摘要:

An autopsy case associated with both male breast cancer and hepatocellular carcinoma in which serum &agr;-fetoprotein (AFP) was extremely elevated is described. The source of AFP production was investigated. In lectin-affinity chromatography of the patient’s serum, concanavalin A (ConA) binding pattern was not consistent with that of hepatocellular carcinoma, and lens culinaris agglutinin A (LCA) affinity indicated a similar pattern to hepatocellular carcinoma. The immunohistochemistry staining for AFP revealed positive reactivity in breast cancer cells, but was negative in hepatocellular carcinoma cells. To the best of our knowledge, there have been no reports of breast cancer exhibiting immunohistochemically positive AFP in breast cancer cells. In the present case, ConA binding test was useful for identification of the source of AFP production. Furthermore, corresponding aggravation of breast cancer to the elevation of AFP suggested the possibility that AFP might enhance breast cancer growth.

ISSN:0002-9629    

出版商:OVID    

年代:2001

数据来源: OVID

摘要:

Hemodialysis patients are known to develop the complication of extrapulmonary tuberculosis more frequently than the general population. Tuberculous arthritis is a rare form of extrapulmonary tuberculosis and is reported to occur in approximately 1% of cases in nonuremic patients. Only 3 cases in dialysis patients, who were not proven by a bacterial culture or had died before treatment, have been reported. We report herein a culture-proven case of tuberculous arthritis developing at the sternoclavicular joint, which initially mimicked an apparent neoplasm in a hemodialysis patient. A favorable outcome was obtained after antituberculous therapy. Tuberculosis must be considered one of the most significant diagnoses in hemodialysis patients who present with a tumor-like lesion.

ISSN:0002-9629    

出版商:OVID    

年代:2001

数据来源: OVID