摘要:

(Editor's Note: This Medical Classic is reprinted in its entirety, followed by an invited commentary by Nicholas P. Christy, M.D. It appeared in AJMS 139; 473–84. 1910.

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

This essay is not a history of the pituitary gland, or an abbreviated life of Cushing, or a comprehensive review of hypophysial endocrinology. What is attempted is a short evaluation of this medical “classic” as a contribution to the history of ideas about the function of the anterior pituitary and about clinical disorders of the gland. [Am J Med Sci 1981; 281(2):79–96.]

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

Twenty-one patients with severe coccidioidomycosis, including eight with osseous lesions, were admitted to the University of California, Davis, Medical Center, during a recent epidemic. Transient mild ionized hypercalcemia occurred in only two patients, and a tendency toward low normal ionized calciums was noted. Parathyroid hormone levels appeared to be appropriate for the ionized calcium in these patients. There were no significant differences in ionized calcium levels of parathyroid hormone levels among patients with and without osseous coccidioidomycosis. We conclude that hypercalcemia is rare in coccidioidomycosis, even with extensive bony involvement. (Am J Med Sci 1981; 281(2):97–99.)

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

Methicillin-resistant Staphylococcus aureus (MRSA) bacteriuria was detected in 11 of 41 patients colonized or infected with MRSA. The patients with bacteriuria generally were older than 40 years of age, five were diabetic, seven had prior indwelling urethral catheters, two had undergone other urologic manipulations, and only one was clinically symptomatic. Eight patients received variable combinations of antibiotic therapy prior to the diagnosis of MRSA bacteriuria, and seven were still on antibiotic therapy at the time the bacteriuria was detected. Bacteriuria lasted four days to 14 weeks, and was eradicated promptly with cephalosporin therapy in five of six patients. Bacteriuria in the untreated patients cleared spontaneously in one month. A single MRSA serotype (83A) predominated. The MRSA isolates were resistant in vitro to most antibiotics except vancomycin. Resistant colonies were observed within cephalothin disc zones of inhibition at 30C (resistance was confirmed by microtube-dilution sensitivity testing). MRSA disc sensitivity testing for cephalothin may be unreliable when performed at 35C. (Am J Med Sci 281(2):101–109.)

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID

摘要:

A young woman with fever and pleural effusion eventually was found to have both primary tuberculosis and systemic lupus erythematosus. Before either diagnosis was confirmed, the patient had a dramatic defervescence in response to prednisone; her condition had not improved initially after anti-tuberculous therapy, Uncertainty regarding the cli n ica I significance of this remarkable temperature response led us to review our experience with febrile tuberculous patients who had received corticosteroids. Of 14 such patients, nine had rapid declines of body temperature to below 36.56. In a comparable group of 14 patients with a varietyof connective tissue diseases, 12 showed an equally dramatic defervescence after corticosteroid administration. The data suggest that a prompt temperature decline following corticosteroid therapy is a nonspecific response that cannot be used to differentiate between fever of infectious or noninfectious origin.

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID

ISSN:0002-9629    

出版商:OVID    

年代:1981

数据来源: OVID