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11. |
AztreonamA Review of the First Monobactam |
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The American Journal of the Medical Sciences,
Volume 302,
Issue 1,
1991,
Page 46-49
ELLA WESTLEY-HORTON,
JAMES KOESTNER,
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PDF (402KB)
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ISSN:0002-9629
出版商:OVID
年代:1991
数据来源: OVID
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12. |
Septic Shock |
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The American Journal of the Medical Sciences,
Volume 302,
Issue 1,
1991,
Page 50-65
ANTHONY NOGARE,
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PDF (1795KB)
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摘要:
Septic shock (SS) is the most common type of shock encountered by internists, and its prevalence appears to be increasing. SS complicates all types of infections. The hemodynamic characteristics of SS include a low systemic vascular resistance and an elevated, but relatively inadequate, cardiac output. A cardiomyopathy frequently occurs. The major endogenous mediator of SS is tumor necrosis factor, and interleukins-1 and −2 may also contribute. Important secondary phenomena include release of platelet activating factor, vasodilator prostaglandins, and upregulation of adhesion molecules on polymorphonuclear leukocytes and endothelial cells. Current therapy is often ineffectual, and potentially promising new therapeutic approaches are reviewed.
ISSN:0002-9629
出版商:OVID
年代:1991
数据来源: OVID
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