摘要:

AbstractAdult male and female southern grasshopper mice (Onychomys torridus) were tested for predatory aggression toward cricket prey 1 hr after single injections of d‐amphetamine (1 or 10 mg/kg) or 1‐amphetamine (1 or 10 mg/kg). At the lower dose, d‐amphetamine decreased feeding behaviors, while I‐amphetamine altered attack‐related behaviors. At the higher dose, both stereoisomers appeared to be equipotent in significantly decreasing 5 measures of predatory aggression. These results suggest that brain dopamine and norepinephrine play important roles in the regulation of predatory aggression of Onychomys

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<99::AID-AB2480020202>3.0.CO;2-G

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

摘要:

AbstractOnychomys leucogaster (northern grasshopper mice) were induced to kill mice with response‐contingent shock, and the effects of several physiological, pharmacological, and endocrinological variables were assessed. Lesions of the septum facilitated mouse killing, while lesions of the amygdala abolished spontaneous mouse killing and delayed shock‐facilitated killing. Chlorpromazine (2.5–5 mg/kg) and chlordiazepoxide (5–10 mg/kg) facilitated mouse killing on postdrug trials but did not affect killing when the animals were drugged. Adrenalectomy, castration, and castration adrenalectomy did not alter the frequency of kill nor were sex‐related differences in killing noted. These results were compared to those found by others studying the effects of lesions and drugs on mouse killin

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<107::AID-AB2480020203>3.0.CO;2-B

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

摘要:

AbstractRepresentative agents from all of the major classes of drugs that have been reported to be selective antagonists of spontaneous mouse‐killing behavior (i.e., antidepres‐sants, antihistamines, anticholinergics, and stimulants) were tested for their ability to antagonize the mouse‐killing response in rats that became killers following removal of the olfactory bulbs (O.B. lesion‐induced killer rat) and in spontaneous killers. All of the drugs tested selectively antagonized the killing behavior of both spontaneous and lesion‐induced mouse‐killing rats. Several drugs (i.e., imipramine, amitriptyline, d‐amphetamine, and chlorpheniramine) were found to be significantly less potent antagonists of mouse killing in the 0.6. lesioned rat as compared to spontaneous killers. Since all of the drugs that exhibited significant differences in activity between the two models have been shown to possess the ability to elevate norepinephrine levels at receptor sites in the brain, alterations in noradrenergic systems may account for the differences in sensitivity that were observed in this study. The possibility that there may be a common neural substrate for mouse killing in the two models

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<123::AID-AB2480020204>3.0.CO;2-I

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

摘要:

AbstractA series of experiments was designed to examine the role of central cholinergic mechanisms in shock‐induced aggression. Cholinergic blockade in the basolateral amygdala, ventral hippocampus, or dorsal hippocampus resulted in greatly reduced levels of fighting in response to footshock. However, while pain sensitivity remained unaltered in the amygdala group, both of the hippocampal groups exhibited decreased shock sensitivity. Further investigation of the amygdala revealed (1) increased fighting in response to increased cholinergic levels, (2) neuroanatomical specificity to the basolateral division of this complex, (3) that an intact basolateral amygdala is essential to the normal manifestation of shock‐induced aggression, and (4) that social attraction remains unaltered by cholinergic blockade of the basolateral amygdala. Motor coordination and motor activity were not significantly affected in any treatment condit

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<131::AID-AB2480020205>3.0.CO;2-K

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

摘要:

AbstractForty male undergraduates were provoked following their ingestion of high or low doses of either alcohol or delta‐9‐tetrahydrocannabinol (THC). The expression of physical aggression was related to the quantity of alcohol ingested. The high dose of alcohol instigated more intense aggression than the low dose. The high dose of THC, on the other hand, did not increase aggressive behavior. In fact, it tended to produce a weak suppression eff

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<153::AID-AB2480020206>3.0.CO;2-9

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<163::AID-AB2480020207>3.0.CO;2-5

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<164::AID-AB2480020210>3.0.CO;2-M

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<166::AID-AB2480020211>3.0.CO;2-D

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<169::AID-AB2480020212>3.0.CO;2-1

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY

ISSN:0096-140X    

DOI:10.1002/1098-2337(1976)2:2<176::AID-AB2480020213>3.0.CO;2-6

出版商:Wiley Subscription Services, Inc., A Wiley Company    

年代:1976

数据来源: WILEY