摘要:

AbstractUtilization of peroxidase‐labeled antibody to porcine corticotropin permitted the delineation of a distinctive cell in the hypophyseal pars distalis of the rat that appears to be the source of corticotropin. Corticotropin cells were stellate and possessed processes that ended on the walls of sinusoids. Corticotropin cells composed a small percentage of the total cell population, and were distributed throughout the gland except that they were less common posteriorly, superiorly, and immediately alongside the pars intermedia. Alteration in size of corticotropin cells was related directly to change in corticotropin content of the gland as effected by differing physiological conditions. Thus, they were larger in the female than in the male and were enlarged after adrenalectomy of the male; they became much smaller following treatment of the female with cortisol. Some corticotropin cells stained with aldehyde fuchsin and the periodic acid‐Schiff (PAS) reaction. These reactions were more intense if hormone antibody and the gamma‐globulin conjugate had been applied previously. However, the capacity of some corticotropin cells to stain weakly with PAS without prior application of antibody suggests that they may contain mucopr

ISSN:0003-276X    

DOI:10.1002/ar.1091660402

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractA surface planimeter was used to assess tetracycline‐labelled areas of undecalcified sections of the maxillas of 16 male guinea pigs. In three different molar regions studied, highest values were found in the last‐molar region, followed by the first‐molar and second‐molar region. In the 32–42 day old animals the values in the incisal region were higher than in the first‐and‐second‐molar region, but lower than in the last‐molar region. In the age groups of 47–57 and 62–67 days, proportions of labelled bone in the incisal regions were lower than those found in the first‐molar and last‐molar regions, but approached the level of those found in the second‐molar region. There were statistically significant age‐associated differences and varying amounts of lab

ISSN:0003-276X    

DOI:10.1002/ar.1091660403

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractThe electron microscopic observations of liver cells from normal, fasted, diabetic, and insulin‐treated diabetic rats were compared. The most striking electron microscopic features were the sparsity of glycogen particles in fasted and diabetic rat liver cells and the diminution in lamellar formations of rough endoplasmic reticulum in the diabetic animals. Forty‐one hours of insulin treatment of diabetic rats restored the appearance of liver cell structure to normal. These variations in liver cell fine structure were correlated with circulating insulin levels and previously reported enzyme activit

ISSN:0003-276X    

DOI:10.1002/ar.1091660404

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractFetal‐maternal interfaces of rat placentas, obtained from midgestation to term, were examined for their content of electron‐dense fibrinoid. Although increased amounts of interfacial fibrinoid were noted as the time of parturition was approached, at no time did fibrinoid form an intact, electron‐dense barrier between the fetal trophoblast giant cells and the maternal decidual cells of the definitive rat placenta. Large areas of apparently viable fetal trophoblast and viable maternal decidua were intimately juxtaposed throughout the latter half of pregnancy. It is concluded that a poorly discontinuous layer of fibrinoid cannot serve as an effective barrier to a proposed flow of transplantation antigens from the fetoplacental unit to the maternal

ISSN:0003-276X    

DOI:10.1002/ar.1091660405

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractEndothelial fenestrations have been observed in the venules of the large salivary glands of mice. The structure of the fenestrations is similar to those of capillaries. The fenestrations are frequently demonstrated in the endothelium of the transitional portions from a capillary to a venule. They are also seen in overlapping thin cytoplasm located on either the blood or tissue front of the endothelial cells of the venules at cell junctions.

