摘要:

AbstractA gland lying in the lateral wall of the nasal cavity of the rat has been described and identified as the “lateral nasal gland.” The gland cups the outer aspect of the alveolar bone of the upper incisor root, and lies between it anteriorly, and the alveolar bone of the root of the first molar posteriorly. It is bounded by the hard palate ventrally, the infraorbital fissure laterally and the nasal mucosa, medially and dorsally. The gland consists of serous acini, the secretion granules of which are rich in PA‐Schiff positive material. These acini are clearly distinguished from the mucous‐secreting nasal mucosal glands which lie in the mucosa and border the acini of the lateral nasal gland. The acini of the lateral nasal gland are drained by intercalated ducts into striated ducts which anastomose to form the principal excretory duct. The latter pursues a long tortuous course beneath the mucosa of the lateral nasal wall to open into the nasal vestibule near the externa

ISSN:0003-276X    

DOI:10.1002/ar.1091470402

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractThe anatomy of reproductive organs including histology and cytology of the gonads of one‐year‐old bovine quintuplets were investigated. The experimental animals were four freemartins and one fertile bull with normal sexual libido. In all four freemartins the cervix was absent but the vestibule and the uterine horns were present. The highest degree of transformation of an ovary toward the male pattern was characterized by absence of germinal epithelium, secondary tunica albuginea, ovarian cortex, and follicles; and by presence of mesothelium, primary tunica, tunica vasculosa, interstitial cells, primary sex cords, centrally located rete, epididymis and ductus deferens.Least transformation was characterized by partial presence of ovarian cortex with germinal epithelium, secondary tunica and primordial, growing and Graafian follicles with oocytes and nuclei in prophase of heterotypic division and more peripherally located rete. Histological transformation of gonads was parallel to anatomical transformation of reproductive organs. One male embryo was able to masculinize four of the female quintuplets at a lesser degree than that generally reported in the literature for twins and triplets. The histological differences of the right and left gonad of the same freemartin may be due to differences in the stage of embryonic development or, the sensitivity of the gonadal tissues at the time threshold amounts of circulating substances of male origin were available. The presence of oocytes in the luteal structures may indicate that the lutein cells of such structures originate from luteinized unruptured follicles rather than from the interstitial ce

ISSN:0003-276X    

DOI:10.1002/ar.1091470403

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractNew Zealand virgin rabbits were used in this study. Normal males and castrated, thyroidectomized and recently mated females formed the control groups. Correlation with the light microscopical appearance using the method of alternate thin and thick sections, correlation with the control glands, and comparison with the descriptions in the rat, were used as criteria for the identification of five different types of secretory cells in the pars distalis. Two types of “acidophiles” were found, the more numerous and conspicuous having secretory granules of a maximum diameter of 380–400 mm̈ (growth hormone‐producing cell), and a second type with granules of 600–800 mm̈, very seldom seen in the virgin rabbit but increasing in number and granulation after mating (Prolactin‐producing cell). Two types of “basophiles” that correspond to the “thyrotrophes” (angular shape, granules of 150 mm̈ in diameter) and “gonadotrophes” (rounded shape, granules of 280–300 mμ), were also identified. In addition, a peculiar large cell with characteristic mottled cytoplasm and very few granules was tentatively identified as a “basophile” in the process of regranulation. Its functional significance was discussed. A stellate cell having fibrillar material and no secretory granules within its cytoplasmic processes, found between parenchymal cells and approaching basement membranes, was tentatively identified as a supporting element. In addition to the description of the fine structure and possible functional significance of the different cell types, some features as cilia, desmosomes, intranuclear fibrillar material, as well as vacuolization of cells in

ISSN:0003-276X    

DOI:10.1002/ar.1091470404

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractThe ground squirrel,Citellus tridecemlineatus tridecemlineatus, is a strictly diurnal species and possesses a pure‐cone retina. The present work comprises the results of an investigation of the morphology and the histological structure of the lateral geniculate body of this interesting mammal. The lateral geniculate body of the nocturnal guinea pig was also investigated and a comparison of the two made.In both species, the lateral geniculate body comprises two nuclei: a smaller ventral and a larger dorsal. These nuclei are devoid of lamination — a feature presumably related to the absence of binocular vision in these animals. Only the dorsal nucleus projects to the cortex in both species.Measurements on 1,000 neurons in the dorsal nucleus of both species reveal that neuron population is uniform in size and that on the average the neurons of the guinea pig are a little smaller (ground squirrel, nucleus: 12.36 m̈; perikaryon: 16.70 m̈ and guinea pig, nucleus: 12 m̈; perikaryon: 15.82 m̈).The lateral geniculate body of the guinea pig is smaller than that of the ground squirrel. The dorsal nucleus in the latter species is estimated to contain 74,900 neurons. This is a large number and undoubtedly is related to the fact that the retina is pure‐cone with numerous ganglion cells and a large op

