were examined on each of days 6, 7, 8, 9, 10, 11, 12, 13, and 15 of gestation. Migration of embryos from one horn to the other usually occurred first on day 8 or 9. The uterus was occupied completely by day 15. Rate of migration and distribution of embryos was not affected by number of embryos, number of corpora lutea, or by uterine length. Uterine length did not change between days 6 and 15. Bilateral ovariectomy after breeding was associated with arrested growth of embryos, a decreased rate of embryo migration and a reduction in uterine length.

ISSN:0003-276X    

DOI:10.1002/ar.1091590309

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

ISSN:0003-276X    

DOI:10.1002/ar.1091590310

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY

ISSN:0003-276X    

DOI:10.1002/ar.1091590301

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1967

数据来源: WILEY