摘要:

Blood pressure of hypertensive subjects reacts differently from that of borderline or normal subjects at rest in either sitting or lying positions. In the hypertensive group the diastolic pressure tends to rise more on consecutive measurements and the systolic blood pressure tends to fall less than in the two other groups. Similarly, on going from the lying to the sitting position, diastolic blood pressure of hypertensives rises less than that of normotensive or borderline hypertensive individuals. Thus, people with 'casual' hypertension differ in their reaction to rest and changes in body position in their reaction to rest and changes in body position with respect to normotensives or borderline hypertensives. This behavior could lead to labelling of subjects as 'normal' or 'hypertensive' depending on position and timing of the blood pressure measurement.

ISSN:0002-9629    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

In order to further identify the stressful conditions associated with a sudden, pronounced drop in serum iron concentration, a concomitant rise in white blood cell count was utilized to select the charts of 47 patients for review. These patients were grouped into the four categories of surgical, infectious, neurologic, and obstetric events. The rapid drop in serum iron concentration appeared to be a non-specific response to a variety of stressful situations, and possible mechanisms are discussed.

ISSN:0002-9629    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Two antihypertensive agents that inhibit sympathetic activity by differing pharmacologic mechanisms, the centrally-acting alpha-adrenergic agonist, clonidine, and the peripheral alpha-adrenergic antagonist, prazosin, were compared and also given in combination in 24 patients with essential hypertension. The patients were randomized into two groups; 11 received chlorthalidone (50mg) daily throughout the protocol, whereas 13 received no diuretic. In the 13 patients not receiving the diuretic, supine mean blood pressure fell by 11.0±3.5 mmHg (p<0.01) with clonidine (0.3 mg daily), 5.5±2.9 mm Hg (p<0.05) with prazosin (15 mg daily), and 12.7±5.2 mm Hg (p<0.02) with the combination. In the 11 patients concurrently receiving chlorthalidone, supine mean blood pressure fell by 9.5±2.0 mm Hg (p<0.01) when clonidine was added, 2.3±1.9 mm Hg (ns) when prazosin was added, and 7.9±2.1 mm Hg (p<0.01) with the combination. In both the presence and absence of concurrent diuretic treatment, the blood pressure-lowering effects of clonidine were greater than those of prazosin, but were not different from the antihypertensive effects of the combination of clonidine and prazosin. Therefore, the simultaneous administration of clonidine and prazosin in the doses used in this study does not appear to be more effective than clonidine alone in the treatment of patients with hypertension.

ISSN:0002-9629    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Clinical, angiocardiographic and necropsy data in a case of congenitally corrected L-transposition of the great vessels complicated by constrictive pericarditis are described. Isolated cases of constrictive pericarditis superimposed on congenital heart lesions have been reported and are rare; however, a coexistence with corrected transposition has not been previously reported to our knowledge. These disorders were demonstrated concurrently with angiocardiography in our patient and confirmed on pathologic examination.

ISSN:0002-9629    

出版商:OVID    

年代:1983

数据来源: OVID

摘要:

Seven cases of leishmaniasis, including a fatal case of visceral leishmaniasis and 6 cases of dermal leishmaniasis, were seen in Boston over a four-year period. Diagnosis was made by isolation of organisms in culture or by identification of organisms in stained preparations of tissue. Proper management of patients with leishmanial infections requires an appreciation of the geographical strain differences of each species.

ISSN:0002-9629    

出版商:OVID    

年代:1983

数据来源: OVID