ISSN:0003-276X    

DOI:10.1002/ar.1091470405

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractPregnant Wistar rats were injected subcutaneously with trypan blue and the heart was studied in 206 embryos removed at daily intervals from ten and one‐half to fourteen and one‐half days of gestation.Cardiac anomalies appeared to be largely due either to malpositioning of the atria consequent upon an abnormal looping of the bulbo‐ventricular loop, or to a decreased formation of cardiac jelly.The hearts of a further 46 embryos at ten and one‐half days were studied histochemically and 40 of these (24 experimental and 16 control) were stained with Best's carmine. Glycogen granules were found in the hearts of experimental embryos but not in the hearts of control embryos.It is suggested that trypan blue may act directly on the cells of the myoepicardium of the developing rat heart, causing a precocious transition to the biochemical characteristics of the adult tissue with a consequent decrease in the amount of cardiac jelly formed. The abnormal looping of the bulbo‐ventricular part of the cardiac tube might also be consequent upon such a biochemic

ISSN:0003-276X    

DOI:10.1002/ar.1091470406

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractExplants of human synovialis obtained surgically were cultivated under dialysis membrane in the multipurpose Rose chamber and in Eagle's medium enriched with 20% pooled human cord sera. Within 24 hours monocytes and lymphocytic cells emerged from the majority of explants while spindle and stellate cells appeared later on the second and third days of culture. A monolayer of cells developed in which active mitosis was observed. Between 12 to 15 days, fingerlike projections of cells adjacent to the explants branched out between the cover glass and the monolayer of mesenchymelike growth and by the twenty‐fifth day had developed into anastomosing networks eventually ranging in length from 1.2 to 3.2 mm. Ciné and still phase photomicrographs decumented findings. Vascular networks developedin vitroin 85% of the total 80 Rose chambers examined over an average period of 58 days. Minute vessels, patent for only short distances, were lined with endothelial cells characterized by slender elongated nuclei and with two or three small nucleoli. In contrast, flanking fibroblasts were considerably larger with clear oval nuclei containing conspicuous nucleoli. Differential stains demonstrated reticular fibers and distinct bundles of collagen lying along the vessels, particularly in the area adjacent to the fragment. In the study of rheumatoid arthritis, where vascular lesions are known to occur, it is possible that such preparations may provide favorable test objec

ISSN:0003-276X    

DOI:10.1002/ar.1091470407

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

摘要:

AbstractVascularization of subcutaneous (ear) and mesenteric adrenal autografts, homografts, and x‐irradiated autografts was studied microscopically through visualization of small blood vessels by intravascular precipitation of lead chromate. Vascularization of autografts in both sites begins on the third day after transplantation with a surface network of small vessels. Vascular buds penetrate the graft on the fourth day. On the seventh vascularization is complete. Vessels penetrate along regenerated adrenocortical fasciculi. Later, large vessels supplying the network around the graft are prominent and venous sinuses exist near the surface. Vascularization of subcutaneous homotransplants follows the same qualitative course but is chronologically irregular, delayed one or more days in most cases. On the second day an inflammatory vascular reaction occurs around the wound in the ear. Generally, vessels are finer, less well injected than in autografts. Mesenteric homografts, however, are vascularized like mesenteric autografts. X‐irradiation of adrenalsin vitrowith 2,000 r prior to autografting also produces chronological irregularity and retardation of vascularization, up to 28 days after subcutaneous transplantation, but only during the first 12 days in mesenteric transplants. Except for reduction in size, from the thirteenth day on, x‐irradiated mesenteric transplants are like non‐irradiated c

ISSN:0003-276X    

DOI:10.1002/ar.1091470408

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

ISSN:0003-276X    

DOI:10.1002/ar.1091470409

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY

ISSN:0003-276X    

DOI:10.1002/ar.1091470401

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1963

数据来源: WILEY