摘要:

AbstractThe organization of the sensory innervation of Golgi tendon organs (GTO) fromE. carpi ulnarisof the cat is described. The large Ib afferent fiber gives rise to small myelinated branches which become oriented longitudinally in a neural compartment of the GTO capsule lumen. The latter give rise to smaller, unmyelinated branches which further arborize among loosely packed collagen bundles. The unmyelinated fibers form numerous varicosities and small terminal branches which have portions of the axolemma covered only by basal lamina which intervenes between the collagen bundles and the axolemma. In places, the axon's surface may lack all investments and nerve and collagen come into intimate association. The large unmyelinated branches and their varicosities have different axoplasmic characteristics compared with the small unmyelinated terminal portions. The latter contain few or no mitochondria, vesicles, neurotubules, and neurofilaments. In addition to the description of the terminals, the similarities and differences of the innervation of the GTO, compared with other mechanoreceptors, are discussed.

ISSN:0003-276X    

DOI:10.1002/ar.1091790202

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractThe ultrastructure of articular cartilage of the femoral head was examined in growing male mice of strain C57Bl fed diets containing supplements of 25 or 40% corn oil for periods of 10 days, 2 and 4 weeks and 2 and 3 months. The ration containing 25% corn oil did not produce conspicuous effects. The ration containing 40% corn oil exerted a slight stimulation on the size, the ER, and the mitochondria of the articular chondrocytes. The findings are consistent with the long range effects of oil‐enriched diets on the knee joints of mice and in particular with the failure of such diets to promote the development of osteoarthrosis in mice of strain C57Bl. The results are discussed in relation to earlier observations of the injurious action of diets containing comparable amounts of saturated fa

ISSN:0003-276X    

DOI:10.1002/ar.1091790203

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractEach of the major coronary arteries of 25 fresh sheep hearts was injected with a different colored barium gelatin mass. Histologic sections were made of the AV node and His bundle in nine hearts. The blood supply to this region was traced radiographically, photographically and histologically. X‐rays of the upper ventricular septum were taken before and after coronary injection to demonstrate an os cordis.The sinus node is always supplied by a branch of the right coronary artery. The crux of the heart, and subsequently the AV node, is always supplied by the circumflex artery. The unbranched His bundle, unusually long in sheep, receives a dual blood supply from both the anterior septal branches and the AV node artery. The proximal part of the left and right bundle branches is supplied by the anterior septal branches in the majority of hearts. Intercoronary anastomoses are present in the majority of hearts, particularly in the upper ventricular septum.An os cordis, deep in the atrial septum and directly adjacent to the AV node, was found in all 25 hearts. Occasionally, a second bone was found in the anterior part of the left atrioventricular rin

ISSN:0003-276X    

DOI:10.1002/ar.1091790204

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractThe very fast extraocular muscles have both singly and multiply innervated fibers. The former are among the fastest vertebrate muscle fibers on record, whereas the latter are very slow. In this study single and multiple myoneural junctions were first identified in whole eye muscles of the mouse after staining for cholinesterase. Each group was then embedded separately for electron microscopy. Approximately 10% of the fibers were found to be multiply innervated. The multiple endings and the fibers they innervate resemble those of the tonic bundles of the frog. The majority single endplate is very large in surface view, has sparse junctional folds, and innervates a fiber very rich in mitochondria. These observations were contrary to some frequently held views regarding neuromuscular junctions of very fast fibers. A minority single endplate is smaller, has more junctional folds and innervates a large fiber with fewer and smaller mitochondria.

ISSN:0003-276X    

DOI:10.1002/ar.1091790205

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractThe vaginal epithelium of the normal estrous mouse shows narrow intercellular spaces, many cytoplasmic fibrils and a continuous basal lamina. At 100 days of age, the vaginal epithelium of mice which had received 5 or 20 μg estradiol‐17β, 20 μg ovine prolactin, or 5 μg estradiol‐17β + 20 μg prolactin within the first few days of postnatal life, shows wider intercellular spaces in the middle epithelial layers than occur in normal estrous mice. In addition, the mice receiving 20 μg estradiol‐17β show prominent intercellular spaces in the basal cell layer and interruptions in the basal lamina, which permit penetration of cytoplasmic processes into the subjacent connective tissue. The relevance of these findings to vaginal carcinogenesis

ISSN:0003-276X    

DOI:10.1002/ar.1091790206

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractThe postnatal development of the ovary in the bank vole and vole was investigated in order to determine whether the earlier onset of puberty in the vole coincides with a difference in the speed of gonadal development during the immature period in the two species.The ovarian development differed in three respects: in the vole 4–10% of the germ cells are still oogonia when the animal is born, while in the bank vole oocytogenesis is completed during the embryonic period. Follicles develop earlier and more rapidly in the vole than in the bank vole. The early appearance of fluid accumulation in the follicles and the formation of “fluid sacs” in the vole ovary is character

ISSN:0003-276X    

DOI:10.1002/ar.1091790207

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractUltrastructural changes of rat blastocysts during delayed implantation were studied 16, 20, 24 or 30 hours after estrogen was given to induce implantation.In the inner cell mass the presence of long cytoplasmic processes penetrating deeply into the neighboring inner cell mass cells is seen at 16 hours. Most cells also show an increased number of ribosomes, polyribosomes and granular endoplasmic reticulum.The trophoblast is featured by the formation of large amounts of glycogen and many inclusion bodies. Glycogen granules appear first in some abembryonic trophoblast cells at 16 hours, and spread to the embryonic pole at 24 hours. New inclusion bodies appear sequentially: multivesicular bodies at 20 hours, multigranular bodies at 24 hours and lamellar bodies at 30 hours. The functions of these inclusion bodies remain to be studied.

ISSN:0003-276X    

DOI:10.1002/ar.1091790208

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractExtensive subsurface cisterns were commonly found beneath the apposed plasmalemmas of adjoining hepatocytes in young and adult mice. The cisterns were of two types: (1) flat cisterns, often with ribosomes on their deep surface, and (2) flattened, highly fenestrated smooth surfaced saccules, some of which were in continuity with smooth endoplasmic reticulum. Despite their frequent occurrence, the subsurface cisterns were always absent from the regions of gap or tight junctions, as well as from the periphery of bile canaliculi and cell surfaces bordering the space of Disse. The function of these cisterns remains undetermined.

ISSN:0003-276X    

DOI:10.1002/ar.1091790209

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

摘要:

AbstractThe fine structural appearance of eight spontaneously polyspermic rabbit zygotes was studied. The zygotes were considered polyspermic only after they met all criteria that excluded other possibilities of the trinucleate state. The presence of accessory male pronuclei, with varying degrees of disintegration of their chromatin in zygotes of similar age, suggests that refertilization can occur during an interval of several hours after penetration of the primary sperm. All of the polyspermic zygotes contained cortical granules intermittently beneath the vitelline (plasma) membrane. One zygote possessed cortical granule‐like structures with ill‐defined or no limiting membrane. Formation of enveloping membranes around the incorporated accessory sperm head was precocious since it occurred prior to disintegration of the chromatin. Advanced stages of accessory pronuclei morphologically resembled the primary pronuclei in the same zygote. In seven out of eight zygotes the accessory male pronucleus was separated from the apposing male and female pronuclei. It was concluded that although the fully expanded accessory male pronucleus is similar to the pronuclei of monospermic fertilization, the temporal events of nuclear envelope formation were distur

ISSN:0003-276X    

DOI:10.1002/ar.1091790210

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY

ISSN:0003-276X    

DOI:10.1002/ar.1091790201

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1974

数据来源: WILEY