ISSN:0001-6349    

DOI:10.3109/00016347509156328

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract.The dietary habits of 94 pregnant women (median age 26 years) were studied by means of four‐day dietary records. Twenty‐seven women were followed longitudinally and were observed in the 10–15th, the 24–27th and the 34–37th week of gestation (L‐series). The remaining 67 women comprised the A‐series. of which 20, 32, and 15 made their records during the 10–15th. 24–27th, and 34–37th week of gestationt respectively. There were no significant differences between the results from these two series. The mean daily energy intake was 2360 kcal and remained unchanged during pregnancy, exceeding by 250 kcal the average intake in non‐pregnant women in Gothenburg, studied earlier.The iron intake comprised 1–2 mg of haeme iron, about 10 mg of native non‐haeme iron and 5–6 mg of fortification iron. The mean iron intake was 7.2 mg/1000 kcal, which is below the recommendation, but it was distributed over the food groups in a manner more favourable for iron absorption than in the average Swedish population. Further effects to improve the diet so as to increase the content of iron and factors known to favour iron absorption are desirable. The results justify the normal practice of prescribing suppleme

ISSN:0001-6349    

DOI:10.3109/00016347509156329

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract.In 22 healthy women the non‐haeme iron absorption (bone‐marrow smears and haematological parameters) was studied at the 12th, the 24th and the 36th week of gestation and two months after delivery.In eight non‐pregnant women and in seven pregnant women (at the 36th week of gestation) the absorption of food iron was measured from different types of meals. The iron absorption was measured from radioironlabelled test meals using a whole‐body counter with a very high sensitivity.During pregnancy the non‐haeme iron absorption increased continuously from Less than 1 % in early pregnancy to almost 15 % in late pregnancy. Calculations indicated that the amount of iron absorbed from the diet covered only about half of the demands.The increasing absorption of food iron during pregnancy seems to be related to the still more increasing demands. However, the very low absorption values in early pregnancy was quite unexpected. The amount of iron absorbed was actually below the basal demands, which means that even in early pregnancy, for reasons unknown, there is a negative iron balance. Further studies are necessary to elucidate the significance of this finding.Two months after delivery the absorption of iron from the diet was increased compared to in non‐pregnant women and exceeded the demands at that phase thus indieating that a positive iron balance w

ISSN:0001-6349    

DOI:10.3109/00016347509156330

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract.The absorption of non‐haeme iron in the food and from a 3 mg reference dose of ferrous iron in solution was measured in 17 healthy women before the 12th week of gestation and in 13 of the women two months after legal abortion.The absorption of ferrous iron in solution was calculated from determinations of the55Fe activity in blood samples. The food iron absorption was measured from59Fe‐labelled test meals using a highly sensitive whole‐body counter. In addition bone‐marrow smears and other haematological parameters were studied.The median value of the absorption from the non‐haeme food iron was 2.5 % and from the ferrous iron salt 10.0 % in early pregnancy in women with storage iron. Two months after abortion the absorption increased to 12.6 and 42.6 % respectively. In early pregnancy the absorption of iron was higher in women without stainable iron in bone‐marrow smears. The present results confirm previous observations that the absorption of food iron in early pregnancy is lower than the basal daily requirements. The low absorption is only partly explained by the reduced requirements of iron in early pregnancy. Some other factors related to pregnancy seem also to

ISSN:0001-6349    

DOI:10.3109/00016347509156331

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY

摘要:

Abstract.Iron absorption, bone‐marrow smears and haematological parameters were repeatedly studied during pregnancy in 50 women. The same studies were repeated two months after delivery. The material was randomly divided into two groups. Twenty‐four women were treated with 200 mg of ferrous iron daily while 26 were given placebo. The iron absorption was measured from radioiron‐labelled test doses of 100 mg ferrous iron in a whole‐body counter with high sensitivity.In the placebo group the iron absorption increased throughout pregnancy from an average of 6.5 % at the 12th week to 14.3 % at the 35th week of gestation. Two months after delivery the absorption was higher than initially. In the iron‐treated group the absorption increased between the 24th and 35th week of gestation from 6.0 to 8.6 %. After delivery 5.5 % of the test dose was absorbed.The haemosiderin iron in the bone‐marrow was mobilized during pregnancy. In the placebo group no woman had more than trace of haemosiderin in the bone‐marrow smears at the 35th week of gestation. In the iron‐treated group 65 % had the same bone‐marrow findings. The amount of bone‐marrow haemosiderin at term seems not to have the same significance for the diagnosis of iron deficiency in pregnancy as in non‐pregnant subjects. Two months after delivery about 50 % of the women in the placebo group had restored their iron depots. In the iron‐group the haemosiderin content in the bone‐marrow smears was enhanced in most women compared to early pregnancy. In the placebo group haematoLogical data indicated a high frequency of iron deficiency in late pregnancy while in the iron‐treated group ir

ISSN:0001-6349    

DOI:10.3109/00016347509156332

出版商:Blackwell Publishing Ltd    

年代:1975

数据来源: WILEY