摘要:

Abstract.A study of labor induction in 325 patients is reported.Group I(77 patients with Bishop's scores 0‐6)and 2(69 patients with Bishop's scores 7‐12) were given 0.5 mg prostaglandin E2every half hour (maximum 5 mg per day).Group 3(87 patients with Bishop's scores 0‐6) was given 50 International units of buccal desaminooxytocin every half hour (maximum 500 International units per day). InGroup 4(92 patients with Bishop's scores 7‐12), labor was induced by primary amniotomy and automatic oxytocin infusion by the Cardiff method.In groups 1, 2 and 3, 45 per cent, 74 per cent and 41 per cent delivered within 48 hours, while 100 per cent in group 4 delivered within 24 hours.No differences were found in either the frequency of cesarean section or the incidence of low Apgar scores.A higher, but not statistically significant frequency of vacuum extraction was found in the Cardiff group (25 per cent) than in the tablet‐induced groups (15 per cent). There was, however, a significantly higher occurrence of alterations in fetal heart rate which led to instrumental intervention to hasten delivery in the Cardiff group compared to the tablet‐induc

ISSN:0001-6349    

DOI:10.3109/00016347909154590

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.By comparing the condition of the cervix at the time of a cesarean section with the findings at subsequent hysterography in 68 patients, it is considered likely that the thickness of the scar depends primarily on the thickness of the lower uterine segment at the time of the section and on the site of the incision. The prognostic significance of these findings is discussed on the basis of a theoretical approach to the development at or near the scar of previous cesarean section.

ISSN:0001-6349    

DOI:10.3109/00016347909154591

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Ten women in the last trimester of a normal pregnancy were subjected to five different loads in a cross‐over study. Fetal breathing movements (FBM), fetal heart rate (FHR), maternal heart rate (MHR), and mean arterial pressure (MAP), maternal transcutaneously measured pO2(Tc‐pO2), and the energy supply to the Tc‐pO2electrode were recorded continuously before, during, and after the load. Maternal capillary pH and pCO2were measured at three representative time points. The immediate responses of the incidence of FBM to the different challenges were: increase after dynamic work (bicycle test); no change after static work (isometric muscle contraction) and passive movements; decrease after hyperventilation and hyperoxygenation. FHR was unaffected by all challenges. The FBM incidence varied in parallel with pCO2after dynamic work and hyperventilation and inversely with the Tc‐pO2rise caused by hyperoxygenation. Maternal pH was increased after passive movements (no change in FBM) and after hyperventilation (decreased incidence of FBM). FBM seem to be more sensitive to environmental changes than is the FHR. Mechanical stimuli to the uterus were not responsible for the augmentation of FBM seen after the bicycle test. The present observations reveal the multifactorial nature of the regulation of FBM, and support the role of CO2as a major stimulator of breathing movements also in prenat

ISSN:0001-6349    

DOI:10.3109/00016347909154592

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The effect of a folic acid supplement on birth weight and placental weight in women delivering in the early summer in Denmark was investigated.Thirty‐six women with normal pregnancy and expected delivery in the first half of June were selected consecutively. They were paired two and two, and allotted to two groups, one of which was supplied daily with 5 mg folic acid, and the second with tablets without folic acid, from the 23rd week of pregnancy. A significant correlation was found between erythrocyte folic acid and birth weight. The infants in the folic acid group were 12.7 per cent heavier than those in the control group (p<0.01). A similar difference was found with regard to placental weight and the number of placental cell

ISSN:0001-6349    

DOI:10.3109/00016347909154593

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.The effect of conization upon the course of pregnancy and the fertility has been evaluated. 44 women had a total of 66 pregnancies following conization. These 44 women were compared with an age‐matched group of non‐conized women, as well as with a group of non‐conized women matched for both age and parity.There were more smokers among conized than among non‐conized women. All other descriptive variables were found to be without significant differences between the groups compared.There was no significant difference in the frequency of spontaneous and induced abortion, prematurity or cesarean section between conized and non‐conized women. The second stage of labor was found to be protracted in conized women.Fertility judged by the “latent period” ‐ the time elapsed from the couple started sexual intercourse without use of contraception to the present pregnancy ‐ showed no difference between conized and non‐conized women.We conclude that although a greater number of patients is necessary to permit definite conclusions concerning the risk of pregnancy and delivery complications in conized women, it is of special interest that the present study did not demonstrate an increased risk of spontaneous abortion

ISSN:0001-6349    

DOI:10.3109/00016347909154594

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.An ultrasctructural study of amniotic epithelium and fetal periderm was undertaken in order to investigate the exfoliative capacity in these tissue surfaces in early human pregnancy. Contrary to earlier reports, no exfoliation could be detected from amniotic epithelium, while a heavy detachment of cells and cell fragments was observed from fetal skin. The importance of meticulous tissue preparation is obvious; detachment phenomena are easily produced artifactually by tissue scrapings and improper tissue preparation for morphological investigations.

ISSN:0001-6349    

DOI:10.3109/00016347909154595

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.In cases of missed abortion and missed labor, labor was induced by PGF2α i.a., i.v. and by oxytocin infusion. Platelet function (methods of Born and Breddin), the coagulation system and fibrinolysis have been studied within the three groups.Using PGF2α i.v., the initially increased platelet aggregation showed a tendency to become normal. There was no manifestation of activation of the coagulation system. Fibrinolytic activity showed a slight increase during PGF2α i.v.No essential changes in platelet function, coagulation and fibrinolytic system were found after i.a. injection of PGF2α.When inducing labor by oxytocin i.v., both the coagulation and the fibrinolytic system were slightly activated and platelet aggregation increased.The results and their clinical importance for hemostasis as well as therapeutic consequences are discus

ISSN:0001-6349    

DOI:10.3109/00016347909154596

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.In 64 pregnant women admitted to hospital because of threatened abortion the prognostic value of estradiol‐17‐beta, estriol and human placental lactogen (HPL) in serum was examined. The hormones were determined by radioimmunoassay. Blood samples were taken at regular intervals during admission to hospital and subsequently until delivery. For each hormone a reference range was based on the hormone values obtained from the pregnancies that continued to viability. The study shows that the three hormones examined gave a good indication of the prognosis in threatened abortion, both separately and in combination. The best predictive values were achieved with estradiol and HPL after serial samples. Of these two hormones estradiol is to be preferred because of its fetoplacental ori

ISSN:0001-6349    

DOI:10.3109/00016347909154597

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Sixtytwo patients with spontaneous abortion and 58 with missed abortion were all promptly treated with curettage. The reproductive performance and the subsequent fertility of both groups during a five year period before and after the abotion were compared. To our surprise, no significant differences were found between the two groups.

ISSN:0001-6349    

DOI:10.3109/00016347909154598

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

Abstract.Bromocriptine, 2.5 mg twice a day was tested for its effect on premenstrual tension in a random double‐blind cross‐over trial.1. The compound tended to lessen the symptoms, especially mastodynia.2. Serum prolactin levels around the upper limit of the normal range were significantly lowered. Patients with the highest starting prolactin levels had the most severe symptoms and in these patients the fall in the levels was greatest.3. Serum FSH and LH levels were significantly reciprocally influenced compared with serum prolactin. Serum estradiol‐17‐beta and progesterone did not change during treatment.4. The bromocriptine‐treated cycles were all ovulatory according to basal temperature levels. The luteal phase was prolonged when serum FSH w

ISSN:0001-6349    

DOI:10.3109/00016347909154599

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY