摘要:

AbstractKeratin, a fibrous protein in eukaryotic epithelial cells, consists primarily of intermediate filaments, of which at least 19 immunologically distinct proteins have been characterized. The identification of keratin is essential to establishing the epithelial origin of a given cell type or its tumor derivatives. Histologic tinctorial tests for keratin have not been widely applied because of lack of specificity and sensitivity. Rhodamine B fluorescence demonstrates well differentiated keratin in many epithelial cells and tumors. Immunocytochemical staining with broad range antibodies and epithelial membrane antigen demonstrates most epithelial moieties. By electron microscopy, the identification of tight junctions, desmosomes and tonofibrils helps establish the epithelial lineage of a tumor. (The J Histotechnol14:51, 1991)

ISSN:0147-8885    

DOI:10.1179/his.1991.14.1.51

出版商:Taylor&Francis    

年代:1991

数据来源: Taylor

摘要:

AbstractThe utility of immunostaining as an aid to identify metastatic carcinoma cells in lymph nodes was demonstrated by the presentation of a case of infiltrating lobular carcinoma of the breast with subtle lymph node metastasis. Immunohistochemical staining of the lymph nodes with anti AE1/AE3 vividly detected otherwise inapparent carcinoma cells. (The J Histotechnol14:57, 1991)

ISSN:0147-8885    

DOI:10.1179/his.1991.14.1.57

出版商:Taylor&Francis    

年代:1991

数据来源: Taylor

ISSN:0147-8885    

DOI:10.1179/his.1991.14.1.59

出版商:Taylor&Francis    

年代:1991

数据来源: Taylor

ISSN:0147-8885    

DOI:10.1179/his.1991.14.1.61

出版商:Taylor&Francis    

年代:1991

数据来源: Taylor

ISSN:0147-8885    

DOI:10.1179/his.1991.14.1.63

出版商:Taylor&Francis    

年代:1991

数据来源: Taylor