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11. |
Pharmacologic Therapy for Human Immunodeficiency Virus InfectionA Review |
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The American Journal of the Medical Sciences,
Volume 307,
Issue 5,
1994,
Page 368-373
KATHLEEN NEUZIL,
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PDF (658KB)
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ISSN:0002-9629
出版商:OVID
年代:1994
数据来源: OVID
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12. |
EditorialShould Intensive Care Be Limited for Patients With Self‐Induced Disease? |
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The American Journal of the Medical Sciences,
Volume 307,
Issue 5,
1994,
Page 374-377
PETER TERRY,
HENRY FESSLER,
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PDF (498KB)
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ISSN:0002-9629
出版商:OVID
年代:1994
数据来源: OVID
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13. |
Southwestern Internal Medicine ConferenceEndothelial Dysfunction and Vascular Disease |
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The American Journal of the Medical Sciences,
Volume 307,
Issue 5,
1994,
Page 378-378
ROBERT MEIDELL,
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PDF (1432KB)
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摘要:
Vascular endothelial cells, critically situated at the blood-tissue interface, exert important effects on vascular tone and permeability, regulate the coagulation and fibrinolytic systems, mediate translocation of inflammatory cells to the tissue compartment, and modulate proliferation of vascular smooth muscle cells. As the physiology of the endothelium has been defined, defects in endothelial function have been identified in association with human disease, and a syndrome of dysfunctional endothelium has been described. Although it remains debatable whether a coherent syndrome of endothelial dysfunction exists, disordered endothelial biology appears to contribute to the pathophysiology of human vascular disease. Identification of specific molecular mechanisms offers potential targets for novel therapeutic interventions, including genetic modification of endothelial cells in vivo.
ISSN:0002-9629
出版商:OVID
年代:1994
数据来源: OVID
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