ISSN:0003-276X    

DOI:10.1002/ar.1091660406

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractReconstruction of the pulmonary and aortic trunks, together with adjacent structures in a 41 mm human embryo of the Carnegie Collection, demonstrates that as late as the ninth week after ovulation the bronchial artery is still a tiny vessel, arising ventrolaterally from the descending aorta at the level of the third pair of dorsal aortic‐intercostal arteries, and that any extension of it along the bronchial tree must still be of capillary calibre since no visible branches can be followed into the root of the lung. In sum, bronchial arteries arise later, more slowly and from a lower position than has hitherto been assumed. By contrast, the anomalous systemic pulmonary artery that supplies the right posterior basal bronchopulmonary segment in this fetus and which now arises from the aorta just above the celiac artery, is a robust vessel. Such systemic pulmonary arteries must arise very early, at the level of the definitive pulmonary arteries, and keep pace with them in growth, whether or not their stems descend along the aorta with the migrating celiac arter

ISSN:0003-276X    

DOI:10.1002/ar.1091660407

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractHistochemical characteristics of the integumentary mucous glands of the leopard frog (Rana pipiens) are described so that their role in water balance can be better understood. Mucus is acidic, due to its content of sulfate and carboxylic acids. The carbohydrate moiety contains periodate‐engendered groups which are not in close proximity to acid radicals. Protein was not demonstrated. Neuraminic acid is either absent or is not susceptible to neuraminidase digestio

ISSN:0003-276X    

DOI:10.1002/ar.1091660408

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractA C‐shaped bar of hyalin cartilage was present in the fibrous tissue around the aortic orifice in the heart of all 70 male and 10 female Syrian hamsters, 103 to 843 days old. This cartilage has the same cellular and intercellular characteristics as the tracheal cartilages. Fibers from four of the six lunulae of the semilunar aortic valves, the aortic sinuses and vestibule, and cardiac muscle adjacent to the posterior semilunar valve insert onto the fibrous capsule and the protuberances of the aortic cartilage. A few fibers from the ventricular and interatrial septa and the aortic cusp of the mitral valves are also attached to the fibrous capsule. Cartilage did not occur around the pulmonary orifice or in other regions of the heart with the exception of a chondroma in the aortic valve. The C‐shaped aortic cartilage in this hibernating species is discussed in relation to its possible significance in preventing collapse of the aortic orifice and the possibility of increasing coronary blood f

ISSN:0003-276X    

DOI:10.1002/ar.1091660409

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractThe formation of peribiliary dense bodies in developing rat liver was studied by electron microscopy. Dense bodies arise in close conjunction with an extensive Golgi apparatus which displays acid phosphatase, inosine diphosphatase and thiamine pyrophosphatase activity throughout development. The position of these enzymes within the Golgi apparatus appears somewhat variable. Dense bodies are present by the thirteenth day of development and gradually increase in number. They show acid phosphatase activity from their earliest appearance. These findings demonstrate that: (1) peribiliary dense bodies are lysosomal from their earliest appearance; (2) they apparently arise directly from a well‐developed Golgi apparatus; and (3) the Golgi apparatus contains several enzymes simultaneously, suggesting that it becomes multifunctional at an early stage of developmen

ISSN:0003-276X    

DOI:10.1002/ar.1091660410

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY

摘要:

AbstractRegulation by fetal hypothalamus of adrenocorticotrophic and thyrotrophic function of the fetal anterior hypophysis in the rat was studied by: (1) destruction of the fetal hypothalamic area with an electrocoagulator, (2) compression of the fetal brain by injected paraffin into the fetal skull and (3) induction of fetal exencephaly by hypervitaminosis A in the mother.The body weight of fetuses in which the hypothalamus was damaged was significantly less than that of littermate controls. Volume of the anterior hypophysis was small in fetuses injected with paraffin. The anterior hypophyses were present in all exencephalies, and showed abnormal forms but no reduction in volume. The adrenals were very small in all fetuses in which the hypothalamus was damaged, accompanied by conspicuous shrinkage of cortical cells, while the thyroids were not changed in volume. The height of the follicular cells decreased slightly.The observations suggest that in the late period of fetal life in rats, the hypophysial‐adrenal system is regulated largely by the hypothalamus, but that the hypophysial‐thyroid system is not fully under the control of the hypothala

ISSN:0003-276X    

DOI:10.1002/ar.1091660411

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1970

数据来源: WILEY