摘要:

&NA;Stereologic methods were used to determine the amount of growth of colonic adenomatous polyps. Epithelial surfaces were increased from 12 to 226 times compared with the normal mucosa of origin, including the epithelium of the crypts. The number of cells was increased from 12 to 370 times. The supposed villi of the polyps are in reality branched folia, and the crypts between them are slit‐like, permitting flow of ingesta through them. The increase in the number of cells is not primarily dependent on mitotic activity but more on amitotic nuclear fragmentation

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;In certain cases of advanced (incurable) colonic cancer, a cecalsigmoid anastomosis may relieve actual or impending bowel obstruction. In this way, a colostomy can be avoided and the patient may improve symptomatically. An illustrative case is briefly presented.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;The magnetic ring device implanted in an attempt at achieving continence in the colonic stoma, consists of a subcutaneous ring and a removable magnetic cap with a charcoal filter. Fourteen patients were selected from a potential number of 58 candidates. Fifty per cent of the patients have had good results. No complications were attributable to the implanted device. There was no incidence of parastomal hernia.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;Sixty pregnancies in 31 ulcerative colitis patients were studied retrospectively. Twelve patients (20 per cent) improved, 11 (18.3 per cent) deteriorated, while in 37 (61.6 per cent) there was no change during pregnancy. Seven pregnancies (13.7 per cent) ended by spontaneous and two by artificial abortions. There were 50 full‐term deliveries and one premature birth. Seven of the patients were treated with sulfasalazine; five were given steroids; and two, azathioprine. All gave birth to normal children. Of unplanned pregnancies 38.4 per cent were associated with activity of the disease versus only 12 per cent of planned gestations. Pregnancy does not seem to aggravate the course of pre‐existing ulcerative colitis, nor does the colitis interfere with the outcome of the pregnancy.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;In an attempt to identify those patients who would benefit from palliative resection of the colon or rectum and those who would not, an analysis of ten years of resections was undertaken. For the 81 patients who underwent palliative resection, the operative mortality was 10 per cent and the postoperative morbidity was 50 per cent. The mean survival was 11.4 months and the median survival nine months. Poor prognostic factors deduced were patients with extensive liver metastases, those over the age of 75 years, and a previous history of cardiovascular disease. It is believed that patients with a combination of these factors may not benefit from palliative resection. Otherwise, resections satisfactorily relieve patients of the symptoms of impending obstruction and rectal bleeding and are, therefore, believed to be worthwhile.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;In the 18‐year period between 1960 and 1978, only 20 cases of carcinoma of the anus were recorded in the Cancer Registry of the University College Hospital, Ibadan, Nigeria; of these 18 were treated in the hospital. This paper is an analysis of the clinicopathologic features and outcome of treatment of ten patients whose records could be traced. There was a slight female predominance, with anal canal tumors being more common than anal margin tumors. Most cases were advanced when first seen and the commonest manifestations were passage of mucoid stool, with blood and anal pain. The tumors tended to grow circumferentially and could be confused with anorectal tuberculosis, schistosomiasis, and lymphogranuloma venereum. Prognosis was better with anal margin tumors

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;The effect of duration of symptoms and other prognostic factors on survival was studied by interview using a population‐based sample of 154 colorectal cancer patients. The authors found that symptom durations of up to approximately one year before diagnosis had no effect on survival. In addition, it was found that the total number of symptoms was a statistically significant predictor of survival, although no single symptom had a significant effect. Stage, sex, and site also were found to be significant predictors of survival, whereas age, socioeconomic status, and other factors were not predictive.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

&NA;The treatment of inflammatory bowel disease has gone through a dramatic evolution in the last 40 years. Although the medical treatment has shown little progress during this time, surgical concepts have continued to change. Resection of the disease with formation of a well‐functioning ileostomy stoma was a great milestone. In recent years, the development of an internal reservoir with a continent ileostomy has greatly improved the status of these patients. However, a pelvic reservoir, using the natural anorectal sphincter, may well be the next step in this evolutionary process.

ISSN:0012-3706    

出版商:OVID    

年代:1981

数据来源: OVID