摘要:

&NA;The detection of tumors with radiolabeled antibodies against CEA is possible; however, current nuclear medicine scanning cameras rarely detect tumors smaller than 2 cm in diameter. One of the limitations to tumor detection is the inability to place a detecting camera near a deeply seated intra‐abdominal tumor. A hand‐held gamma‐detecting probe, suitable for intraoperative use, was designed to locate radioactive tumors. Experimental work with CEA‐producing colon tumor xenografts in nude mice suggests this probe is more sensitive than external scanners in detecting small tumors. A case report documents the clinical use of this new intraoperative probe.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;Preoperative biopsies and colectomy specimens from 40 patients with long‐standing ulcerative colitis (of whom 20 had adenocarcinoma at colectomy) were searched for the presence of villous adenomatous changes with or without cellular dysplasia. Villous adenomatous changes were found in available preoperative punch biopsies in nearly 70 per cent of the patients with carcinoma, but in none of the preoperative punch biopsies from the 20 patients without cancer. Only three of the preoperative biopsies from patients with carcinoma showed severe dysplasia, and also one of the 20 colitic patients without carcinoma. The mucosal tip in villous edenomatous changes was usually covered by columnar epithelium without dysplasia. In preoperative punch biopsies from patients with long‐standing ulcerative colitis, the presence of structures compatible with villous adenoma—even those without cellular dysplasia—should be considered an ominous histologic sign and, thus, an indication for panproctocolectomy.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;Sequential analysis of a double‐blind clinical trial involving 26 patients demonstrated a statistically significant superiority of ceruletide over metroclopramide in restoring peristalsis in intestinal paralysis after abdominal surgery (P<0.05).

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;In a case‐control study of cholecystectomy and carcinoma of the colon conducted in a residential retirement community near Los Angeles, California, no significant association was found, either for all colonic cancer (relative risk=1.2) or by subsite (relative risk=0.8 for right‐sided colonic cancer and 1.3 for other colonic cancer). Because of this negative finding and the inconsistency of other epidemiologic studies, certain aspects of the descriptive epidemiology of colonic cancer in Los Angeles were examined to see if they were consistent with a major etiologic role for cholecystectomy. The distribution of right‐sided colonic cancer by sex and race contrasted sharply with that expected, based on the known distribution of cholecystectomies in the population. Cholecystectomy is unlikely to be an important factor in the etiology of right‐sided colonic cancer.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;Damage to the ureter is uncommon. In this series, the damage has been either elective, accidental or delayed. In the occasional patient the damage was repaired, but in most a nephrectomy was necessary.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;Eighty patients undergoing elective major colorectal surgery were nutritionally assessed using simple anthropometric methods and serum albumin. Although most of the patients were not malnourished, these tests were able to detect a small group of high‐risk patients. Thirty major complications were recorded. The incidence of complications was 72 per cent in patients with low body weight, 69 per cent with low forearm muscle circumference, 55 per cent with recent weight loss, and 57 per cent with serum albumin below 35 g/l. Anthropometric tests were better in predicting postoperative complications than serum albumin. Of those patients who developed complications, 60 per cent had low grip strength, 37 percent weight loss, 37 per cent high malnutrition score, 33 per cent low body weight, and 27 per cent had lower serum album. Anthropometric tests were more sensitive and more accurate than serum albumin. Anthropometry has the additional advantages of being simple, noninvasive, and independent of laboratory facilities; it also provides instant bedside assessment.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID

摘要:

&NA;Acute intestinal obstruction was the presenting feature in 124 (19 per cent) of 646 patients with colorectal carcinoma seen over a six‐year period. Forty‐two per cent of tumors were incurable at presentation. Obstruction was complicated by perforation in 22 patients (18 per cent). Only 15 per cent of tumors occurred in the rectum. Although the postoperative mortality rate was higher in patients with coincidental perforation than in those without (52 vs. 26 per cent:P=0.03), five‐year survival rates were the same: 18 per cent overall, rising to 29 to 34 per cent after “curative” resection. Five‐year survival rates were best for right colon tumors and worst for rectal tumors (36 vs. 5 per cent:P=0.01). The overall hospital mortality rates for colostomy and delayed resection, resection with colostomy, and resection with anastomosis were equivalent (18 to 22 per cent), but following “curative” resection the hospital mortality rate was higher for resection with colostomy than with other treatments (29 vs. 15 per cent), since two patients died following early colosure of colostomy. Five‐year survival was better following resection with anastomosis (48 per cent) than staged procedures (18 per cent:P=0.01), since two patients died following late closure of colostomy.

ISSN:0012-3706    

出版商:OVID    

年代:1984

数据来源: OVID