摘要:

&NA;The five‐year survival rate in 72 patients who underwent treatment for squamous‐cell carcinoma of the anus in Stockholm County (1972 to 1978) has been studied. There were no differences in survival rates after rectum‐preserving treatment (mainly consisting of irradiation±cytostatics ±local excision) as compared with extensive surgery (abdominoperineal resection), even if the tumor size, location, and differentiation were taken into consideration. It therefore seems appropriate to suggest irradiation±cytostatics as the therapy of choice regardless of size, location, and differentiation of the tumor.

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

摘要:

&NA;Colonic mucosa in 62 patients with familial polyposis coli (FPC) was stained by a Periodic Acid‐Thionin Schiff/Potassium Hydroxide/Periodic Acid‐Schiff®method in which the normal colonic mucosa usually stained red and carcinoma stained blue or purple. In FPC, 82.2 percent stained blue or purple, whereas 38.8 percent stained blue or purple in normal controls. The data suggest that sialomucin properties of the normal‐appearing flat mucosa in FPC are different from those of the normal colon, and that this simple technique may be useful for the early detection of high‐risk individuals in the FPC family.

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

摘要:

&NA;To find and eradicate synchronous neoplasms, colonoscopy was performed before and after resectional surgery in 50 patients with “occluding colorectal cancer,” defined as encroachment of the lumen by tumor to a degree that prevented passage of a colonoscope. Synchronous, frequently multiple adenomas were found in 29 (58 percent) of these patients. Three patients (6 percent) had synchronous invasive cancer as well. None of these lesions was detected by intraoperative palpation, even though 46 percent of them measured more than 1.0 cm in diameter. Synchronous neoplasms were found significantly more often in patients with occluding cancer than in patients with non‐occluding cancer, investigated concurrently at the same hospital. The former patients appear to be in double jeopardy with respect to synchronous neoplasms, these being more prevalent and less accessible than in patients with non‐occluding tumors. Moreover, most of the synchronous lesions are undetectable by palpation. These findings bear out the importance of early postoperative, as well as preoperative, colonoscopy in all patients with occluding colorectal cancer.

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

摘要:

&NA;A survey of 322 ileostomates was undertaken to assess the impact of an ileostomy and determine problems that are encountered by patients. Most patients (72 percent) felt they led normal lives with the ileostomy and encountered fewer restrictions in life‐style than with their disease. However, only 35 percent of patients felt their ileostomies functioned perfectly. Skin irritation (49 percent), offensive noise and odor (42 percent), detection of the appliance (17 percent), and difficulty in handling the appliance (29 percent) were some of the problems encountered. Psychologic problems were related to poor body image (22 percent) and sterility or impotence (12 percent). All of these problems, however, were less than had been anticipated. Various sources of information were available to the ileostomate. However, about 50 percent of patients felt they received inadeoquate preoperative information or counseling.

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

摘要:

&NA;A consecutive series of 35 patients with acute obstruction due to carcinoma of the left colon (29) or rectum (six) were treated by primary resection with anastomosis. The operation usually took the form of a left hemicolectomy or sigmoid resection without a proximal colostomy. There were three operative deaths (8.5 percent) due to anastomatic dehiscence, bronchopneumonia and pulmonary embolism, respectively. Nonlethal complications occurred in ten patients (analystomotic leakage in three, a ureteric fistula in one, and wound infection in six). The mean duration of hospital stay in patients without complications was 18 days (range, 12 to 35). The morbidity and mortality in this series did not exceed the cumulative morbidity and mortality that would be expected after staged surgery. Compared with staged surgery, immediate resection and anastomosis, by avoiding the problems of colostomy and reducing the length of hospital stay, have significant advantages for the patient.

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID

摘要:

&NA;A routine clinicopathologic (CP) staging system for patients who have had surgical resection for colorectal carcinoma was established at Concord Hospital in 1971. Research on this prospective series of resections has evaluated the CP staging system as a guide to prognosis. The aim of this study was to compare the CP system with the classic Dukes' staging system and its modified form introduced by Astler and Coller to determine which method provided the most accurate basis for prognosis. Life table survival analysis was used to examine the survival of 709 patients according to each staging system. Relative mortality rates for groups of patients cross‐classified by each possible pair of staging systems were examined and the Cox regression model was used to determine the independent effects of staging by each system on survival. The CP system was found to have a stronger association with survival than either the classic Dukes' system or the Astler‐Coller modification of the Dukes' system. The importance of supplementing data on the operative specimen with data about the spread of tumor beyond the limits of surgical resection, is emphasized

ISSN:0012-3706    

出版商:OVID    

年代:1985

数据来源: OVID